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Results for “Recurrent or Progressive High-grade Glioma”

86 trials

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Showing 20 of 86 results

Testing effectiveness (Phase 2)Study completedNCT00004147
What this trial is testing

COL-3 in Treating Patients With Progressive or Recurrent Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
New Approaches to Brain Tumor Therapy Consortium
Testing effectiveness (Phase 2)Study completedNCT00003616
What this trial is testing

Irinotecan in Treating Patients With Progressive or Recurrent Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Testing effectiveness (Phase 2)Study completedNCT00381797
What this trial is testing

Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma

Who this might be right for
Childhood Cerebral Anaplastic AstrocytomaChildhood OligodendrogliomaChildhood Spinal Cord Neoplasm+3 more
National Cancer Institute (NCI) 97
Testing effectiveness (Phase 2)Ended earlyNCT00074334
What this trial is testing

TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 3
Very early researchEnded earlyNCT03927274
What this trial is testing

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

Who this might be right for
Glioma of Brain
H. Lee Moffitt Cancer Center and Research Institute 3
Testing effectiveness (Phase 2)Study completedNCT00041587
What this trial is testing

Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma

Who this might be right for
Malignant GliomaGlioblastoma MultiformeAnaplastic Astrocytoma+1 more
INSYS Therapeutics Inc 80
Testing effectiveness (Phase 2)Study completedNCT00087061
What this trial is testing

Gimatecan in Treating Patients With Recurrent or Progressive Primary Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Jonsson Comprehensive Cancer Center
Early research (Phase 1)Looking for participantsNCT06815029
What this trial is testing

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

Who this might be right for
Recurrent Astrocytoma, IDH-Mutant, Grade 3Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma
City of Hope Medical Center 27
Testing effectiveness (Phase 2)Study completedNCT02858895
What this trial is testing

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Who this might be right for
GlioblastomaGrade IV AstrocytomaGlioblastoma Multiforme+1 more
Medicenna Therapeutics, Inc. 47
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07567469
What this trial is testing

A Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressive High-Grade Glioma or Posterior Fossa-A Ependymoma

Who this might be right for
High-Grade Glioma (HGG)Posterior Fossa-A Ependymoma
Regeneron Pharmaceuticals 120
Testing effectiveness (Phase 2)Study completedNCT00012038
What this trial is testing

Chemotherapy in Treating Patients With Progressive or Recurrent Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
New Approaches to Brain Tumor Therapy Consortium
Early research (Phase 1)Looking for participantsNCT07664176
What this trial is testing

NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors

Who this might be right for
Diffuse Midline Glioma or Diffuse Intrinsic Pontine GliomaHigh Grade GliomasMedulloblastoma Recurrent+3 more
Children's National Research Institute 30
Early research (Phase 1)Study completedNCT00022360
What this trial is testing

Taurolidine in Treating Patients With Recurrent or Progressive Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Study completedNCT00003241
What this trial is testing

Phenylacetate in Treating Children With Recurrent or Progressive Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Texas Children's Cancer Center
Testing effectiveness (Phase 2)Study completedNCT00823797
What this trial is testing

Bendamustine Hydrochloride in Treating Patients With Recurrent or Progressive Anaplastic Glioma

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic OligodendrogliomaAdult Giant Cell Glioblastoma+3 more
University of Washington 45
Testing effectiveness (Phase 2)UnknownNCT00004204
What this trial is testing

Temozolomide in Treating Patients With Recurrent or Progressive Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Herbert Irving Comprehensive Cancer Center
Early research (Phase 1)Looking for participantsNCT07061626
What this trial is testing

Determine Maximum Tolerated Dose, Safety, and Tolerability of Rhenium (186Re) in Pediatric Recurrent, Refractory or Progressive Ependymoma and High-Grade Glioma

Who this might be right for
EpendymomaHigh Grade Gliomas
Cerenome 56
Testing effectiveness (Phase 2)Study completedNCT00005859
What this trial is testing

Tipifarnib in Treating Patients With Recurrent or Progressive Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 136
Testing effectiveness (Phase 2)Study completedNCT00045110
What this trial is testing

Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic OligodendrogliomaAdult Giant Cell Glioblastoma+6 more
National Cancer Institute (NCI) 136
Very early researchWithdrawnNCT03193463
What this trial is testing

Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy

Who this might be right for
Glioma
Michael Vogelbaum, MD, PhD
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