Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Recurrent WHO Grade 4 Glioma”

30 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 30 results

Early research (Phase 1)Study completedNCT01491893
What this trial is testing

PVSRIPO for Recurrent Glioblastoma (GBM)

Who this might be right for
GBMGlioblastomaGlioma+1 more
Istari Oncology, Inc. 61
Early research (Phase 1)Study completedNCT03615404
What this trial is testing

Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma

Who this might be right for
GlioblastomaMalignant GliomaMedulloblastoma Recurrent+3 more
Gary Archer Ph.D. 11
Early research (Phase 1)Active Not RecruitingNCT06410248
What this trial is testing

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent WHO Grade 2 GliomaRecurrent WHO Grade 3 Glioma+1 more
Northwestern University 30
Testing effectiveness (Phase 2)Study completedNCT02986178
What this trial is testing

Lerapolturev in Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma
Istari Oncology, Inc. 121
Testing effectiveness (Phase 2)Looking for participantsNCT06444412
What this trial is testing

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

Who this might be right for
WHO Grade 3 GliomaWHO Grade 4 Glioma
Mayo Clinic 25
Early research (Phase 1)Not Yet RecruitingNCT07385846
What this trial is testing

Pilot Study of Navigated Focused Ultrasound and Pembrolizumab in the Treatment of Recurrent WHO Grade 4 IDH-Wildtype Glioblastoma With Mismatch Repair Deficiency

Who this might be right for
GlioblastomaMismatch Repair Deficiency
Jennifer Leddon 8
Testing effectiveness (Phase 2)Looking for participantsNCT06160206
What this trial is testing

Retifanlimab with Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

Who this might be right for
Recurrent GlioblastomaRecurrent WHO Grade 4 Glioma
Academic and Community Cancer Research United 134
Testing effectiveness (Phase 2)Ended earlyNCT04915404
What this trial is testing

Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV)

Who this might be right for
Recurrent Glioblastoma Multiforme
WPD Pharmaceuticals Sp. z o.o. 5
Very early researchActive Not RecruitingNCT05182905
What this trial is testing

AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients

Who this might be right for
GlioblastomaGliomaGlioblastoma Multiforme+1 more
Nader Sanai 97
Early research (Phase 1)Looking for participantsNCT05460507
What this trial is testing

Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment

Who this might be right for
Glioma
Plus Therapeutics 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07386002
What this trial is testing

The GLIOMAX Study: MT027 Allogeneic CAR-T for Recurrent Glioma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
T-MAXIMUM Pharmaceutical Inc 40
Testing effectiveness (Phase 2)Looking for participantsNCT05765812
What this trial is testing

Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeAstrocytoma, Grade III
Debiopharm International SA 116
Testing effectiveness (Phase 2)Study completedNCT02343406
What this trial is testing

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas

Who this might be right for
Glioblastoma
AbbVie 266
Testing effectiveness (Phase 2)Study completedNCT01738646
What this trial is testing

Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients

Who this might be right for
Recurrent Glioblastoma MultiformeMalignant GliomaAdult Brain Tumor
Duke University 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT01903330
What this trial is testing

ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme

Who this might be right for
GlioblastomaGliosarcoma
Epitopoietic Research Corporation 84
Early research (Phase 1)Looking for participantsNCT06253234
What this trial is testing

Safety and Efficacy Study for DC Vaccine in Recurrent or Progressive High-grade Gliomas

Who this might be right for
WHO Grade III GliomasWHO Grade IV Gliomas
Beijing Tiantan Hospital 12
Early research (Phase 1)Study completedNCT01240460
What this trial is testing

Exploratory Study of XL765 (SAR245409) or XL147 (SAR245408) in Subjects With Recurrent Glioblastoma Who Are Candidates for Surgical Resection

Who this might be right for
GlioblastomaAstrocytoma, Grade IV
Sanofi 40
Early research (Phase 1)Not Yet RecruitingNCT07422363
What this trial is testing

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent GliosarcomaRecurrent WHO Grade 4 Glioma
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Study completedNCT03291314
What this trial is testing

Clinical Trial on the Combination of Avelumab and Axitinib for the Treatment of Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma (WHO-Grade IV Glioma)
Universitair Ziekenhuis Brussel 52
Testing effectiveness (Phase 2)WithdrawnNCT03973879
What this trial is testing

Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma
Darell Bigner
Load More Results