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Results for “Refractory Central Nervous System Neoplasm”

384 trials

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Showing 20 of 384 results

Testing effectiveness (Phase 2)Study completedNCT02312622
What this trial is testing

Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer

Who this might be right for
Stage IV Non-small Cell Lung Cancer (NSCLC)Recurrent Non-small Cell Lung Cancer (NSCLC)Extensive-stage Small Cell Lung Cancer (SCLC)+3 more
Joel Neal 27
Testing effectiveness (Phase 2)Ended earlyNCT02420795
What this trial is testing

Akt/ERK Inhibitor ONC201 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Who this might be right for
Central Nervous System LymphomaGastric Mantle Cell LymphomaRecurrent Mantle Cell Lymphoma+4 more
M.D. Anderson Cancer Center 16
Testing effectiveness (Phase 2)Study completedNCT02116777
What this trial is testing

Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies

Who this might be right for
Adult Solid NeoplasmChildhood Solid NeoplasmRecurrent Childhood Central Nervous System Neoplasm+3 more
National Cancer Institute (NCI) 40
Early research (Phase 1)Study completedNCT04334863
What this trial is testing

WP1066 in Children With Refractory and Progressive or Recurrent Malignant Brain Tumors

Who this might be right for
Brain TumorMedulloblastomaBrain Metastases
Emory University 10
Early research (Phase 1)Study completedNCT00994071
What this trial is testing

A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors

Who this might be right for
MedulloblastomaPontine GliomaEpendymoma+2 more
National Cancer Institute (NCI) 9
Early research (Phase 1)Active Not RecruitingNCT06958939
What this trial is testing

The Safety and Efficacy of S103 in the Treatment of Refractory Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis, Generalized
Ting Chang, MD 10
Early research (Phase 1)Study completedNCT01875601
What this trial is testing

NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors

Who this might be right for
Solid TumorsBrain TumorsSarcoma+2 more
National Cancer Institute (NCI) 16
Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Testing effectiveness (Phase 2)Study completedNCT00070096
What this trial is testing

Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors

Who this might be right for
Brain and Central Nervous System TumorsExtragonadal Germ Cell TumorOvarian Cancer+1 more
Memorial Sloan Kettering Cancer Center 29
Early research (Phase 1)Study completedNCT00049023
What this trial is testing

Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsGastrointestinal Carcinoid TumorIslet Cell Tumor+4 more
O'Dorisio, M S 27
Large-scale testing (Phase 3)UnknownNCT00020865
What this trial is testing

Levofloxacin Compared With Cefepime in Treating Cancer Patients With Fever and Neutropenia

Who this might be right for
Fever, Sweats, and Hot FlashesInfectionLeukemia+3 more
Jonsson Comprehensive Cancer Center
Testing effectiveness (Phase 2)Study completedNCT02542514
What this trial is testing

Study of Ibrutinib in Patients With Relapsed or Refractory Primary Central Nervous Lymphoma or Intraocular Lymphoma

Who this might be right for
Primary Central Nervous LymphomaIntraocular Lymphoma
The Lymphoma Academic Research Organisation 52
Early research (Phase 1)UnknownNCT03631953
What this trial is testing

Combination of Alpelisib and Trametinib in Progressive Refractory Meningiomas

Who this might be right for
Meningioma
Assistance Publique Hopitaux De Marseille 25
Large-scale testing (Phase 3)Study completedNCT03759366
What this trial is testing

Open-Label Study of Eculizumab in Pediatric Participants With Refractory Generalized Myasthenia Gravis (gMG)

Who this might be right for
Myasthenia GravisMyasthenia Gravis, Juvenile FormMyasthenia Gravis, Generalized
Alexion Pharmaceuticals, Inc. 12
Early research (Phase 1)Looking for participantsNCT04510051
What this trial is testing

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

Who this might be right for
Malignant Brain NeoplasmRecurrent Malignant Brain NeoplasmRefractory Malignant Brain Neoplasm
City of Hope Medical Center 18
Early research (Phase 1)Study completedNCT01722305
What this trial is testing

Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma or Newly Diagnosed or Relapsed or Refractory Intraocular Lymphoma

Who this might be right for
B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt LymphomaCentral Nervous System LymphomaIntraocular Lymphoma+3 more
Mayo Clinic 29
Not applicableStudy completedNCT00376922
What this trial is testing

Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other Diseases

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+7 more
Wake Forest University Health Sciences 65
Early research (Phase 1)Ended earlyNCT00527410
What this trial is testing

A Safety Study of RTA 744 in Recurrent, Progressive or Refractory Neoplastic Meningitis

Who this might be right for
Leptomeningeal Carcinomatosis
Biogen 9
Testing effectiveness (Phase 2)Looking for participantsNCT04186520
What this trial is testing

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

Who this might be right for
Non Hodgkin Lymphoma (NHL)Mantle Cell Lymphoma (MCL)Chronic Lymphocytic Leukemia (CLL)+5 more
Medical College of Wisconsin 100
Early research (Phase 1)Study completedNCT00003597
What this trial is testing

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Who this might be right for
Cancer
Children's Oncology Group 16
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