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Results for “Refractory Acute Leukemia of Ambiguous Lineage”

66 trials

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Showing 20 of 66 results

Testing effectiveness (Phase 2)Looking for participantsNCT03128034
What this trial is testing

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia+9 more
Fred Hutchinson Cancer Center 75
Early research (Phase 1)Ended earlyNCT03198234
What this trial is testing

Use of T-allo10 in Hematopoietic Stem Cell Transplantation (HSCT) for Blood Disorders

Who this might be right for
AML - Acute Myeloid LeukemiaMDS (Myelodysplastic Syndrome)Mixed Phenotype Acute Leukemia+3 more
Roncarolo, Maria Grazia, MD 5
Testing effectiveness (Phase 2)Study completedNCT02044796
What this trial is testing

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Who this might be right for
Acute Biphenotypic Leukemiade Novo Myelodysplastic SyndromePreviously Treated Myelodysplastic Syndrome+3 more
Fred Hutchinson Cancer Center 199
Early research (Phase 1)Study completedNCT03194932
What this trial is testing

Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage

Who this might be right for
Acute Myeloid Leukemia
St. Jude Children's Research Hospital 62
Testing effectiveness (Phase 2)Looking for participantsNCT03670966
What this trial is testing

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia in Remission+9 more
Fred Hutchinson Cancer Center 30
Early research (Phase 1)Study completedNCT02212561
What this trial is testing

Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia (AML)Acute Lymphoblastic Leukemia (ALL)Myelodysplastic Syndrome (MDS)+1 more
St. Jude Children's Research Hospital 19
Testing effectiveness (Phase 2)Looking for participantsNCT07356154
What this trial is testing

Revumenib and Mezigdomide in People With Leukemia

Who this might be right for
LeukemiaAcute LeukemiaRelapse Leukemia+5 more
Memorial Sloan Kettering Cancer Center 52
Testing effectiveness (Phase 2)Study completedNCT01858740
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+15 more
Fred Hutchinson Cancer Center 20
Testing effectiveness (Phase 2)Ended earlyNCT01028716
What this trial is testing

Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Acute Biphenotypic LeukemiaAcute Erythroid Leukemia in RemissionAcute Leukemia in Remission+27 more
Fred Hutchinson Cancer Center 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT03404193
What this trial is testing

Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlastic Plasmacytoid Dendritic Cell Neoplasm+12 more
M.D. Anderson Cancer Center 235
Testing effectiveness (Phase 2)Looking for participantsNCT04065399
What this trial is testing

Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMixed Lineage Acute Leukemia+2 more
Syndax Pharmaceuticals 447
Testing effectiveness (Phase 2)Ended earlyNCT02399917
What this trial is testing

Lirilumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia

Who this might be right for
Acute Biphenotypic LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+1 more
M.D. Anderson Cancer Center 36
Testing effectiveness (Phase 2)Looking for participantsNCT02727803
What this trial is testing

Personalized NK Cell Therapy in CBT

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Lymphoblastic Leukemia+23 more
M.D. Anderson Cancer Center 100
Early research (Phase 1)Study completedNCT05326516
What this trial is testing

Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia

Who this might be right for
Relapsed/Refractory LeukemiasAcute Lymphoblastic LeukemiaAcute Lymphocytic Leukemia+3 more
Syndax Pharmaceuticals 30
Early research (Phase 1)Looking for participantsNCT05476770
What this trial is testing

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Who this might be right for
Hematologic MalignancyAMLALL+8 more
Therapeutic Advances in Childhood Leukemia Consortium 54
Testing effectiveness (Phase 2)Looking for participantsNCT07256210
What this trial is testing

Feasibility and Safety of Donor-derived NK-cell Infusions for Leukemia Relapse Prophylaxis After Hematopoietic Stem Cell Transplantation

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic T-cell LeukemiaMixed Phenotype Acute Leukemia
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 15
Early research (Phase 1)Looking for participantsNCT04872478
What this trial is testing

Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia
Meryx, Inc. 50
Early research (Phase 1)Active Not RecruitingNCT02879695
What this trial is testing

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent Mixed Phenotype Acute LeukemiaRefractory B Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 28
Testing effectiveness (Phase 2)Active Not RecruitingNCT03399773
What this trial is testing

Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

Who this might be right for
Acute Biphenotypic LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia, BCR-ABL1 Positive+3 more
Fred Hutchinson Cancer Center 31
Testing effectiveness (Phase 2)WithdrawnNCT02718755
What this trial is testing

Phase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic Malignancies

Who this might be right for
Hematologic Malignancy
M.D. Anderson Cancer Center
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