Early research (Phase 1)Study completedNCT01431664What this trial is testingAT9283 in Treating Young Patients With Relapsed or Refractory Acute LeukemiaWho this might be right forLeukemia Cancer Research UK 7
Testing effectiveness (Phase 2)Looking for participantsNCT04195633What this trial is testingDonor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological MalignanciesWho this might be right forAcute LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+16 more Fred Hutchinson Cancer Center 60
Early research (Phase 1)Looking for participantsNCT03326921What this trial is testingHA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell TransplantWho this might be right forJuvenile Myelomonocytic LeukemiaRecurrent Acute Biphenotypic LeukemiaRecurrent Acute Undifferentiated Leukemia+26 more Fred Hutchinson Cancer Center 24
Early research (Phase 1)Study completedNCT01132573What this trial is testingEntinostat and Clofarabine in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Poor-Risk Acute Lymphoblastic Leukemia or Bilineage/Biphenotypic LeukemiaWho this might be right forAcute Leukemias of Ambiguous LineagePhiladelphia Chromosome Negative Adult Precursor Acute Lymphoblastic LeukemiaRecurrent Adult Acute Lymphoblastic Leukemia+1 more National Cancer Institute (NCI) 27
Testing effectiveness (Phase 2)Looking for participantsNCT02727803What this trial is testingPersonalized NK Cell Therapy in CBTWho this might be right forAccelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Lymphoblastic Leukemia+23 more M.D. Anderson Cancer Center 100
Testing effectiveness (Phase 2)WithdrawnNCT02718755What this trial is testingPhase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic MalignanciesWho this might be right forHematologic Malignancy M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT05761171What this trial is testingRevumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory LeukemiaWho this might be right forRecurrent Acute Leukemia of Ambiguous LineageRecurrent Acute Lymphoblastic LeukemiaRecurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage+9 more Children's Oncology Group 78
Testing effectiveness (Phase 2)Ended earlyNCT02399917What this trial is testingLirilumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid LeukemiaWho this might be right forAcute Biphenotypic LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+1 more M.D. Anderson Cancer Center 36
Early research (Phase 1)Active Not RecruitingNCT04898894What this trial is testingStudy of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid LeukemiaWho this might be right forAcute Leukemia of Ambiguous Lineage in RelapseAcute Myeloid Leukemia, in RelapseRefractory Acute Leukemia of Ambiguous Lineage+1 more St. Jude Children's Research Hospital 37
Very early researchStudy completedNCT03957915What this trial is testingStudy of Escalating Doses of INA03 Administered Intravenously as Single Agent in Adult Patients With Relapse/Refractory Acute LeukemiaWho this might be right forAcute Lymphoblastic Leukemia RecurrentAcute Lymphoblastic Leukemia, in RelapseAcute Myeloid Leukemia, in Relapse+2 more Institut Paoli-Calmettes 33
Not applicableLooking for participantsNCT05794880What this trial is testingMCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG DosingWho this might be right forLeukemiaAcute Myeloid Leukemia in RemissionMyelodysplasia+10 more Medical College of Wisconsin 40
Testing effectiveness (Phase 2)Study completedNCT01858740What this trial is testingSelective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in ChildrenWho this might be right forAccelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+15 more Fred Hutchinson Cancer Center 20
Early research (Phase 1)Ended earlyNCT03198234What this trial is testingUse of T-allo10 in Hematopoietic Stem Cell Transplantation (HSCT) for Blood DisordersWho this might be right forAML - Acute Myeloid LeukemiaMDS (Myelodysplastic Syndrome)Mixed Phenotype Acute Leukemia+3 more Roncarolo, Maria Grazia, MD 5
Early research (Phase 1)Active Not RecruitingNCT05146739What this trial is testingHighest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell MembraneWho this might be right forAcute Myeloid Leukemia Post Cytotoxic TherapyMyelodysplastic Syndrome Post Cytotoxic TherapyMyeloid Leukemia Associated With Down Syndrome+6 more National Cancer Institute (NCI)
Testing effectiveness (Phase 2)WithdrawnNCT05320380What this trial is testingThe Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to TreatWho this might be right forRecurrent Acute Myeloid LeukemiaRecurrent B Acute Lymphoblastic LeukemiaRecurrent Mixed Phenotype Acute Leukemia+5 more Children's Oncology Group
Testing effectiveness (Phase 2)Active Not RecruitingNCT03399773What this trial is testingInfusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic SyndromesWho this might be right forAcute Biphenotypic LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia, BCR-ABL1 Positive+3 more Fred Hutchinson Cancer Center 31
Testing effectiveness (Phase 2)Ended earlyNCT01028716What this trial is testingDonor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic MalignanciesWho this might be right forAcute Biphenotypic LeukemiaAcute Erythroid Leukemia in RemissionAcute Leukemia in Remission+27 more Fred Hutchinson Cancer Center 46
Testing effectiveness (Phase 2)Looking for participantsNCT06928662What this trial is testingChemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of RelapseWho this might be right forAcute Myeloid LeukemiaAcute Undifferentiated LeukemiaMixed Phenotype Acute Leukemia+11 more Fred Hutchinson Cancer Center 36
Testing effectiveness (Phase 2)Looking for participantsNCT03670966What this trial is testing211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic SyndromeWho this might be right forAcute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia in Remission+9 more Fred Hutchinson Cancer Center 30
Testing effectiveness (Phase 2)Study completedNCT04827745What this trial is testingBlinatumomab for Treatment of R/R or MRD-positive CD19-Positive MPALWho this might be right forMixed Phenotype Acute Leukemia (MPAL)Measurable Residual Disease (MRD) University of Maryland, Baltimore 2