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Results for “Recurrent Mixed Phenotype Acute Leukemia”

40 trials

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Showing 20 of 40 results

Early research (Phase 1)Active Not RecruitingNCT04872790
What this trial is testing

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Mixed Phenotype Acute Leukemia+2 more
OHSU Knight Cancer Institute 20
Early research (Phase 1)Active Not RecruitingNCT06325748
What this trial is testing

SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS

Who this might be right for
AML/MDSCD33 Expressing Hematological MalignanciesFLT3 Expressing Hematological Malignancies
Senti Biosciences 21
Early research (Phase 1)Ended earlyNCT04526795
What this trial is testing

Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia

Who this might be right for
Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveRecurrent Acute Biphenotypic LeukemiaRecurrent Acute Lymphoblastic Leukemia+8 more
M.D. Anderson Cancer Center 19
Testing effectiveness (Phase 2)Looking for participantsNCT04047641
What this trial is testing

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts 20 Percent or More of Bone Marrow Nucleated CellsHigh Risk Myelodysplastic Syndrome+5 more
M.D. Anderson Cancer Center 80
Early research (Phase 1)Ended earlyNCT01887587
What this trial is testing

Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia

Who this might be right for
Relapsed or Refractory Acute Lymphoblastic LeukemiaRelapsed or Refractory Lymphoblastic LymphomaMixed Phenotype Acute Leukemia
Ehab L Atallah 5
Testing effectiveness (Phase 2)Study completedNCT02921061
What this trial is testing

Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS

Who this might be right for
Mixed Phenotype Acute LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Myeloid Leukemia+4 more
Fred Hutchinson Cancer Center 28
Testing effectiveness (Phase 2)WithdrawnNCT02718755
What this trial is testing

Phase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic Malignancies

Who this might be right for
Hematologic Malignancy
M.D. Anderson Cancer Center
Early research (Phase 1)Active Not RecruitingNCT02879695
What this trial is testing

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent Mixed Phenotype Acute LeukemiaRefractory B Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 28
Testing effectiveness (Phase 2)Ended earlyNCT01028716
What this trial is testing

Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Acute Biphenotypic LeukemiaAcute Erythroid Leukemia in RemissionAcute Leukemia in Remission+27 more
Fred Hutchinson Cancer Center 46
Testing effectiveness (Phase 2)WithdrawnNCT05320380
What this trial is testing

The Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent B Acute Lymphoblastic LeukemiaRecurrent Mixed Phenotype Acute Leukemia+5 more
Children's Oncology Group
Testing effectiveness (Phase 2)Active Not RecruitingNCT05761171
What this trial is testing

Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Who this might be right for
Recurrent Acute Leukemia of Ambiguous LineageRecurrent Acute Lymphoblastic LeukemiaRecurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage+9 more
Children's Oncology Group 78
Testing effectiveness (Phase 2)Looking for participantsNCT06928662
What this trial is testing

Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse

Who this might be right for
Acute Myeloid LeukemiaAcute Undifferentiated LeukemiaMixed Phenotype Acute Leukemia+11 more
Fred Hutchinson Cancer Center 36
Testing effectiveness (Phase 2)Study completedNCT03096782
What this trial is testing

Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia+19 more
M.D. Anderson Cancer Center 6
Testing effectiveness (Phase 2)Looking for participantsNCT03683433
What this trial is testing

Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation

Who this might be right for
Acute Bilineal LeukemiaAcute Biphenotypic LeukemiaChronic Myelomonocytic Leukemia+4 more
M.D. Anderson Cancer Center 50
Testing effectiveness (Phase 2)Ended earlyNCT02399917
What this trial is testing

Lirilumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Acute Biphenotypic LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+1 more
M.D. Anderson Cancer Center 36
Testing effectiveness (Phase 2)Looking for participantsNCT04797767
What this trial is testing

Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

Who this might be right for
Acute Biphenotypic LeukemiaAcute Myeloid LeukemiaMixed Phenotype Acute Leukemia+10 more
University of Washington 62
Testing effectiveness (Phase 2)Study completedNCT02220985
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+20 more
Fred Hutchinson Cancer Center 84
Testing effectiveness (Phase 2)Study completedNCT00723099
What this trial is testing

Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAggressive Non-Hodgkin Lymphoma+23 more
Fred Hutchinson Cancer Center 73
Early research (Phase 1)Looking for participantsNCT03326921
What this trial is testing

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Who this might be right for
Juvenile Myelomonocytic LeukemiaRecurrent Acute Biphenotypic LeukemiaRecurrent Acute Undifferentiated Leukemia+26 more
Fred Hutchinson Cancer Center 24
Testing effectiveness (Phase 2)Study completedNCT02135874
What this trial is testing

Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

Who this might be right for
Acute Bilineal LeukemiaAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+5 more
M.D. Anderson Cancer Center 16
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