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Results for “Recurrent Metastatic Malignant Neoplasm in the Leptomeninges”

25 trials

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Showing 20 of 25 results

Early research (Phase 1)Looking for participantsNCT05184816
What this trial is testing

Deferoxamine (DFO) in People With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center 35
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Early research (Phase 1)Active Not RecruitingNCT04661384
What this trial is testing

Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma

Who this might be right for
EpendymomaGlioblastomaMedulloblastoma+1 more
City of Hope Medical Center 10
Testing effectiveness (Phase 2)Study completedNCT00992602
What this trial is testing

Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer

Who this might be right for
Central Nervous System MetastasesLeptomeningeal MetastasesRecurrent Breast Cancer+2 more
University of Washington 3
Early research (Phase 1)Study completedNCT02423525
What this trial is testing

Safety Study of Afatinib for Brain Cancer

Who this might be right for
Brain Cancer
Santosh Kesari 24
Early research (Phase 1)Study completedNCT00002750
What this trial is testing

Melphalan in Patients With Neoplastic Meningitis

Who this might be right for
Brain and Central Nervous System TumorsExtragonadal Germ Cell TumorLeukemia+2 more
Duke University 6
Testing effectiveness (Phase 2)Study completedNCT00450866
What this trial is testing

Epothilone B in Treating Patients With CNS Metastases From Breast Cancer

Who this might be right for
Breast CancerMetastatic Cancer
David Peereboom, MD 55
Very early researchStudy completedNCT00424242
What this trial is testing

Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Northwestern University 15
Early research (Phase 1)Ended earlyNCT00512460
What this trial is testing

RTA 744 Injection in Patients With Leptomeningeal Disease

Who this might be right for
Neoplastic MeningitisSolid TumorLymphoma+2 more
M.D. Anderson Cancer Center 7
Early research (Phase 1)Study completedNCT00416923
What this trial is testing

Intrathecal Rituximab in Treating Patients With Recurrent CNS Lymphoma

Who this might be right for
Brain and Central Nervous System TumorsLymphoma
University of California, San Francisco 10
Early research (Phase 1)Ended earlyNCT00089245
What this trial is testing

Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer

Who this might be right for
Brain and Central Nervous System TumorsNeuroblastomaSarcoma
Y-mAbs Therapeutics 177
Testing effectiveness (Phase 2)Looking for participantsNCT06058988
What this trial is testing

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

Who this might be right for
Brain CancerGlioblastomaMetastatic Cancer+2 more
Memorial Sloan Kettering Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT07264569
What this trial is testing

Evaluate the Safety, Tolerability, Biodistribution Characteristics and Preliminary Efficacy of BioTTT001

Who this might be right for
Meningeal Metastasis
Henan Cancer Hospital 42
Early research (Phase 1)Ended earlyNCT00527410
What this trial is testing

A Safety Study of RTA 744 in Recurrent, Progressive or Refractory Neoplastic Meningitis

Who this might be right for
Leptomeningeal Carcinomatosis
Biogen 9
Early research (Phase 1)UnknownNCT00003073
What this trial is testing

Chemotherapy in Treating Young Patients With Recurrent or Refractory Meningeal Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Pacira Pharmaceuticals, Inc 15
Testing effectiveness (Phase 2)Ended earlyNCT02684071
What this trial is testing

Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors

Who this might be right for
Recurrent Childhood MedulloblastomaRecurrent Childhood EpendymomaChildhood Atypical Teratoid/Rhabdoid Tumor+2 more
Nicklaus Children's Hospital f/k/a Miami Children's Hospital 3
Early research (Phase 1)Study completedNCT00005842
What this trial is testing

Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer

Who this might be right for
Cancer
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Study completedNCT00005811
What this trial is testing

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

Who this might be right for
AIDS-related Diffuse Large Cell LymphomaAIDS-related Diffuse Mixed Cell LymphomaAIDS-related Diffuse Small Cleaved Cell Lymphoma+17 more
National Cancer Institute (NCI) 77
Early research (Phase 1)Study completedNCT00003462
What this trial is testing

Intrathecal Busulfan in Treating Patients With Recurrent, Refractory, or Metastatic Leptomeningeal Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Duke University 20
Not applicableUnknownNCT04778800
What this trial is testing

A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY)

Who this might be right for
NSCLCBrain MetastasesLeptomeningeal Metastasis
Henan Cancer Hospital 60
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