Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Refractory Brain Neoplasm”

254 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 254 results

Not applicableEnded earlyNCT01954576
What this trial is testing

NovoTTF Therapy in Treating Patients With Recurrent Glioblastoma Multiforme

Who this might be right for
GlioblastomaBrain Neoplasms
University of Florida 21
Early research (Phase 1)WithdrawnNCT00458744
What this trial is testing

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Children's Oncology Group
Testing effectiveness (Phase 2)Study completedNCT02654106
What this trial is testing

Stereotactic Radiotherapy Plus Temozolomide for Refractory Brain Metastases

Who this might be right for
Brain Metastases
Chinese Academy of Medical Sciences 65
Testing effectiveness (Phase 2)Ended earlyNCT01836549
What this trial is testing

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAstrocytoma, Grade II+6 more
Pediatric Brain Tumor Consortium 43
Testing effectiveness (Phase 2)Ended earlyNCT00014443
What this trial is testing

Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Rush University Medical Center 5
Early research (Phase 1)Study completedNCT01222780
What this trial is testing

To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer

Who this might be right for
SarcomaNeuroblastomaWilms Tumor+3 more
Acrotech Biopharma Inc. 22
Testing effectiveness (Phase 2)Looking for participantsNCT06510283
What this trial is testing

Efficacy and Safety of Taitacept in Treatment of Refractory or Recurrent Anti-NMDAR/anti-LGI1 Encephalitis

Who this might be right for
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Beijing Tongren Hospital 10
Testing effectiveness (Phase 2)Study completedNCT02596828
What this trial is testing

Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma

Who this might be right for
Pineoblastoma
University of Regensburg 4
Testing effectiveness (Phase 2)UnknownNCT02839954
What this trial is testing

CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor

Who this might be right for
Hepatocellular CarcinomaNon-small Cell Lung CancerPancreatic Carcinoma+4 more
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
Large-scale testing (Phase 3)Ended earlyNCT03149575
What this trial is testing

VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM

Who this might be right for
Glioblastoma MultiformeGlioblastomaGlioma+2 more
DelMar Pharmaceuticals, Inc. 2
Early research (Phase 1)Study completedNCT00019019
What this trial is testing

Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerKidney Cancer+6 more
National Institutes of Health Clinical Center (CC) 70
Large-scale testing (Phase 3)Study completedNCT00666211
What this trial is testing

Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Vanderbilt-Ingram Cancer Center 98
Early research (Phase 1)Active Not RecruitingNCT03389802
What this trial is testing

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Who this might be right for
Glioblastoma MultiformeHigh-grade Astrocytoma Not Otherwise Specified (NOS)CNS Primary Tumor, Not Otherwise Specified (NOS)+3 more
Pediatric Brain Tumor Consortium 32
Early research (Phase 1)Ended earlyNCT02255461
What this trial is testing

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Who this might be right for
Childhood Choroid Plexus TumorChildhood EpendymoblastomaChildhood Grade III Meningioma+16 more
Pediatric Brain Tumor Consortium 35
Early research (Phase 1)Study completedNCT00098761
What this trial is testing

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 42
Testing effectiveness (Phase 2)Study completedNCT00004078
What this trial is testing

Irinotecan in Treating Children With Refractory Solid Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+18 more
Children's Oncology Group 181
Large-scale testing (Phase 3)Ended earlyNCT00761280
What this trial is testing

Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma

Who this might be right for
Anaplastic AstrocytomaGlioblastoma
Isarna Therapeutics GmbH 27
Testing effectiveness (Phase 2)Ended earlyNCT01517776
What this trial is testing

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents

Who this might be right for
Gliomas
Martin-Luther-Universität Halle-Wittenberg 28
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Early research (Phase 1)Study completedNCT02564198
What this trial is testing

Ramucirumab (LY3009806) in Children With Refractory Solid Tumors

Who this might be right for
Pediatric Solid TumorRefractory TumorRecurrent Tumor+1 more
Eli Lilly and Company 29
Load More Results