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Results for “Recurrent or Progressive Low-grade Glioma”

21 trials

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Showing 20 of 21 results

Large-scale testing (Phase 3)Active Not RecruitingNCT00978458
What this trial is testing

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Who this might be right for
Brain and Central Nervous System TumorsNeurotoxicity
Eastern Cooperative Oncology Group 540
Testing effectiveness (Phase 2)Study completedNCT02197637
What this trial is testing

Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma

Who this might be right for
Low-Grade Glioma
Centre Oscar Lambret 39
Early research (Phase 1)Study completedNCT00107458
What this trial is testing

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

Who this might be right for
Brain and Central Nervous System TumorsUnspecified Childhood Solid Tumor, Protocol Specific
Children's Oncology Group 26
Testing effectiveness (Phase 2)Ended earlyNCT01338857
What this trial is testing

Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas

Who this might be right for
neurofibromatosis1 (NF1)Recurrent or Progressive Optic Pathway Gliomas (OPG)Recurrent or Progressive Low-grade Glioma
NYU Langone Health 12
Testing effectiveness (Phase 2)Study completedNCT00782626
What this trial is testing

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

Who this might be right for
GliomaLow-grade GliomaAstrocytoma
Dana-Farber Cancer Institute 23
Early research (Phase 1)Study completedNCT00100880
What this trial is testing

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+23 more
National Cancer Institute (NCI) 45
Testing effectiveness (Phase 2)Study completedNCT00066248
What this trial is testing

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Who this might be right for
Brain TumorCentral Nervous System TumorsCachexia+5 more
University of South Florida 70
Testing effectiveness (Phase 2)WithdrawnNCT05222165
What this trial is testing

Study With Infigratinib in Subjects With Advanced Solid and CNS Tumors or Recurrent or Progressive Low-Grade Glioma With Selected FGFR1-3 Alterations

Who this might be right for
Advanced Solid TumorCNS TumorRecurrent WHO Grade II Glioma
Helsinn Healthcare SA
Not applicableLooking for participantsNCT07506239
What this trial is testing

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

Who this might be right for
Low-grade GliomaRecurrent Low Grade GliomaLow Grade Glioma of Brain+1 more
University of California, San Francisco 40
Early research (Phase 1)Study completedNCT02423525
What this trial is testing

Safety Study of Afatinib for Brain Cancer

Who this might be right for
Brain Cancer
Santosh Kesari 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT04201457
What this trial is testing

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Who this might be right for
Low Grade Glioma (LGG) of Brain With BRAF AberrationHigh Grade Glioma (HGG) of the Brain With BRAF AberrationLow Grade Glioma of Brain With Neurofibromatosis Type 1
Pediatric Brain Tumor Consortium 57
Not applicableStudy completedNCT00276640
What this trial is testing

Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade Gliomas

Who this might be right for
Primary Central Nervous System Neoplasms
Societe Internationale d'Oncologie Pediatrique 3,417
Large-scale testing (Phase 3)Active Not RecruitingNCT04576117
What this trial is testing

Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Who this might be right for
Recurrent Low Grade AstrocytomaRecurrent WHO Grade 2 GliomaRefractory Low Grade Astrocytoma+2 more
National Cancer Institute (NCI) 300
Testing effectiveness (Phase 2)Looking for participantsNCT04775485
What this trial is testing

Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

Who this might be right for
Low-grade GliomaAdvanced Solid Tumor
Day One Biopharmaceuticals, Inc. 141
Testing effectiveness (Phase 2)Study completedNCT01734512
What this trial is testing

PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children

Who this might be right for
Pediatric Recurrent Progressive Low-grade GliomasPediatric Progressive Low-grade Gliomas
University of California, San Francisco 65
Testing effectiveness (Phase 2)Study completedNCT01497860
What this trial is testing

Vinorelbine for Children With Progressive or Recurrent Low-grade Gliomas

Who this might be right for
Low-grade Glioma
Eugene Hwang 13
Testing effectiveness (Phase 2)Study completedNCT03557359
What this trial is testing

Nivolumab for Recurrent or Progressive IDH Mutant Gliomas

Who this might be right for
Gliomas
Fabio Iwamoto, MD 35
Early research (Phase 1)Study completedNCT00098761
What this trial is testing

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 42
Early research (Phase 1)Looking for participantsNCT07664176
What this trial is testing

NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors

Who this might be right for
Diffuse Midline Glioma or Diffuse Intrinsic Pontine GliomaHigh Grade GliomasMedulloblastoma Recurrent+3 more
Children's National Research Institute 30
Testing effectiveness (Phase 2)Study completedNCT00381797
What this trial is testing

Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma

Who this might be right for
Childhood Cerebral Anaplastic AstrocytomaChildhood OligodendrogliomaChildhood Spinal Cord Neoplasm+3 more
National Cancer Institute (NCI) 97
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