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Results for “Recurrent or Refractory Solid Tumors”

318 trials

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Showing 20 of 318 results

Early research (Phase 1)Study completedNCT02451553
What this trial is testing

Afatinib Dimaleate and Capecitabine in Treating Patients With Advanced Refractory Solid Tumors, Pancreatic Cancer or Biliary Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmBile Duct CarcinomaRecurrent Malignant Solid Neoplasm+4 more
University of Washington 41
Testing effectiveness (Phase 2)Looking for participantsNCT07410494
What this trial is testing

Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
CancerBreast CancerNon-Small Cell Lung Cancer (NSCLC)+10 more
Essen Biotech 85
Testing effectiveness (Phase 2)Ended earlyNCT03993379
What this trial is testing

PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid Tumors

Who this might be right for
Solid TumorUnresectable or Metastatic Melanoma
CytomX Therapeutics 3
Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Active Not RecruitingNCT02867592
What this trial is testing

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Who this might be right for
Adrenal Cortical CarcinomaAlveolar Soft Part SarcomaCentral Nervous System Neoplasm+41 more
National Cancer Institute (NCI) 109
Early research (Phase 1)Study completedNCT00348699
What this trial is testing

AFP464 in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery

Who this might be right for
Male Breast CancerRecurrent Breast CancerRecurrent Ovarian Epithelial Cancer+7 more
National Cancer Institute (NCI) 68
Early research (Phase 1)Study completedNCT00993044
What this trial is testing

Vincristine, Escalating Doses of Irinotecan, Temozolomide and Bevacizumab (Vit-b) in Pediatric and Adolescent Patients With Recurrent or Refractory Solid Tumors of Non-hematopoietic Origin

Who this might be right for
Refractory Solid Tumors in Children
Children's Hospital Los Angeles 13
Early research (Phase 1)Study completedNCT00005021
What this trial is testing

Combination Chemotherapy With or Without Biological Therapy in Treating Patients With Refractory Solid Tumor or Lymphoma

Who this might be right for
LymphomaSmall Intestine CancerUnspecified Adult Solid Tumor, Protocol Specific
Fox Chase Cancer Center 17
Early research (Phase 1)Temporarily pausedNCT04840589
What this trial is testing

Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmRecurrent Malignant Solid NeoplasmRecurrent Platinum-Resistant Ovarian Carcinoma+1 more
National Cancer Institute (NCI) 66
Testing effectiveness (Phase 2)Ended earlyNCT04530487
What this trial is testing

Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults

Who this might be right for
Desmoplastic Small Round Cell TumorEwing Sarcoma/Peripheral Primitive Neuroectodermal TumorRecurrent Desmoplastic Small Round Cell Tumor+9 more
M.D. Anderson Cancer Center 1
Early research (Phase 1)Study completedNCT00003430
What this trial is testing

L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Head and Neck CancerUnspecified Adult Solid Tumor, Protocol Specific
Memorial Sloan Kettering Cancer Center 40
Early research (Phase 1)Study completedNCT00608361
What this trial is testing

Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery

Who this might be right for
Adult Acute Lymphoblastic Leukemia in RemissionAdult B Acute Lymphoblastic LeukemiaAdult Hepatocellular Carcinoma+82 more
National Cancer Institute (NCI) 80
Testing effectiveness (Phase 2)Looking for participantsNCT07480213
What this trial is testing

Adaptive Phase 1/2 Study of Dual-Target CAR-NK Cells in Relapsed/Refractory Small Cell Lung Cancer (SCLC)

Who this might be right for
Small Cell Lung Cancer (SCLC)Relapsed/Refractory SCLCSCLC, Extensive Stage
Beijing Biotech 60
Early research (Phase 1)Study completedNCT02628574
What this trial is testing

Phase 1 Open-label Study of TRX518 Monotherapy and TRX518 in Combination With Gemcitabine, Pembrolizumab, or Nivolumab

Who this might be right for
Solid Tumors
Leap Therapeutics, Inc. 109
Testing effectiveness (Phase 2)Study completedNCT01154816
What this trial is testing

Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
HepatoblastomaPreviously Treated Childhood RhabdomyosarcomaRecurrent Childhood Acute Lymphoblastic Leukemia+8 more
Children's Oncology Group 118
Early research (Phase 1)Ended earlyNCT00933985
What this trial is testing

Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia

Who this might be right for
Acute Leukemias of Ambiguous LineageAcute Undifferentiated LeukemiaAngioimmunoblastic T-cell Lymphoma+26 more
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Ended earlyNCT00788125
What this trial is testing

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
City of Hope Medical Center 7
Early research (Phase 1)Study completedNCT02085148
What this trial is testing

A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy

Who this might be right for
Pediatric Oncology
Bayer 62
Early research (Phase 1)WithdrawnNCT01182883
What this trial is testing

A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Brain Stem NeoplasmsGliomaPinealoma
National Cancer Institute (NCI)
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