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Results for “Recurrent IDH”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT05345002
What this trial is testing

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Who this might be right for
GliomaIDH MutationAstrocytoma+1 more
Stephen Bagley, MD, MSCE 55
Testing effectiveness (Phase 2)Looking for participantsNCT05588141
What this trial is testing

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Who this might be right for
Brain TumorCancer
National Cancer Institute (NCI) 96
Not applicableLooking for participantsNCT06283927
What this trial is testing

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

Who this might be right for
GlioblastomaGlioblastoma MultiformeGlioblastoma, IDH-wildtype+5 more
Jasper Gerritsen 464
Early research (Phase 1)Looking for participantsNCT07755397
What this trial is testing

First in Human Multicenter Open Name Dose-increase, Consolidation Method to Study Safety Drug-level in Blood & Drug Metabolism Clinical Activity of Oral JBI-778 in Lung Cancer Patients With, Without Brain Metastasis IDH Mutated WHO Grade 3,4 Recurrent Glioma, Salivary Glands Tumor

Who this might be right for
NSCLC Patients With EGFR Activating MutationAdenoid Cystic Carcinoma MetastaticAdenoid Cystic Carcinoma of the Head and Neck
Jubilant Therapeutics India Limited 30
Large-scale testing (Phase 3)Not Yet RecruitingNCT07349693
What this trial is testing

Comparison of Cerebraca Wafer Plus Temozolomide Versus Temozolomide Alone in Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-Wildtype
Everfront Biotech Co., Ltd. 175
Very early researchLooking for participantsNCT06552260
What this trial is testing

A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma

Who this might be right for
GlioblastomaRecurrent GlioblastomaBrain Tumor
Ugonma Chukwueke 27
Early research (Phase 1)Looking for participantsNCT07089641
What this trial is testing

ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial

Who this might be right for
GlioblastomaGlioblastoma, IDH-WildtypeGliosarcoma+3 more
Jonsson Comprehensive Cancer Center 50
Testing effectiveness (Phase 2)Looking for participantsNCT05465954
What this trial is testing

Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma

Who this might be right for
High Grade Astrocytic TumorRecurrent Glioblastoma, IDH-WildtypeRecurrent Gliosarcoma
Mayo Clinic 54
Testing effectiveness (Phase 2)WithdrawnNCT06328036
What this trial is testing

Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-Wildtype
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Early research (Phase 1)Looking for participantsNCT07733674
What this trial is testing

Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC)

Who this might be right for
Glioblastoma Multiforme (GBM)Pancreatic Ductal Adenocarcinoma (PDAC)
Radiomedix, Inc. 20
Testing effectiveness (Phase 2)Looking for participantsNCT07831369
What this trial is testing

VISTA: Valproic Acid, Irinotecan, and Simvastatin for Recurrent Glioma

Who this might be right for
GlioblastomaAstrocytoma, IDH-Mutant, Grade 4
Inova Health Care Services 52
Testing effectiveness (Phase 2)Looking for participantsNCT07301268
What this trial is testing

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Who this might be right for
Glioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT04145115
What this trial is testing

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 4Diffuse GliomaGlioblastoma, IDH-Wildtype+1 more
National Cancer Institute (NCI) 37
Very early researchEnrolling By InvitationNCT07520214
What this trial is testing

Clinical Study on the Safety and Immunogenicity of Specific Cancer Vaccines in Preventing Recurrence of Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeGlioblastom WHO Grade 4
Beijing Neurosurgical Institute 9
Large-scale testing (Phase 3)Looking for participantsNCT03970447
What this trial is testing

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Who this might be right for
Glioblastoma
Global Coalition for Adaptive Research 2,250
Early research (Phase 1)Looking for participantsNCT06860594
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 2Recurrent Adult Diffuse Hemispheric Glioma, H3 G34-MutantRecurrent Adult Diffuse Midline Glioma, H3 K27-Mutant+4 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Looking for participantsNCT06455605
What this trial is testing

D2C7-IT + 2141-V11 Combination Post-resection in rGBM

Who this might be right for
Recurrent Glioblastoma IDH Wildtype
Darell Bigner 46
Early research (Phase 1)Study completedNCT05441514
What this trial is testing

Enasidenib in Combination With Cobimetinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia
City of Hope Medical Center 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT04910022
What this trial is testing

Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent Glioblastoma

Who this might be right for
GlioblastomaDiffuse Glioma
Nerviano Medical Sciences 150
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