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Results for “Recurrent and Refractory Solid Tumors”

451 trials

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Showing 20 of 451 results

Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Early research (Phase 1)Study completedNCT05990920
What this trial is testing

Study of Allogeneic Blood-derived Natural Killer Cells to Evaluate Safety and Tolerability in Cancer Refractory to Conventional Therapy

Who this might be right for
Pathologically Confirmed Cancer Refractory to Conventional TherapyRefractory CancerMetastatic Cancer+5 more
NKGen Biotech, Inc. 6
Early research (Phase 1)Ended earlyNCT02668770
What this trial is testing

Ipilimumab (Immunotherapy) and MGN1703 (TLR Agonist) in Patients With Advanced Solid Malignancies

Who this might be right for
Advanced CancersMelanoma
M.D. Anderson Cancer Center 28
Testing effectiveness (Phase 2)Ended earlyNCT02100007
What this trial is testing

ME-344 Given in Combination With Hycamtin® in Patients With Solid Tumors

Who this might be right for
Solid Tumors
MEI Pharma, Inc. 46
Not applicableLooking for participantsNCT04515810
What this trial is testing

Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning

Who this might be right for
Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmRecurrent Hematologic Malignancy+1 more
Fred Hutchinson Cancer Center 400
Early research (Phase 1)Study completedNCT00083213
What this trial is testing

Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Who this might be right for
Cancer
Regeneron Pharmaceuticals 25
Testing effectiveness (Phase 2)Study completedNCT03526250
What this trial is testing

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more
National Cancer Institute (NCI) 23
Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Early research (Phase 1)Study completedNCT03941262
What this trial is testing

Safety of SNK01 in Subjects With Pathologically Confirmed Metastatic and/or Unresectable Cancer Refractory to Conventional Therapy

Who this might be right for
Refractory CancerMetastatic CancerRecurrent Cancer+4 more
NKGen Biotech, Inc. 27
Early research (Phase 1)Study completedNCT00003555
What this trial is testing

Paclitaxel Plus Chemoprotection With Amifostine in Treating Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
State University of New York - Upstate Medical University 20
Testing effectiveness (Phase 2)Study completedNCT02304458
What this trial is testing

Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

Who this might be right for
Metastatic MelanomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorRecurrent Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 140
Testing effectiveness (Phase 2)Looking for participantsNCT04870944
What this trial is testing

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Who this might be right for
Diffuse Midline Glioma, H3 K27-AlteredMetastatic Malignant Neoplasm in the Central Nervous SystemRecurrent Diffuse Intrinsic Pontine Glioma+7 more
Children's Oncology Group 63
Early research (Phase 1)WithdrawnNCT04498520
What this trial is testing

Abexinostat, Palbociclib, and Fulvestrant for the Treatment of Breast or Gynecologic Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+32 more
Pamela Munster
Not applicableStudy completedNCT00890435
What this trial is testing

Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical Trial

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaUnspecified Adult Solid Tumor, Protocol Specific+1 more
Children's Oncology Group 53
Early research (Phase 1)Study completedNCT01709435
What this trial is testing

Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Recurrent Malignant Solid NeoplasmRecurrent MelanomaRecurrent Primary Central Nervous System Neoplasm+4 more
National Cancer Institute (NCI) 41
Testing effectiveness (Phase 2)Active Not RecruitingNCT04195555
What this trial is testing

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Recurrent EpendymomaRecurrent Ewing SarcomaRecurrent Hepatoblastoma+30 more
National Cancer Institute (NCI) 3
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Early research (Phase 1)UnknownNCT05650580
What this trial is testing

TR115 in Patients With Relapsed / Refractory Non-Hodgkin's Lymphoma or Advanced Solid Tumors

Who this might be right for
Non-Hodgkin's Lymphoma, RelapsedNon-Hodgkin's Lymphoma RefractoryAdvanced Solid Tumor
Tarapeutics Science Inc. 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT03834961
What this trial is testing

Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia

Who this might be right for
Central Nervous System NeoplasmInfantile FibrosarcomaRecurrent Acute Leukemia+2 more
Children's Oncology Group 33
Early research (Phase 1)Study completedNCT03323034
What this trial is testing

Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma

Who this might be right for
Recurrent LymphomaRecurrent Malignant Solid NeoplasmRecurrent Primary Central Nervous System Neoplasm+3 more
Children's Oncology Group 30
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