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Results for “Refractory Brain Neoplasm”

255 trials

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Showing 20 of 255 results

Early research (Phase 1)Study completedNCT00001565
What this trial is testing

Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancy

Who this might be right for
Brain NeoplasmsNeuroblastoma
National Cancer Institute (NCI) 35
Early research (Phase 1)Study completedNCT01238237
What this trial is testing

Super-Selective Intraarterial Cerebral Infusion of Cetuximab (Erbitux) for Treatment of Relapsed/Refractory GBM and AA

Who this might be right for
Glioblastoma Multiforme (GBM)ANAPLASTIC ASTROCYTOMA (AOA)GBM+1 more
Northwell Health 15
Early research (Phase 1)Study completedNCT00006246
What this trial is testing

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorLeukemia+4 more
Pediatric Brain Tumor Consortium 28
Testing effectiveness (Phase 2)Looking for participantsNCT06208657
What this trial is testing

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

Who this might be right for
Childhood CancerChildhood Solid TumorChildhood Brain Tumor+2 more
Australian & New Zealand Children's Haematology/Oncology Group 90
Testing effectiveness (Phase 2)Study completedNCT04238819
What this trial is testing

Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Who this might be right for
Relapsed Solid TumorRefractory Solid Tumor
Eli Lilly and Company 47
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Not applicableEnded earlyNCT00726830
What this trial is testing

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
M.D. Anderson Cancer Center 1
Early research (Phase 1)Study completedNCT00946335
What this trial is testing

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+25 more
National Cancer Institute (NCI) 31
Testing effectiveness (Phase 2)Study completedNCT01462695
What this trial is testing

Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma

Who this might be right for
Childhood Cerebellar Anaplastic AstrocytomaChildhood Cerebral Anaplastic AstrocytomaChildhood Cerebral Astrocytoma+8 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Study completedNCT00025311
What this trial is testing

Topotecan in Treating Patients With Recurrent, Progressive, or Refractory Cancer That is Metastatic to the Lining Around the Brain

Who this might be right for
Brain and Central Nervous System Tumors
NYU Langone Health
Early research (Phase 1)Active Not RecruitingNCT03500991
What this trial is testing

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

Who this might be right for
Central Nervous System Tumor, PediatricGliomaEpendymoma+6 more
Seattle Children's Hospital 10
Early research (Phase 1)Ended earlyNCT00512460
What this trial is testing

RTA 744 Injection in Patients With Leptomeningeal Disease

Who this might be right for
Neoplastic MeningitisSolid TumorLymphoma+2 more
M.D. Anderson Cancer Center 7
Large-scale testing (Phase 3)Ended earlyNCT03149575
What this trial is testing

VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM

Who this might be right for
Glioblastoma MultiformeGlioblastomaGlioma+2 more
DelMar Pharmaceuticals, Inc. 2
Early research (Phase 1)Study completedNCT01076530
What this trial is testing

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System ChoriocarcinomaChildhood Central Nervous System Embryonal Tumor+31 more
National Cancer Institute (NCI) 27
Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Early research (Phase 1)Study completedNCT00015899
What this trial is testing

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 53
Early research (Phase 1)Study completedNCT00053963
What this trial is testing

FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia

Who this might be right for
Blastic Phase Chronic Myelogenous LeukemiaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Study completedNCT00503724
What this trial is testing

Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors

Who this might be right for
Brain and Central Nervous System TumorsNeuroblastoma
Pediatric Brain Tumor Consortium 32
Early research (Phase 1)Study completedNCT04430842
What this trial is testing

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Who this might be right for
AstrocytomaBrain CancerBrain Metastases+20 more
Quadriga Biosciences, Inc. 15
Early research (Phase 1)Looking for participantsNCT05857969
What this trial is testing

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

Who this might be right for
Recurrent Childhood Acute Myeloid LeukemiaRecurrent Childhood Acute Lymphoblastic LeukemiaRecurrent Childhood Large Cell Lymphoma+15 more
Florida International University 65
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