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Results for “Recurrent WHO Grade 3 Glioma”

38 trials

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Showing 20 of 38 results

Not applicableLooking for participantsNCT06975332
What this trial is testing

Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) Progression

Who this might be right for
GlioblastomaHigh-Grade GliomasGrade III Astrocytoma+1 more
Medical University of Warsaw 35
Early research (Phase 1)Active Not RecruitingNCT02192359
What this trial is testing

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

Who this might be right for
Recurrent Anaplastic AstrocytomaRecurrent Anaplastic OligoastrocytomaRecurrent Anaplastic Oligodendroglioma+4 more
City of Hope Medical Center 18
Early research (Phase 1)Ended earlyNCT01954030
What this trial is testing

Phase 1/2 CTO + Bevacizumab for Recurrent Glioma Post-Bevacizumab Failure

Who this might be right for
Malignant Glioma (WHO Grade III or IV)
Annick Desjardins 17
Early research (Phase 1)Looking for participantsNCT06964737
What this trial is testing

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

Who this might be right for
Recurrent Malignant GliomaRecurrent WHO Grade 3 GliomaRecurrent WHO Grade 4 Glioma+3 more
Ohio State University Comprehensive Cancer Center 30
Early research (Phase 1)Looking for participantsNCT06253234
What this trial is testing

Safety and Efficacy Study for DC Vaccine in Recurrent or Progressive High-grade Gliomas

Who this might be right for
WHO Grade III GliomasWHO Grade IV Gliomas
Beijing Tiantan Hospital 12
Large-scale testing (Phase 3)Active Not RecruitingNCT04576117
What this trial is testing

Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Who this might be right for
Recurrent Low Grade AstrocytomaRecurrent WHO Grade 2 GliomaRefractory Low Grade Astrocytoma+2 more
National Cancer Institute (NCI) 300
Not applicableNo Longer AvailableNCT02755987
What this trial is testing

Expanded Access to ANG1005 for Individual Patients

Who this might be right for
Anaplastic AstrocytomaAnaplastic OligodendrogliomaBreast Cancer With Recurrent Brain Metastases+1 more
Angiochem Inc
Testing effectiveness (Phase 2)Study completedNCT02343406
What this trial is testing

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas

Who this might be right for
Glioblastoma
AbbVie 266
Very early researchEnded earlyNCT03927274
What this trial is testing

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

Who this might be right for
Glioma of Brain
H. Lee Moffitt Cancer Center and Research Institute 3
Testing effectiveness (Phase 2)Study completedNCT01817751
What this trial is testing

Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma

Who this might be right for
GlioblastomaRecurrent Adult Brain NeoplasmMalignant Glioma+1 more
Virginia Commonwealth University 47
Early research (Phase 1)Ended earlyNCT01989052
What this trial is testing

Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma

Who this might be right for
Malignant Glioma (WHO Grade III or IV)
Annick Desjardins 9
Early research (Phase 1)Active Not RecruitingNCT04573140
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

Who this might be right for
Adult GlioblastomaHigh Grade GliomaWHO Grade III or IV Malignant Glioma
University of Florida 28
Early research (Phase 1)Active Not RecruitingNCT06410248
What this trial is testing

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent WHO Grade 2 GliomaRecurrent WHO Grade 3 Glioma+1 more
Northwestern University 30
Early research (Phase 1)Looking for participantsNCT06666712
What this trial is testing

Chronic CED of TPT for Recurrent Malignant Glioma

Who this might be right for
Brain Tumor, RecurrentMalignant Glioma (WHO Grade III or IV)IDH1/IDH2 Mutation
Jeffrey N. Bruce 6
Early research (Phase 1)Ended earlyNCT04047303
What this trial is testing

CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma

Who this might be right for
AstrocytomaGlioblastoma
Celgene 20
Very early researchWithdrawnNCT03193463
What this trial is testing

Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy

Who this might be right for
Glioma
Michael Vogelbaum, MD, PhD
Early research (Phase 1)Active Not RecruitingNCT03389230
What this trial is testing

Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma

Who this might be right for
GlioblastomaMalignant GliomaRecurrent Glioma+2 more
City of Hope Medical Center 29
Early research (Phase 1)Study completedNCT01967758
What this trial is testing

Phase I Study of Safety and Immunogenicity of ADU-623

Who this might be right for
Astrocytic TumorsGlioblastoma MultiformeAnaplastic Astrocytoma+1 more
Providence Health & Services 11
Early research (Phase 1)Active Not RecruitingNCT03749187
What this trial is testing

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

Who this might be right for
GlioblastomaIDH1 Gene MutationIDH2 Gene Mutation+7 more
University of California, San Francisco 78
Very early researchEnded earlyNCT02500459
What this trial is testing

Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection

Who this might be right for
Brain TumorHigh Grade Glioma
Michael Vogelbaum, MD, PhD 9
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