Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Recurrent or Progressive High-grade Glioma”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Early research (Phase 1)Looking for participantsNCT06660056
What this trial is testing

A Phase I Clinical Study of Intratumoral Injection GC001 in Patient With Recurrent or Progressive Gliomas

Who this might be right for
High-grade Gliomas
GONGCHU Biotechnology Co., Ltd 35
Testing effectiveness (Phase 2)Study completedNCT00070525
What this trial is testing

Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma

Who this might be right for
Childhood High-grade Cerebral AstrocytomaChildhood OligodendrogliomaRecurrent Childhood Brain Stem Glioma+5 more
National Cancer Institute (NCI) 90
Early research (Phase 1)Looking for participantsNCT04573140
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

Who this might be right for
Adult GlioblastomaHigh Grade GliomaWHO Grade III or IV Malignant Glioma
University of Florida 28
Early research (Phase 1)Looking for participantsNCT05686798
What this trial is testing

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Who this might be right for
Malignant Glioma of BrainAstrocytomaMalignant Astrocytoma+6 more
Henry Ford Health System 18
Early research (Phase 1)Study completedNCT00093613
What this trial is testing

Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic OligodendrogliomaAdult Giant Cell Glioblastoma+2 more
National Cancer Institute (NCI) 47
Early research (Phase 1)Looking for participantsNCT04254419
What this trial is testing

Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells

Who this might be right for
High Grade Glioma
Nationwide Children's Hospital 18
Testing effectiveness (Phase 2)Study completedNCT03257631
What this trial is testing

Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

Who this might be right for
Central Nervous System NeoplasmsMedulloblastoma
Celgene 53
Testing effectiveness (Phase 2)Study completedNCT00892177
What this trial is testing

Dasatinib and Bevacizumab in Treating Patients With Recurrent or Progressive High-Grade Glioma or Glioblastoma Multiforme

Who this might be right for
Glioblastoma Multiforme
Alliance for Clinical Trials in Oncology 144
Early research (Phase 1)Study completedNCT01547546
What this trial is testing

GDC-0084 in Patients With Progressive or Recurrent High-Grade Glioma

Who this might be right for
Glioblastoma, Glioma
Genentech, Inc. 29
Very early researchStudy completedNCT02278510
What this trial is testing

Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma

Who this might be right for
Malignant GliomaWHO Grade III or IV Recurrent Glioma
Michael Vogelbaum, MD, PhD 3
Early research (Phase 1)Study completedNCT02457845
What this trial is testing

HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors

Who this might be right for
Supratentorial Neoplasms, MalignantMalignant GliomaGlioblastoma+4 more
Gregory K. Friedman, MD 13
Early research (Phase 1)Study completedNCT01171469
What this trial is testing

Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor

Who this might be right for
Brain TumorGlioblastomaMedulloblastoma+2 more
Masonic Cancer Center, University of Minnesota 8
Testing effectiveness (Phase 2)Study completedNCT00795665
What this trial is testing

Bevacizumab and Carmustine in Treating Patients With Relapsed or Progressive High-Grade Glioma

Who this might be right for
Glioma
University of California, Davis 7
Early research (Phase 1)Active Not RecruitingNCT02062827
What this trial is testing

Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant Glioma

Who this might be right for
Recurrent Glioblastoma MultiformeProgressive Glioblastoma MultiformeAnaplastic Astrocytoma or Gliosarcoma
University of Alabama at Birmingham 29
Early research (Phase 1)Active Not RecruitingNCT04323046
What this trial is testing

Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

Who this might be right for
GlioblastomaMalignant GliomaRecurrent Glioblastoma+3 more
Sabine Mueller, MD, PhD 9
Early research (Phase 1)UnknownNCT00591058
What this trial is testing

Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma

Who this might be right for
Malignant GliomaGlioblastoma MultiformeGBM+2 more
TransMolecular 36
Testing effectiveness (Phase 2)Study completedNCT01051557
What this trial is testing

Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic OligodendrogliomaAdult Diffuse Astrocytoma+6 more
National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Study completedNCT00704288
What this trial is testing

Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme

Who this might be right for
Glioblastoma Multiforme
Exelixis 222
Testing effectiveness (Phase 2)Ended earlyNCT02885324
What this trial is testing

Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children

Who this might be right for
Glioblastoma MultiformeAnaplastic AstrocytomaMalignant Brain Tumor+1 more
Indiana University 4
Early research (Phase 1)Active Not RecruitingNCT03598244
What this trial is testing

Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

Who this might be right for
Recurrent Diffuse Intrinsic Pontine GliomaRecurrent Malignant GliomaRecurrent Medulloblastoma+5 more
National Cancer Institute (NCI) 41
Next Page