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Results for “Recurrent Low-grade Gliomas”

93 trials

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Showing 20 of 93 results

Large-scale testing (Phase 3)Active Not RecruitingNCT04576117
What this trial is testing

Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Who this might be right for
Recurrent Low Grade AstrocytomaRecurrent WHO Grade 2 GliomaRefractory Low Grade Astrocytoma+2 more
National Cancer Institute (NCI) 300
Testing effectiveness (Phase 2)Study completedNCT00381797
What this trial is testing

Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma

Who this might be right for
Childhood Cerebral Anaplastic AstrocytomaChildhood OligodendrogliomaChildhood Spinal Cord Neoplasm+3 more
National Cancer Institute (NCI) 97
Testing effectiveness (Phase 2)Looking for participantsNCT07110246
What this trial is testing

Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

Who this might be right for
BRAF V600 MutationLow-grade GliomaLow Grade Glioma of Brain+1 more
University of California, San Francisco 96
Testing effectiveness (Phase 2)UnknownNCT00360945
What this trial is testing

Cisplatin and Temozolomide in Treating Young Patients With Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Children's Cancer and Leukaemia Group 87
Early research (Phase 1)Study completedNCT00272350
What this trial is testing

ZD6474 to Treat Advanced Brain Cancer in Patients

Who this might be right for
Recurrent High-Grade GliomasProgressive Low-Grade GliomasMalignant Gliomas
National Cancer Institute (NCI) 83
Testing effectiveness (Phase 2)Study completedNCT00003466
What this trial is testing

Temozolomide in Treating Patients With Progressive Low-Grade Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Duke University 100
Not applicableStudy completedNCT00006342
What this trial is testing

Genetic Study in Patients Receiving Treatment for Hodgkin's Disease or Childhood Brain Tumor

Who this might be right for
Brain and Central Nervous System TumorsLymphoma
Duke University 19
Early research (Phase 1)Study completedNCT00063973
What this trial is testing

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+23 more
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Looking for participantsNCT04923126
What this trial is testing

SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma

Who this might be right for
Low-Grade GliomaRecurrent Low-Grade GliomaProgressive Low-Grade Glioma
St. Jude Children's Research Hospital 132
Large-scale testing (Phase 3)Active Not RecruitingNCT00978458
What this trial is testing

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Who this might be right for
Brain and Central Nervous System TumorsNeurotoxicity
Eastern Cooperative Oncology Group 540
Early research (Phase 1)Looking for participantsNCT07664176
What this trial is testing

NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors

Who this might be right for
Diffuse Midline Glioma or Diffuse Intrinsic Pontine GliomaHigh Grade GliomasMedulloblastoma Recurrent+3 more
Children's National Research Institute 30
Early research (Phase 1)Ended earlyNCT00238173
What this trial is testing

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

Who this might be right for
Bone Marrow SuppressionBrain and Central Nervous System TumorsDrug/Agent Toxicity by Tissue/Organ+1 more
OHSU Knight Cancer Institute 2
Testing effectiveness (Phase 2)Study completedNCT01466686
What this trial is testing

Low Dose Radiation Therapy for Glioblastoma Multiforme

Who this might be right for
High Grade Glioma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 31
Not applicableStudy completedNCT00002485
What this trial is testing

Development of Strategies to Increase Enrollment in Clinical Trials for Children With Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
Children's Oncology Group 359
Testing effectiveness (Phase 2)Study completedNCT01081223
What this trial is testing

Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma

Who this might be right for
GliomaHigh Grade AstrocytomaGlioblastoma Multiforme
TVAX Biomedical 12
Early research (Phase 1)Looking for participantsNCT04485559
What this trial is testing

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

Who this might be right for
Recurrent World Health Organization (WHO) Grade II GliomaLow-grade GliomaHigh-Grade Glioma (HGG)
University of California, San Francisco 50
Early research (Phase 1)Study completedNCT00946335
What this trial is testing

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+25 more
National Cancer Institute (NCI) 31
Early research (Phase 1)Study completedNCT00052780
What this trial is testing

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+22 more
National Cancer Institute (NCI) 72
Testing effectiveness (Phase 2)WithdrawnNCT05222165
What this trial is testing

Study With Infigratinib in Subjects With Advanced Solid and CNS Tumors or Recurrent or Progressive Low-Grade Glioma With Selected FGFR1-3 Alterations

Who this might be right for
Advanced Solid TumorCNS TumorRecurrent WHO Grade II Glioma
Helsinn Healthcare SA
Early research (Phase 1)Study completedNCT00053963
What this trial is testing

FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia

Who this might be right for
Blastic Phase Chronic Myelogenous LeukemiaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
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