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Results for “Recurrent Pediatric High Grade Glioma”

107 trials

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Showing 20 of 107 results

Testing effectiveness (Phase 2)Study completedNCT00002608
What this trial is testing

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

Who this might be right for
Adrenocortical CarcinomaBrain and Central Nervous System TumorsHead and Neck Cancer+4 more
Ottawa Regional Cancer Centre 30
Testing effectiveness (Phase 2)Study completedNCT00070525
What this trial is testing

Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma

Who this might be right for
Childhood High-grade Cerebral AstrocytomaChildhood OligodendrogliomaRecurrent Childhood Brain Stem Glioma+5 more
National Cancer Institute (NCI) 90
Testing effectiveness (Phase 2)WithdrawnNCT00053040
What this trial is testing

Immunotoxin Therapy in Treating Children With Recurrent Malignant Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium
Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Testing effectiveness (Phase 2)Study completedNCT03526250
What this trial is testing

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more
National Cancer Institute (NCI) 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT03210714
What this trial is testing

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Childhood Malignant Germ Cell Tumor+29 more
National Cancer Institute (NCI) 20
Very early researchStudy completedNCT03250520
What this trial is testing

Application of Palliative Treatment in Children With Brain Stem Glioma and Recurrent High-grade Tumors in the Central Nervous System With the Nanomaterial NPt-Ca

Who this might be right for
Brain Tumor, Pediatric, Brainstem GliomaBrain Tumor, Pediatric, Recurrent
Hospital Infantil de Mexico Federico Gomez 8
Early research (Phase 1)Looking for participantsNCT07492316
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB)

Who this might be right for
Recurrent Medulloblastoma
University of Florida 24
Early research (Phase 1)Active Not RecruitingNCT03299309
What this trial is testing

PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma

Who this might be right for
Recurrent MedulloblastomaRecurrent Brain Tumor, ChildhoodMalignant Glioma
Daniel Landi 30
Testing effectiveness (Phase 2)Study completedNCT03245151
What this trial is testing

Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors

Who this might be right for
Recurrent and Refractory Solid Tumors
Eisai Inc. 64
Early research (Phase 1)Not Yet RecruitingNCT06946680
What this trial is testing

IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)

Who this might be right for
High-grade GliomaDiffuse Intrinsic Pontine Glioma
University of Florida 24
Testing effectiveness (Phase 2)Study completedNCT02343406
What this trial is testing

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas

Who this might be right for
Glioblastoma
AbbVie 266
Testing effectiveness (Phase 2)Active Not RecruitingNCT03155620
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+42 more
National Cancer Institute (NCI) 1,377
Early research (Phase 1)Ended earlyNCT05429502
What this trial is testing

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Who this might be right for
Neuroblastoma
Novartis Pharmaceuticals 12
Early research (Phase 1)Study completedNCT00303940
What this trial is testing

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorKidney Cancer+5 more
National Institutes of Health Clinical Center (CC) 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)Ended earlyNCT03690869
What this trial is testing

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Who this might be right for
Relapsed Solid TumorRefractory Solid TumorRelapsed Central Nervous System Tumor+3 more
Regeneron Pharmaceuticals 57
Early research (Phase 1)Study completedNCT00107458
What this trial is testing

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

Who this might be right for
Brain and Central Nervous System TumorsUnspecified Childhood Solid Tumor, Protocol Specific
Children's Oncology Group 26
Early research (Phase 1)WithdrawnNCT05082493
What this trial is testing

A Multicenter, Study of the Safety and Pharmacokinetics of Intravenously Infused Berubicin in Pediatric Patients With Progressive, Refractory, or Recurrent High Grade Gliomas

Who this might be right for
High Grade Glioma
WPD Pharmaceuticals Sp. z o.o.
Early research (Phase 1)Study completedNCT00063973
What this trial is testing

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+23 more
National Cancer Institute (NCI) 24
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