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Results for “Recurrent WHO Grade 3 Glioma”

38 trials

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Showing 20 of 38 results

Large-scale testing (Phase 3)Active Not RecruitingNCT04576117
What this trial is testing

Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Who this might be right for
Recurrent Low Grade AstrocytomaRecurrent WHO Grade 2 GliomaRefractory Low Grade Astrocytoma+2 more
National Cancer Institute (NCI) 300
Early research (Phase 1)Active Not RecruitingNCT06410248
What this trial is testing

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent WHO Grade 2 GliomaRecurrent WHO Grade 3 Glioma+1 more
Northwestern University 30
Not applicableNo Longer AvailableNCT02755987
What this trial is testing

Expanded Access to ANG1005 for Individual Patients

Who this might be right for
Anaplastic AstrocytomaAnaplastic OligodendrogliomaBreast Cancer With Recurrent Brain Metastases+1 more
Angiochem Inc
Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Early research (Phase 1)Active Not RecruitingNCT03389230
What this trial is testing

Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma

Who this might be right for
GlioblastomaMalignant GliomaRecurrent Glioma+2 more
City of Hope Medical Center 29
Testing effectiveness (Phase 2)Looking for participantsNCT06444412
What this trial is testing

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

Who this might be right for
WHO Grade 3 GliomaWHO Grade 4 Glioma
Mayo Clinic 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT03212274
What this trial is testing

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

Who this might be right for
Advanced Malignant Solid NeoplasmGlioblastomaRecurrent Cholangiocarcinoma+4 more
National Cancer Institute (NCI) 89
Testing effectiveness (Phase 2)Study completedNCT00492089
What this trial is testing

Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic EpendymomaAdult Anaplastic Meningioma+84 more
National Cancer Institute (NCI) 11
Early research (Phase 1)Ended earlyNCT01989052
What this trial is testing

Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma

Who this might be right for
Malignant Glioma (WHO Grade III or IV)
Annick Desjardins 9
Early research (Phase 1)Active Not RecruitingNCT02192359
What this trial is testing

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

Who this might be right for
Recurrent Anaplastic AstrocytomaRecurrent Anaplastic OligoastrocytomaRecurrent Anaplastic Oligodendroglioma+4 more
City of Hope Medical Center 18
Very early researchEnded earlyNCT03927274
What this trial is testing

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

Who this might be right for
Glioma of Brain
H. Lee Moffitt Cancer Center and Research Institute 3
Very early researchEnded earlyNCT02500459
What this trial is testing

Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection

Who this might be right for
Brain TumorHigh Grade Glioma
Michael Vogelbaum, MD, PhD 9
Very early researchWithdrawnNCT03193463
What this trial is testing

Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy

Who this might be right for
Glioma
Michael Vogelbaum, MD, PhD
Testing effectiveness (Phase 2)Looking for participantsNCT05765812
What this trial is testing

Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeAstrocytoma, Grade III
Debiopharm International SA 116
Testing effectiveness (Phase 2)Study completedNCT02343406
What this trial is testing

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas

Who this might be right for
Glioblastoma
AbbVie 266
Early research (Phase 1)Looking for participantsNCT04540107
What this trial is testing

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

Who this might be right for
Recurrent World Health Organization (WHO) Grade II GliomaRecurrent WHO Grade III GliomaWHO Grade II Glioma+1 more
Susan Chang 300
Testing effectiveness (Phase 2)Study completedNCT03914742
What this trial is testing

BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations

Who this might be right for
IDH1 MutationIDH2 MutationRecurrent Glioblastoma+2 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 67
Testing effectiveness (Phase 2)Study completedNCT04044937
What this trial is testing

Fluoroethyltyrosine for Evaluation of Intracranial Neoplasms

Who this might be right for
Intracranial NeoplasmLow Grade GliomaRecurrent Glioblastoma+2 more
Thomas Hope 143
Early research (Phase 1)Active Not RecruitingNCT04214392
What this trial is testing

Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma

Who this might be right for
Recurrent GlioblastomaRecurrent Malignant GliomaRecurrent WHO Grade II Glioma+1 more
City of Hope Medical Center 19
Early research (Phase 1)Active Not RecruitingNCT03749187
What this trial is testing

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

Who this might be right for
GlioblastomaIDH1 Gene MutationIDH2 Gene Mutation+7 more
University of California, San Francisco 78
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