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Results for “Recurrent WHO Grade 4 Glioma”

31 trials

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Showing 20 of 31 results

Testing effectiveness (Phase 2)Looking for participantsNCT06444412
What this trial is testing

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

Who this might be right for
WHO Grade 3 GliomaWHO Grade 4 Glioma
Mayo Clinic 25
Testing effectiveness (Phase 2)Looking for participantsNCT05765812
What this trial is testing

Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeAstrocytoma, Grade III
Debiopharm International SA 116
Early research (Phase 1)Not Yet RecruitingNCT07422363
What this trial is testing

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent GliosarcomaRecurrent WHO Grade 4 Glioma
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)WithdrawnNCT03973879
What this trial is testing

Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma
Darell Bigner
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Early research (Phase 1)Not Yet RecruitingNCT07385846
What this trial is testing

Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency

Who this might be right for
GlioblastomaMismatch Repair Deficiency
Jennifer Leddon 8
Very early researchActive Not RecruitingNCT05182905
What this trial is testing

AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients

Who this might be right for
GlioblastomaGliomaGlioblastoma Multiforme+1 more
Nader Sanai 97
Testing effectiveness (Phase 2)Looking for participantsNCT06160206
What this trial is testing

Retifanlimab with Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

Who this might be right for
Recurrent GlioblastomaRecurrent WHO Grade 4 Glioma
Academic and Community Cancer Research United 134
Testing effectiveness (Phase 2)Study completedNCT01738646
What this trial is testing

Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients

Who this might be right for
Recurrent Glioblastoma MultiformeMalignant GliomaAdult Brain Tumor
Duke University 48
Early research (Phase 1)Looking for participantsNCT06482905
What this trial is testing

Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma.

Who this might be right for
High-grade GliomaWHO Grade Ⅳ Glioma
Tcelltech Inc. 52
Early research (Phase 1)Study completedNCT01491893
What this trial is testing

PVSRIPO for Recurrent Glioblastoma (GBM)

Who this might be right for
GBMGlioblastomaGlioma+1 more
Istari Oncology, Inc. 61
Testing effectiveness (Phase 2)Study completedNCT02986178
What this trial is testing

Lerapolturev in Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma
Istari Oncology, Inc. 121
Early research (Phase 1)Study completedNCT03615404
What this trial is testing

Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma

Who this might be right for
GlioblastomaMalignant GliomaMedulloblastoma Recurrent+3 more
Gary Archer Ph.D. 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT04145115
What this trial is testing

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 4Diffuse GliomaGlioblastoma, IDH-Wildtype+1 more
National Cancer Institute (NCI) 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT01903330
What this trial is testing

ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme

Who this might be right for
GlioblastomaGliosarcoma
Epitopoietic Research Corporation 84
Testing effectiveness (Phase 2)Ended earlyNCT04915404
What this trial is testing

Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV)

Who this might be right for
Recurrent Glioblastoma Multiforme
WPD Pharmaceuticals Sp. z o.o. 5
Early research (Phase 1)Looking for participantsNCT06410248
What this trial is testing

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent WHO Grade 2 GliomaRecurrent WHO Grade 3 Glioma+1 more
Northwestern University 30
Early research (Phase 1)Looking for participantsNCT06964737
What this trial is testing

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

Who this might be right for
Recurrent Malignant GliomaRecurrent WHO Grade 3 GliomaRecurrent WHO Grade 4 Glioma+3 more
Ohio State University Comprehensive Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT05859334
What this trial is testing

Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment

Who this might be right for
Recurrent GliomaRecurrent WHO Grade 2 GliomaRecurrent WHO Grade 3 Glioma+1 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Study completedNCT01240460
What this trial is testing

Exploratory Study of XL765 (SAR245409) or XL147 (SAR245408) in Subjects With Recurrent Glioblastoma Who Are Candidates for Surgical Resection

Who this might be right for
GlioblastomaAstrocytoma, Grade IV
Sanofi 40
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