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Results for “Recurrent WHO Grade 4 Glioma”

34 trials

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Showing 20 of 34 results

Very early researchActive Not RecruitingNCT05182905
What this trial is testing

AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients

Who this might be right for
GlioblastomaGliomaGlioblastoma Multiforme+1 more
Nader Sanai 97
Early research (Phase 1)Not Yet RecruitingNCT07385846
What this trial is testing

Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency

Who this might be right for
GlioblastomaMismatch Repair Deficiency
Jennifer Leddon 8
Testing effectiveness (Phase 2)Study completedNCT00104091
What this trial is testing

Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors

Who this might be right for
Glioblastoma Multiforme
Teva Branded Pharmaceutical Products R&D, Inc. 56
Not applicableActive Not RecruitingNCT07832448
What this trial is testing

Microsurgical Resection Combined With Photodynamic Therapy for Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma (WHO-Grade IV Glioma)
Yonggao Mou 10
Testing effectiveness (Phase 2)Looking for participantsNCT06160206
What this trial is testing

Retifanlimab with Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

Who this might be right for
Recurrent GlioblastomaRecurrent WHO Grade 4 Glioma
Academic and Community Cancer Research United 134
Testing effectiveness (Phase 2)UnknownNCT01903330
What this trial is testing

ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme

Who this might be right for
GlioblastomaGliosarcoma
Epitopoietic Research Corporation 84
Testing effectiveness (Phase 2)Ended earlyNCT04915404
What this trial is testing

Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV)

Who this might be right for
Recurrent Glioblastoma Multiforme
WPD Pharmaceuticals Sp. z o.o. 5
Early research (Phase 1)Study completedNCT03615404
What this trial is testing

Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma

Who this might be right for
GlioblastomaMalignant GliomaMedulloblastoma Recurrent+3 more
Gary Archer Ph.D. 11
Early research (Phase 1)Not Yet RecruitingNCT07422363
What this trial is testing

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent GliosarcomaRecurrent WHO Grade 4 Glioma
National Cancer Institute (NCI) 30
Early research (Phase 1)Looking for participantsNCT07755397
What this trial is testing

First in Human Multicenter Open Name Dose-increase, Consolidation Method to Study Safety Drug-level in Blood & Drug Metabolism Clinical Activity of Oral JBI-778 in Lung Cancer Patients With, Without Brain Metastasis IDH Mutated WHO Grade 3,4 Recurrent Glioma, Salivary Glands Tumor

Who this might be right for
NSCLC Patients With EGFR Activating MutationAdenoid Cystic Carcinoma MetastaticAdenoid Cystic Carcinoma of the Head and Neck
Jubilant Therapeutics India Limited 30
Early research (Phase 1)Study completedNCT01491893
What this trial is testing

PVSRIPO for Recurrent Glioblastoma (GBM)

Who this might be right for
GBMGlioblastomaGlioma+1 more
Istari Oncology, Inc. 61
Early research (Phase 1)Looking for participantsNCT07560865
What this trial is testing

First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma

Who this might be right for
AstrocytomaGlioblastomaProgressive Disease
Masonic Cancer Center, University of Minnesota 9
Testing effectiveness (Phase 2)Looking for participantsNCT06444412
What this trial is testing

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

Who this might be right for
WHO Grade 3 GliomaWHO Grade 4 Glioma
Mayo Clinic 25
Testing effectiveness (Phase 2)Study completedNCT01738646
What this trial is testing

Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients

Who this might be right for
Recurrent Glioblastoma MultiformeMalignant GliomaAdult Brain Tumor
Duke University 48
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Testing effectiveness (Phase 2)Study completedNCT03291314
What this trial is testing

Clinical Trial on the Combination of Avelumab and Axitinib for the Treatment of Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma (WHO-Grade IV Glioma)
Universitair Ziekenhuis Brussel 52
Testing effectiveness (Phase 2)Active Not RecruitingNCT04145115
What this trial is testing

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 4Diffuse GliomaGlioblastoma, IDH-Wildtype+1 more
National Cancer Institute (NCI) 37
Large-scale testing (Phase 3)Looking for participantsNCT07100730
What this trial is testing

Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma

Who this might be right for
Neoplastic DiseaseGlioblastomaGlioblastoma (GBM)+3 more
Telix Pharmaceuticals (Innovations) Pty Limited 50
Testing effectiveness (Phase 2)WithdrawnNCT03973879
What this trial is testing

Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma
Darell Bigner
Early research (Phase 1)Looking for participantsNCT06482905
What this trial is testing

Safety and Efficacy Study of TX103 CAR-T Cell Therapy for Recurrent or Progressive Grade 4 Glioma.

Who this might be right for
High-grade GliomaWHO Grade Ⅳ Glioma
Tcelltech Inc. 52
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