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Results for “Recurrent or Refractory Medulloblastoma”

87 trials

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Showing 20 of 87 results

Early research (Phase 1)Study completedNCT00101270
What this trial is testing

Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Diffuse Large Cell Lymphoma+26 more
National Cancer Institute (NCI) 24
Not applicableStudy completedNCT00006342
What this trial is testing

Genetic Study in Patients Receiving Treatment for Hodgkin's Disease or Childhood Brain Tumor

Who this might be right for
Brain and Central Nervous System TumorsLymphoma
Duke University 19
Large-scale testing (Phase 3)Study completedNCT00749723
What this trial is testing

Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children

Who this might be right for
Recurrent Brain TumorsSupratentorial PNETsMedulloblastomas+1 more
University Hospital, Bonn 174
Early research (Phase 1)Looking for participantsNCT04185038
What this trial is testing

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Who this might be right for
Central Nervous System TumorDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma+8 more
Seattle Children's Hospital 90
Testing effectiveness (Phase 2)Study completedNCT03213678
What this trial is testing

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+30 more
National Cancer Institute (NCI) 18
Early research (Phase 1)Study completedNCT00006368
What this trial is testing

Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerGastrointestinal Carcinoid Tumor+5 more
Novartis Pharmaceuticals 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04195555
What this trial is testing

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Recurrent EpendymomaRecurrent Ewing SarcomaRecurrent Hepatoblastoma+30 more
National Cancer Institute (NCI) 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Early research (Phase 1)Study completedNCT00030108
What this trial is testing

Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+7 more
National Institutes of Health Clinical Center (CC) 30
Not applicableLooking for participantsNCT07242963
What this trial is testing

Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study

Who this might be right for
Medulloblastoma RecurrentMedulloblastoma, Childhood, RecurrentMedulloblastoma, SHH-activated and TP53 Mutant+1 more
Mohammad H. Abu Arja 300
Testing effectiveness (Phase 2)Study completedNCT00939484
What this trial is testing

Vismodegib in Treating Patients With Recurrent or Refractory Medulloblastoma

Who this might be right for
Adult Medulloblastoma
National Cancer Institute (NCI) 31
Early research (Phase 1)Study completedNCT00004212
What this trial is testing

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsLymphomaUnspecified Childhood Solid Tumor, Protocol Specific
Daiichi Sankyo
Testing effectiveness (Phase 2)Looking for participantsNCT06607692
What this trial is testing

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

Who this might be right for
Solid Tumor CancerMedulloblastomaHigh Risk Neuroblastoma+17 more
Fundación de investigación HM 25
Testing effectiveness (Phase 2)Study completedNCT01217437
What this trial is testing

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors

Who this might be right for
Central Nervous System NeoplasmPineoblastomaRecurrent Medulloblastoma+3 more
National Cancer Institute (NCI) 108
Early research (Phase 1)Looking for participantsNCT07087002
What this trial is testing

GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults

Who this might be right for
MedulloblastomaCentral Nervous System Embryonal TumorRefractory Medulloblastoma+7 more
Stanford University 18
Early research (Phase 1)Study completedNCT00019019
What this trial is testing

Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerKidney Cancer+6 more
National Institutes of Health Clinical Center (CC) 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT04284774
What this trial is testing

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Malignant Solid NeoplasmRecurrent Adrenal Gland PheochromocytomaRecurrent Ectomesenchymoma+38 more
National Cancer Institute (NCI) 5
Early research (Phase 1)Study completedNCT01158300
What this trial is testing

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 28
Early research (Phase 1)Study completedNCT00077454
What this trial is testing

Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Previously Treated Childhood RhabdomyosarcomaRecurrent Childhood Brain TumorRecurrent Childhood Cerebellar Astrocytoma+9 more
National Cancer Institute (NCI) 95
Early research (Phase 1)Study completedNCT04023669
What this trial is testing

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

Who this might be right for
Brain TumorBrain Tumor, RecurrentBrain Tumor, Refractory+10 more
St. Jude Children's Research Hospital 21
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