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Results for “Recurrent and Refractory Solid Tumors”

435 trials

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Showing 20 of 435 results

Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Testing effectiveness (Phase 2)Study completedNCT00004078
What this trial is testing

Irinotecan in Treating Children With Refractory Solid Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+18 more
Children's Oncology Group 181
Testing effectiveness (Phase 2)Study completedNCT01445080
What this trial is testing

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

Who this might be right for
Blastic PhaseChildhood Acute Promyelocytic Leukemia With PML-RARAChildhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive+7 more
National Cancer Institute (NCI) 70
Early research (Phase 1)Study completedNCT00929903
What this trial is testing

Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment

Who this might be right for
Childhood Central Nervous System ChoriocarcinomaChildhood Central Nervous System Embryonal TumorChildhood Central Nervous System Germ Cell Tumor+10 more
National Cancer Institute (NCI) 55
Early research (Phase 1)Study completedNCT00039052
What this trial is testing

Intravenous Interleukin-4 PE38KDEL Cytotoxin in Treating Patients With Recurrent or Metastatic Kidney Cancer, Non-Small Cell Lung Cancer, or Breast Cancer

Who this might be right for
Breast CancerKidney CancerLung Cancer
Neurocrine Biosciences
Testing effectiveness (Phase 2)Looking for participantsNCT03934372
What this trial is testing

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

Who this might be right for
Acute Myeloid LeukemiaAccelerated Phase Chronic Myeloid LeukemiaBlast Phase Chronic Myeloid Leukemia+6 more
Incyte Biosciences International Sàrl 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Testing effectiveness (Phase 2)Study completedNCT00003406
What this trial is testing

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+4 more
Cancer Treatment Centers of America 30
Early research (Phase 1)Looking for participantsNCT05410717
What this trial is testing

CLDN6/GPC3/Mesothelin/AXL-CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
Stage IV Ovarian CancerTestis Cancer, RefractoryEndometrial Cancer Recurrent+1 more
Second Affiliated Hospital of Guangzhou Medical University 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT05052255
What this trial is testing

RVU120 (SEL120) in Patients with Relapse/Refractory Metastatic or Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Ryvu Therapeutics SA 120
Early research (Phase 1)Study completedNCT00042900
What this trial is testing

Pyroxamide in Treating Patients With Advanced Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+5 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Looking for participantsNCT06865664
What this trial is testing

FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma

Who this might be right for
Rhabdomyosarcoma
National Cancer Institute (NCI) 50
Early research (Phase 1)Looking for participantsNCT05631886
What this trial is testing

Combination of CAR-DC Vaccine and ICIs in Malignant Tumors

Who this might be right for
Solid Tumor, AdultLymphomaEphA2 Overexpression+4 more
Chinese PLA General Hospital 10
Testing effectiveness (Phase 2)Ended earlyNCT03690869
What this trial is testing

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Who this might be right for
Relapsed Solid TumorRefractory Solid TumorRelapsed Central Nervous System Tumor+3 more
Regeneron Pharmaceuticals 57
Early research (Phase 1)Study completedNCT00101270
What this trial is testing

Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Diffuse Large Cell Lymphoma+26 more
National Cancer Institute (NCI) 24
Early research (Phase 1)Study completedNCT00609141
What this trial is testing

IMC-A12 in Treating Young Patients With Relapsed or Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor or Other Solid Tumor

Who this might be right for
Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorUnspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 34
Early research (Phase 1)Study completedNCT00019656
What this trial is testing

Perifosine in Treating Patients With Refractory Solid Tumors or Hematologic Cancer

Who this might be right for
LeukemiaLymphomaMyelodysplastic Syndromes+2 more
National Cancer Institute (NCI)
Very early researchActive Not RecruitingNCT06572956
What this trial is testing

Clinical Study on the Safety and Efficacy of CAR-T/CAR-NK Cells in the Treatment of Recurrent Refractory or Unresectable Solid Tumors

Who this might be right for
Safety and Efficacy of Cellular Drugs, Objective Response Rate of Subjects, Etc
The Second Hospital of Shandong University 10
Early research (Phase 1)Study completedNCT00003144
What this trial is testing

Chemotherapy and Amifostine in Treating Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Drug/Agent Toxicity by Tissue/OrganUnspecified Adult Solid Tumor, Protocol Specific
NYU Langone Health 44
Early research (Phase 1)Study completedNCT02225002
What this trial is testing

Phase 1, Open-Label, Dose-Escalation Study of CP-870,893 in Patients With Solid Tumors

Who this might be right for
Advanced Solid Tumors
Abramson Cancer Center at Penn Medicine
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