Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Refractory / Relapsed / Progressive Systemic Sclerosis”

27 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 27 results

Early research (Phase 1)Looking for participantsNCT07104721
What this trial is testing

A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases

Who this might be right for
Systemic Lupus Erythematosus (SLE)Lupus Nephritis (LN)Systemic Sclerosis (SSc)+3 more
China Immunotech (Beijing) Biotechnology Co., Ltd. 18
Very early researchNot Yet RecruitingNCT06420154
What this trial is testing

The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus Erythematosus (SLE)Sjogren's SyndromeSystemic Sclerosis+3 more
First Affiliated Hospital of Wenzhou Medical University 9
Early research (Phase 1)Looking for participantsNCT07236801
What this trial is testing

Exploratory Clinical Study on YTS109 Cell Therapy for Autoimmune Diseases

Who this might be right for
Systemic Lupus Erythematosus (SLE)Systemic SclerosisSjogren's Syndrome (SS)+3 more
China Immunotech (Beijing) Biotechnology Co., Ltd. 18
Early research (Phase 1)Looking for participantsNCT06978647
What this trial is testing

A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases

Who this might be right for
Systemic Lupus Erythematosus (SLE)Systemic Sclerosis (SSc)Inflammatory Myopathy+5 more
China Immunotech (Beijing) Biotechnology Co., Ltd. 12
Testing effectiveness (Phase 2)Looking for participantsNCT06991114
What this trial is testing

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

Who this might be right for
Refractory Rheumatoid Arthritis (RA)Idiopathic Inflammatory Myopathies (IIMs)Systemic Sclerosis (SSc)+6 more
Artiva Biotherapeutics, Inc. 90
Early research (Phase 1)Not Yet RecruitingNCT06978738
What this trial is testing

UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusAutoimmune Hemolytic AnemiaMyasthenia Gravis+4 more
Changzhou No.2 People's Hospital 18
Early research (Phase 1)Looking for participantsNCT07315087
What this trial is testing

CAR T-cell Therapy Targeting CD19 and BCMA(QT-019C) in Patients With Relapse/Refractory Autoimmune Diseases

Who this might be right for
SLE - Systemic Lupus ErythematosusSSc-Systemic SclerosisIIM- Idiopathic Inflammatory Myopathies+3 more
Institute of Hematology & Blood Diseases Hospital, China 12
Testing effectiveness (Phase 2)Looking for participantsNCT06350110
What this trial is testing

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)

Who this might be right for
Systemic Lupus ErythematosusLupus NephritisAutoimmune Diseases+6 more
Essen Biotech 75
Not applicableLooking for participantsNCT06361745
What this trial is testing

Early Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathiesSystemic Sclerosis+2 more
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
Very early researchNot Yet RecruitingNCT06417398
What this trial is testing

Preliminary Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathiesSystemic Sclerosis+4 more
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
Not applicableActive Not RecruitingNCT07155369
What this trial is testing

UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusSystemic Sclerosis
The Affiliated Hospital of Xuzhou Medical University 18
Early research (Phase 1)Looking for participantsNCT07413341
What this trial is testing

A Clinical Study of TI-0032-III Injection in Patients With Relapsed and Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus Erythematosus (SLE)Sjogren's Syndrome (SS)Systemic Sclerosis (SSc)+2 more
Therorna 12
Not applicableLooking for participantsNCT06373081
What this trial is testing

Anti-CD19-CD3E-CAR-T Cells in Relapsed/Refractory Autoimmune Disease

Who this might be right for
Systemic Lupus Erythematosus (SLE)Sjogren's SyndromeSystemic Sclerosis+3 more
Shanghai Changzheng Hospital 6
Not applicableEnrolling By InvitationNCT05859997
What this trial is testing

Universal CAR-T Cells (BRL-301) in Relapse or Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus Erythematosus (SLE)Sjogren's SyndromeSystemic Sclerosis+3 more
Bioray Laboratories 15
Early research (Phase 1)Looking for participantsNCT07361094
What this trial is testing

Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Relapsed/Refractory Systemic Lupus ErythematosusRelapsed/Refractory Systemic SclerosisRelapsed/Refractory Idiopathic Inflammatory Myopathies+3 more
Beijing Boren Hospital 12
Early research (Phase 1)Not Yet RecruitingNCT07490275
What this trial is testing

Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Refractory/Relapsed Systemic Lupus ErythematosusRefractory / Relapsed / Progressive Systemic SclerosisRefractory / Relapsing / Progressive Inflammatory Myopathy+2 more
Institute of Hematology & Blood Diseases Hospital, China
Early research (Phase 1)Looking for participantsNCT06316076
What this trial is testing

Safety and Efficacy Study of CD19-CAR-DNT Cells in Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisIdiopathic Inflammatory Myopathies+1 more
RenJi Hospital 48
Early research (Phase 1)Looking for participantsNCT06941129
What this trial is testing

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With Relapse/Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusSystemic Sclerosis (SSc)Inflammatory Myopathy+3 more
Institute of Hematology & Blood Diseases Hospital, China 12
Very early researchLooking for participantsNCT07246096
What this trial is testing

Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Autoimmune DiseasesSystemic Lupus ErythematosusSystemic Sclerosis+3 more
Changhai Hospital 60
Not applicableNot Yet RecruitingNCT06871644
What this trial is testing

Clinical Study of CD7 CAR-T Cells for Relapsed/refractory Autoimmune Diseases

Who this might be right for
Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 18
Load More Results
9