Early research (Phase 1)Study completedNCT01547546What this trial is testingGDC-0084 in Patients With Progressive or Recurrent High-Grade GliomaWho this might be right forGlioblastoma, Glioma Genentech, Inc. 29
Early research (Phase 1)Active Not RecruitingNCT03598244What this trial is testingSavolitinib in Treating Patients With Recurrent or Refractory Primary CNS TumorsWho this might be right forRecurrent Diffuse Intrinsic Pontine GliomaRecurrent Malignant GliomaRecurrent Medulloblastoma+5 more National Cancer Institute (NCI) 41
Testing effectiveness (Phase 2)Study completedNCT01051557What this trial is testingTemsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant GliomaWho this might be right forAdult Anaplastic AstrocytomaAdult Anaplastic OligodendrogliomaAdult Diffuse Astrocytoma+6 more National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Study completedNCT00293423What this trial is testingGP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Recurrent or Progressive GliomaWho this might be right forBrain and Central Nervous System Tumors University of California, San Francisco 96
Very early researchWithdrawnNCT03193463What this trial is testingIntratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic BiopsyWho this might be right forGlioma Michael Vogelbaum, MD, PhD
Testing effectiveness (Phase 2)UnknownNCT00683761What this trial is testing131I-TM601 in Adults With Recurrent Malignant GliomaWho this might be right forMalignant GliomaGlioblastoma MultiformeGBM+2 more TransMolecular 64
Early research (Phase 1)Study completedNCT01393912What this trial is testingPDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade GliomaWho this might be right forDiffuse Intrinsic Pontine GliomaProgressive or Refractory High-Grade Glioma St. Jude Children's Research Hospital 55
Testing effectiveness (Phase 2)Study completedNCT00087061What this trial is testingGimatecan in Treating Patients With Recurrent or Progressive Primary Malignant GliomaWho this might be right forBrain and Central Nervous System Tumors Jonsson Comprehensive Cancer Center
Early research (Phase 1)Looking for participantsNCT07464925What this trial is testingSafety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade GliomaWho this might be right forGlioblastoma Multiforme of BrainGliomaGlioblastoma Tetragon Biosciences Ltd 30
Testing effectiveness (Phase 2)Study completedNCT00070525What this trial is testingTipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem GliomaWho this might be right forChildhood High-grade Cerebral AstrocytomaChildhood OligodendrogliomaRecurrent Childhood Brain Stem Glioma+5 more National Cancer Institute (NCI) 90
Testing effectiveness (Phase 2)Study completedNCT02490800What this trial is testingPhase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade GliomaWho this might be right forNeoplasms Basilea Pharmaceutica 72
Testing effectiveness (Phase 2)Study completedNCT00795665What this trial is testingBevacizumab and Carmustine in Treating Patients With Relapsed or Progressive High-Grade GliomaWho this might be right forGlioma University of California, Davis 7
Testing effectiveness (Phase 2)Ended earlyNCT04985604What this trial is testingTovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid TumorsWho this might be right forMelanomaSolid TumorCRAF Gene Amplification+20 more Day One Biopharmaceuticals, Inc. 23
Early research (Phase 1)Active Not RecruitingNCT04214392What this trial is testingChimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive GlioblastomaWho this might be right forRecurrent GlioblastomaRecurrent Malignant GliomaRecurrent WHO Grade II Glioma+1 more City of Hope Medical Center 19
Testing effectiveness (Phase 2)Study completedNCT00003465What this trial is testingTemozolomide in Treating Patients With Anaplastic OligodendrogliomaWho this might be right forBrain and Central Nervous System Tumors Duke University 60
Testing effectiveness (Phase 2)Study completedNCT00381797What this trial is testingBevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade GliomaWho this might be right forChildhood Cerebral Anaplastic AstrocytomaChildhood OligodendrogliomaChildhood Spinal Cord Neoplasm+3 more National Cancer Institute (NCI) 97
Early research (Phase 1)Looking for participantsNCT07544992What this trial is testingLocoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade GliomasWho this might be right forRecurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma, IDH-Wildtype City of Hope Medical Center 24
Testing effectiveness (Phase 2)Study completedNCT00005855What this trial is testingEfaproxiral Plus Carmustine in Treating Patients With Progressive or Recurrent Malignant GliomaWho this might be right forBrain and Central Nervous System Tumors New Approaches to Brain Tumor Therapy Consortium 48
Early research (Phase 1)Looking for participantsNCT04573140What this trial is testingRNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)Who this might be right forAdult GlioblastomaHigh Grade GliomaWHO Grade III or IV Malignant Glioma University of Florida 28
Early research (Phase 1)Ended earlyNCT01009866What this trial is testingStudy of Immunotoxin, MR1-1Who this might be right forSupratentorial Malignant Brain Tumor Darell D. Bigner, MD, PhD 9