Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Recurrent Grade IV Glioma”

120 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 120 results

Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Early research (Phase 1)Active Not RecruitingNCT07031765
What this trial is testing

Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade Glioma

Who this might be right for
Recurrent High-grade GliomaGrade III AstrocytomaOligodendroglioma+3 more
University of Florida 12
Testing effectiveness (Phase 2)Study completedNCT02858895
What this trial is testing

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Who this might be right for
GlioblastomaGrade IV AstrocytomaGlioblastoma Multiforme+1 more
Medicenna Therapeutics, Inc. 47
Early research (Phase 1)Study completedNCT01491893
What this trial is testing

PVSRIPO for Recurrent Glioblastoma (GBM)

Who this might be right for
GBMGlioblastomaGlioma+1 more
Istari Oncology, Inc. 61
Testing effectiveness (Phase 2)Study completedNCT03027388
What this trial is testing

Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma

Who this might be right for
Astrocytoma, Grades II, III and IVGlioblastoma MultiformeGiant Cell Glioblastoma+2 more
National Cancer Institute (NCI) 7
Early research (Phase 1)Study completedNCT00031083
What this trial is testing

Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas

Who this might be right for
Glioblastoma MultiformeAnaplastic AstrocytomaOligoastrocytoma, Mixed+1 more
Biogen 12
Early research (Phase 1)Study completedNCT00006368
What this trial is testing

Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerGastrointestinal Carcinoid Tumor+5 more
Novartis Pharmaceuticals 60
Early research (Phase 1)Ended earlyNCT00003567
What this trial is testing

Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Who this might be right for
Brain and Central Nervous System TumorsLymphomaUnspecified Adult Solid Tumor, Protocol Specific
Case Comprehensive Cancer Center 8
Early research (Phase 1)Study completedNCT03615404
What this trial is testing

Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma

Who this might be right for
GlioblastomaMalignant GliomaMedulloblastoma Recurrent+3 more
Gary Archer Ph.D. 11
Testing effectiveness (Phase 2)Study completedNCT01290692
What this trial is testing

Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma

Who this might be right for
Grade IV GliomaGrade IV AstrocytomaGlioblastoma Multiforme
TVAX Biomedical 14
Not applicableEnded earlyNCT02967380
What this trial is testing

Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases

Who this might be right for
Adult Anaplastic (Malignant) MeningiomaAdult Anaplastic AstrocytomaAdult Anaplastic Ependymoma+22 more
University of Southern California 14
Early research (Phase 1)Study completedNCT02575794
What this trial is testing

Terameprocol in Treating Patients With Recurrent High Grade Glioma

Who this might be right for
High Grade Glioma (III or IV)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 20
Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Testing effectiveness (Phase 2)Study completedNCT00005952
What this trial is testing

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorHead and Neck Cancer+5 more
Duke University 30
Early research (Phase 1)Active Not RecruitingNCT06410248
What this trial is testing

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent WHO Grade 2 GliomaRecurrent WHO Grade 3 Glioma+1 more
Northwestern University 30
Early research (Phase 1)Study completedNCT00004212
What this trial is testing

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsLymphomaUnspecified Childhood Solid Tumor, Protocol Specific
Daiichi Sankyo
Early research (Phase 1)Study completedNCT00069940
What this trial is testing

Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor

Who this might be right for
Brain and Central Nervous System TumorsGastrointestinal Stromal TumorSarcoma
Dana-Farber Cancer Institute
Early research (Phase 1)Not Yet RecruitingNCT07455045
What this trial is testing

A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)

Who this might be right for
High Grade Glioma (III or IV)Diffuse Midline Glioma (DMG)Glioblastoma (GBM)
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. 40
Testing effectiveness (Phase 2)Study completedNCT03213665
What this trial is testing

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Hodgkin LymphomaAnn Arbor Stage III Non-Hodgkin Lymphoma+38 more
National Cancer Institute (NCI) 20
Early research (Phase 1)Study completedNCT01172964
What this trial is testing

A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas

Who this might be right for
Adult Anaplastic AstrocytomaRecurrent Grade III GliomaRecurrent Grade IV Glioma+9 more
City of Hope Medical Center 15
Load More Results