Early research (Phase 1)Study completedNCT03154996What this trial is testingChronic Convection Enhanced Delivery of TopotecanWho this might be right forGliomas Columbia University 5
Early research (Phase 1)Study completedNCT00063973What this trial is testingCilengitide in Treating Children With Refractory Primary Brain TumorsWho this might be right forChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+23 more National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07567469What this trial is testingA Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressive High-Grade Glioma or Posterior Fossa-A EpendymomaWho this might be right forHigh-Grade Glioma (HGG)Posterior Fossa-A Ependymoma Regeneron Pharmaceuticals 120
Testing effectiveness (Phase 2)Study completedNCT00107003What this trial is testingGW572016 to Treat Recurrent Malignant Brain TumorsWho this might be right forGliomaBrain TumorGlioblastoma Multiforme+3 more National Cancer Institute (NCI) 9
Early research (Phase 1)UnknownNCT06585527What this trial is testingClinical Study on the Safety and Efficacy of TS-2021 in the Treatment of Recurrent Malignant GliomaWho this might be right forGlioblastoma MultiformeGlioma, Malignant Beijing Neurosurgical Institute 30
Testing effectiveness (Phase 2)Looking for participantsNCT07410494What this trial is testingBiomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid TumorsWho this might be right forCancerBreast CancerNon-Small Cell Lung Cancer (NSCLC)+10 more Essen Biotech 85
Early research (Phase 1)Study completedNCT00005796What this trial is testingCombination Chemotherapy Plus Gene Therapy in Treating Patients With CNS TumorsWho this might be right forBone Marrow SuppressionBrain and Central Nervous System TumorsDrug/Agent Toxicity by Tissue/Organ Indiana University 10
Testing effectiveness (Phase 2)Ended earlyNCT03973918What this trial is testingStudy of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGGWho this might be right forHigh Grade GliomaBRAF V600EBRAF V600K+4 more Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 5
Testing effectiveness (Phase 2)Study completedNCT00012038What this trial is testingChemotherapy in Treating Patients With Progressive or Recurrent Brain TumorsWho this might be right forBrain and Central Nervous System Tumors New Approaches to Brain Tumor Therapy Consortium
Early research (Phase 1)Active Not RecruitingNCT05561374What this trial is testingStudy of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade GliomaWho this might be right forHigh-grade GliomaOligodendrogliomaAstrocytoma+1 more Oblato, Inc. 16
Large-scale testing (Phase 3)WithdrawnNCT01961934What this trial is testingC11-Sodium Acetate PET/CT Imaging Evaluation in Brain Glioma, Post Therapy Necrosis and Pseudo-progressionWho this might be right forGliomas Phoenix Molecular Imaging
Very early researchUnknownNCT04045847What this trial is testingCD147-CART Cells in Patients With Recurrent Malignant Glioma.Who this might be right forRecurrent GlioblastomaCD147 Positive Xijing Hospital 31
Testing effectiveness (Phase 2)Study completedNCT03213678What this trial is testingSamotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)Who this might be right forAdvanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+30 more National Cancer Institute (NCI) 18
Early research (Phase 1)Looking for participantsNCT07664176What this trial is testingNgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain TumorsWho this might be right forDiffuse Midline Glioma or Diffuse Intrinsic Pontine GliomaHigh Grade GliomasMedulloblastoma Recurrent+3 more Children's National Research Institute 30
Early research (Phase 1)Study completedNCT00022360What this trial is testingTaurolidine in Treating Patients With Recurrent or Progressive GliomaWho this might be right forBrain and Central Nervous System Tumors Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT04730349What this trial is testingBempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant CancerWho this might be right forEpendymomaEwing SarcomaHigh-grade Glioma+7 more Bristol-Myers Squibb 15
Testing effectiveness (Phase 2)Study completedNCT01403610What this trial is testingSafety and Efficacy Study of TH-302 CNS Penetration in Recurrent High Grade Astrocytoma Following BevacizumabWho this might be right forHIGH GRADE GLIOMA The University of Texas Health Science Center at San Antonio 28
Testing effectiveness (Phase 2)Study completedNCT00014573What this trial is testingChemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain CancerWho this might be right forBrain and Central Nervous System Tumors Barbara Ann Karmanos Cancer Institute
Early research (Phase 1)Study completedNCT01250470What this trial is testingVaccine Therapy and Sargramostim in Treating Patients With Malignant GliomaWho this might be right forAnaplastic AstrocytomaAnaplastic OligoastrocytomaAnaplastic Oligodendroglioma+5 more Roswell Park Cancer Institute 9
Early research (Phase 1)Ended earlyNCT00238173What this trial is testingAcetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain TumorsWho this might be right forBone Marrow SuppressionBrain and Central Nervous System TumorsDrug/Agent Toxicity by Tissue/Organ+1 more OHSU Knight Cancer Institute 2