Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Refractory Brain Tumor”

254 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 254 results

Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Testing effectiveness (Phase 2)Study completedNCT00875433
What this trial is testing

Afatinib (BIBW 2992) QTcF Trial in Patients With Relapsed or Refractory Solid Tumours

Who this might be right for
Neoplasms
Boehringer Ingelheim 60
Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Testing effectiveness (Phase 2)Study completedNCT00004078
What this trial is testing

Irinotecan in Treating Children With Refractory Solid Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+18 more
Children's Oncology Group 181
Early research (Phase 1)Study completedNCT00929903
What this trial is testing

Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment

Who this might be right for
Childhood Central Nervous System ChoriocarcinomaChildhood Central Nervous System Embryonal TumorChildhood Central Nervous System Germ Cell Tumor+10 more
National Cancer Institute (NCI) 55
Early research (Phase 1)Study completedNCT00011414
What this trial is testing

Phase I Trial of Tariquidar (XR9576) in Combination With Doxorubicin, Vinorelbine, or Docetaxel in Pediatric Patients With Solid Tumors

Who this might be right for
Wilms' TumorSarcomaAdenaocortical Carcinoma+2 more
National Cancer Institute (NCI) 29
Early research (Phase 1)Looking for participantsNCT05521984
What this trial is testing

Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

Who this might be right for
Pediatric Brain TumorPediatric Solid Tumor
Washington University School of Medicine 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Testing effectiveness (Phase 2)Ended earlyNCT03690869
What this trial is testing

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Who this might be right for
Relapsed Solid TumorRefractory Solid TumorRelapsed Central Nervous System Tumor+3 more
Regeneron Pharmaceuticals 57
Very early researchLooking for participantsNCT06828341
What this trial is testing

A Single-arm, Open, Exploratory Clinical Study of Allogeneic CAR-T Cells in the Treatment of Relapsed/Refractory Brain Gliomas With Positive CD70 Expression

Who this might be right for
Gliomas
JIANG LONGWEI 3
Early research (Phase 1)Study completedNCT04023669
What this trial is testing

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

Who this might be right for
Brain TumorBrain Tumor, RecurrentBrain Tumor, Refractory+10 more
St. Jude Children's Research Hospital 21
Early research (Phase 1)UnknownNCT00360854
What this trial is testing

Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapsed Malignant Brain Tumors or Newly Diagnosed Brain Stem Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Children's Cancer and Leukaemia Group 48
Early research (Phase 1)Study completedNCT00101270
What this trial is testing

Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Diffuse Large Cell Lymphoma+26 more
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)WithdrawnNCT02425072
What this trial is testing

NovoTTF-100A Therapy for Refractory CNS Involved Small Cell Lung Cancer

Who this might be right for
Small Cell Lung CancerBrain Metastasis
John Villano
Testing effectiveness (Phase 2)Looking for participantsNCT01269853
What this trial is testing

Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

Who this might be right for
Glioblastoma MultiformeAnaplastic Astrocytoma
Northwell Health 54
Early research (Phase 1)Study completedNCT00001565
What this trial is testing

Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancy

Who this might be right for
Brain NeoplasmsNeuroblastoma
National Cancer Institute (NCI) 35
Large-scale testing (Phase 3)Ended earlyNCT03149575
What this trial is testing

VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM

Who this might be right for
Glioblastoma MultiformeGlioblastomaGlioma+2 more
DelMar Pharmaceuticals, Inc. 2
Not applicableUnknownNCT02015728
What this trial is testing

Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors

Who this might be right for
Recurrent Childhood Brain Tumor
Seattle Children's Hospital 20
Early research (Phase 1)Study completedNCT00363272
What this trial is testing

Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Study completedNCT00003457
What this trial is testing

Antineoplaston Therapy in Treating Patients With Brain Tumors

Who this might be right for
Refractory Brain Tumors
Burzynski Research Institute 40
Load More Results