Testing effectiveness (Phase 2)Ended earlyNCT00393094What this trial is testingBevacizumab and Irinotecan to Treat Brain TumorsWho this might be right forHigh-Grade Gliomas National Cancer Institute (NCI) 31
Early research (Phase 1)Looking for participantsNCT03896568What this trial is testingMSC-DNX-2401 in Treating Patients With Recurrent High-Grade GliomaWho this might be right forIDH1 wt AlleleRecurrent Anaplastic AstrocytomaRecurrent Glioblastoma+2 more M.D. Anderson Cancer Center 36
Early research (Phase 1)Looking for participantsNCT07464925What this trial is testingSafety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade GliomaWho this might be right forGlioblastoma Multiforme of BrainGliomaGlioblastoma Tetragon Biosciences Ltd 30
Early research (Phase 1)Study completedNCT02015819What this trial is testingGenetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade GliomasWho this might be right forAdult Anaplastic AstrocytomaAdult Anaplastic OligodendrogliomaAdult Giant Cell Glioblastoma+4 more City of Hope Medical Center 16
Early research (Phase 1)Ended earlyNCT02255461What this trial is testingPalbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System TumorsWho this might be right forChildhood Choroid Plexus TumorChildhood EpendymoblastomaChildhood Grade III Meningioma+16 more Pediatric Brain Tumor Consortium 35
Early research (Phase 1)Study completedNCT00007813What this trial is testingPeripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid TumorsWho this might be right forBrain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+5 more Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 21
Early research (Phase 1)Ended earlyNCT00572182What this trial is testingMK0752 in Treating Young Patients With Recurrent or Refractory CNS CancerWho this might be right forBrain and Central Nervous System Tumors Pediatric Brain Tumor Consortium 33
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07751744What this trial is testingPhase 1/2 Study Evaluating the Safety, PK/PD, and Clinical Activity of Oral JBI-778 in Patients With Brain Metastases, Leptomeningeal Disease, or Recurrent High Grade GliomaWho this might be right forBrain Metastases From Solid TumorsLeptomeningeal DiseaseHigh Grade Glioma (HGG)+1 more Jubilant Therapeutics Inc. 113
Testing effectiveness (Phase 2)Study completedNCT00404248What this trial is testingTetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade GliomaWho this might be right forBrain and Central Nervous System Tumors Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 35
Testing effectiveness (Phase 2)Ended earlyNCT01478321What this trial is testingEfficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent GliomasWho this might be right forAdult Anaplastic AstrocytomaAdult Anaplastic EpendymomaAdult Anaplastic Oligodendroglioma+2 more Northwestern University 54
Early research (Phase 1)Study completedNCT02186509What this trial is testingAlisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade GliomasWho this might be right forAdult Anaplastic AstrocytomaAdult Anaplastic EpendymomaAdult Anaplastic Oligodendroglioma+11 more Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 17
Very early researchLooking for participantsNCT07017816What this trial is testingCDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.Who this might be right forCNS MalignanciesMedulloblastoma RecurrentATRT Recurrent+4 more Children's National Research Institute 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT04201457What this trial is testingA Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF AberrationWho this might be right forLow Grade Glioma (LGG) of Brain With BRAF AberrationHigh Grade Glioma (HGG) of the Brain With BRAF AberrationLow Grade Glioma of Brain With Neurofibromatosis Type 1 Pediatric Brain Tumor Consortium 57
Testing effectiveness (Phase 2)Study completedNCT01462695What this trial is testingSunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or EpendymomaWho this might be right forChildhood Cerebellar Anaplastic AstrocytomaChildhood Cerebral Anaplastic AstrocytomaChildhood Cerebral Astrocytoma+8 more National Cancer Institute (NCI) 30
Early research (Phase 1)Looking for participantsNCT06773481What this trial is testingBC008-1A Injection for Recurrent CNS WHO G4 GliomaWho this might be right forGliomaGlioma Tumor RecurrenceGlioma, Recurrent High Grade+2 more Sichuan Luzhou Buchang Biopharmaceutical Co., Ltd. 40
Testing effectiveness (Phase 2)Study completedNCT02263105What this trial is testingEfficacy and Tolerability of Cisplatin Plus Alternating Weekly Temozolomide in Recurrent High-grade GliomasWho this might be right forHigh-grade Gliomas Huashan Hospital 67
Early research (Phase 1)Ended earlyNCT00623077What this trial is testingMT2004-30: Tomotherapy for Solid TumorsWho this might be right forBrain and Central Nervous System TumorsKidney CancerLiver Cancer+2 more Masonic Cancer Center, University of Minnesota 23
Testing effectiveness (Phase 2)Study completedNCT02971319What this trial is testingTechnical Performance Assessment of Tc-99m Tetrofosmin for Differentiation of Recurrence vs Radiation Necrosis in Patients With GliomaWho this might be right forGlioma (Diagnosis) Proactina S.A. 32
Very early researchStudy completedNCT03834740What this trial is testingA Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for ResectionWho this might be right forGlioblastoma MultiformeGlioma of Brain St. Joseph's Hospital and Medical Center, Phoenix 27
Early research (Phase 1)Not Yet RecruitingNCT07826949What this trial is testingSRN-101 Administered Prior to Surgical Resection in Adults With Recurrent High-Grade Glioma.Who this might be right forRecurrent High-Grade GliomasBrain NeoplasmGlioma Nicholas Butowski 6