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Results for “Recurrent WHO Grade 3 Glioma”

38 trials

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Showing 20 of 38 results

Very early researchEnded earlyNCT03927274
What this trial is testing

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

Who this might be right for
Glioma of Brain
H. Lee Moffitt Cancer Center and Research Institute 3
Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Early research (Phase 1)Looking for participantsNCT04573140
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

Who this might be right for
Adult GlioblastomaHigh Grade GliomaWHO Grade III or IV Malignant Glioma
University of Florida 28
Testing effectiveness (Phase 2)Looking for participantsNCT06444412
What this trial is testing

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

Who this might be right for
WHO Grade 3 GliomaWHO Grade 4 Glioma
Mayo Clinic 25
Not applicableStudy completedNCT00255671
What this trial is testing

Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders

Who this might be right for
Brain and Central Nervous System TumorsMetastatic CancerRadiation Toxicity
Case Comprehensive Cancer Center 76
Early research (Phase 1)Ended earlyNCT01989052
What this trial is testing

Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma

Who this might be right for
Malignant Glioma (WHO Grade III or IV)
Annick Desjardins 9
Not applicableLooking for participantsNCT06975332
What this trial is testing

Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) Progression

Who this might be right for
GlioblastomaHigh-Grade GliomasGrade III Astrocytoma+1 more
Medical University of Warsaw 35
Very early researchStudy completedNCT02278510
What this trial is testing

Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma

Who this might be right for
Malignant GliomaWHO Grade III or IV Recurrent Glioma
Michael Vogelbaum, MD, PhD 3
Testing effectiveness (Phase 2)Looking for participantsNCT05765812
What this trial is testing

Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeAstrocytoma, Grade III
Debiopharm International SA 116
Not applicableStudy completedNCT03450850
What this trial is testing

Study Of NOVOTTF-200A In Bevacizumab-Naive Subjects With Recurrent Grade III Malignant Astrocytoma

Who this might be right for
Astrocytoma, Grade III
Daniela A. Bota 1
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Testing effectiveness (Phase 2)Study completedNCT00492089
What this trial is testing

Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic EpendymomaAdult Anaplastic Meningioma+84 more
National Cancer Institute (NCI) 11
Testing effectiveness (Phase 2)Study completedNCT03914742
What this trial is testing

BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations

Who this might be right for
IDH1 MutationIDH2 MutationRecurrent Glioblastoma+2 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 67
Early research (Phase 1)Ended earlyNCT04047303
What this trial is testing

CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma

Who this might be right for
AstrocytomaGlioblastoma
Celgene 20
Early research (Phase 1)Looking for participantsNCT04540107
What this trial is testing

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

Who this might be right for
Recurrent World Health Organization (WHO) Grade II GliomaRecurrent WHO Grade III GliomaWHO Grade II Glioma+1 more
Susan Chang 300
Early research (Phase 1)Active Not RecruitingNCT03749187
What this trial is testing

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

Who this might be right for
GlioblastomaIDH1 Gene MutationIDH2 Gene Mutation+7 more
University of California, San Francisco 78
Testing effectiveness (Phase 2)Active Not RecruitingNCT03212274
What this trial is testing

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

Who this might be right for
Advanced Malignant Solid NeoplasmGlioblastomaRecurrent Cholangiocarcinoma+4 more
National Cancer Institute (NCI) 89
Early research (Phase 1)Looking for participantsNCT04732065
What this trial is testing

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

Who this might be right for
Diffuse Midline Glioma (DMG)GlioblastomaRecurrent Ependymoma+5 more
Sabine Mueller, MD, PhD 208
Testing effectiveness (Phase 2)Study completedNCT01817751
What this trial is testing

Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma

Who this might be right for
GlioblastomaRecurrent Adult Brain NeoplasmMalignant Glioma+1 more
Virginia Commonwealth University 47
Early research (Phase 1)Looking for participantsNCT06410248
What this trial is testing

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent WHO Grade 2 GliomaRecurrent WHO Grade 3 Glioma+1 more
Northwestern University 30
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