Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Refractory Central Nervous System Tumor”

374 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 374 results

Early research (Phase 1)Study completedNCT00001565
What this trial is testing

Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancy

Who this might be right for
Brain NeoplasmsNeuroblastoma
National Cancer Institute (NCI) 35
Early research (Phase 1)Study completedNCT01238237
What this trial is testing

Super-Selective Intraarterial Cerebral Infusion of Cetuximab (Erbitux) for Treatment of Relapsed/Refractory GBM and AA

Who this might be right for
Glioblastoma Multiforme (GBM)ANAPLASTIC ASTROCYTOMA (AOA)GBM+1 more
Northwell Health 15
Early research (Phase 1)Study completedNCT00006246
What this trial is testing

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorLeukemia+4 more
Pediatric Brain Tumor Consortium 28
Testing effectiveness (Phase 2)Looking for participantsNCT06208657
What this trial is testing

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

Who this might be right for
Childhood CancerChildhood Solid TumorChildhood Brain Tumor+2 more
Australian & New Zealand Children's Haematology/Oncology Group 90
Testing effectiveness (Phase 2)Study completedNCT04238819
What this trial is testing

Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Who this might be right for
Relapsed Solid TumorRefractory Solid Tumor
Eli Lilly and Company 47
Not applicableStudy completedNCT05537675
What this trial is testing

Semi-automated Segmentation Methods of SSTR PET for Dosimetry Prediction

Who this might be right for
Refractory Meningioma
Central Hospital, Nancy, France 20
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Not applicableEnded earlyNCT00726830
What this trial is testing

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
M.D. Anderson Cancer Center 1
Early research (Phase 1)Study completedNCT00049712
What this trial is testing

Monoclonal Antibody Therapy in Treating Patients With Refractory Advanced Solid Tumors or Lymphoma

Who this might be right for
LymphomaSmall Intestine CancerUnspecified Adult Solid Tumor, Protocol Specific
University of Wisconsin, Madison
Early research (Phase 1)Study completedNCT00946335
What this trial is testing

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+25 more
National Cancer Institute (NCI) 31
Early research (Phase 1)Ended earlyNCT00004058
What this trial is testing

12-O-Tetradecanoylphorbol-13-acetate in Treating Patients With Hematologic Cancer or Bone Marrow Disorder

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+4 more
University of Medicine and Dentistry of New Jersey
Early research (Phase 1)Study completedNCT00025311
What this trial is testing

Topotecan in Treating Patients With Recurrent, Progressive, or Refractory Cancer That is Metastatic to the Lining Around the Brain

Who this might be right for
Brain and Central Nervous System Tumors
NYU Langone Health
Early research (Phase 1)Active Not RecruitingNCT03500991
What this trial is testing

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

Who this might be right for
Central Nervous System Tumor, PediatricGliomaEpendymoma+6 more
Seattle Children's Hospital 10
Early research (Phase 1)Study completedNCT01231919
What this trial is testing

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Leukemias of Ambiguous LineageAcute Myeloid Leukemia/Transient Myeloproliferative Disorder+48 more
National Cancer Institute (NCI) 45
Early research (Phase 1)Study completedNCT01460134
What this trial is testing

CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic Cancers

Who this might be right for
CD27 Expressing B-cell Malignancies for Example Hodgkin's LymphomaChronic Lymphocytic LeukemiaMantle Cell Lymphoma+7 more
Celldex Therapeutics 90
Early research (Phase 1)Ended earlyNCT00512460
What this trial is testing

RTA 744 Injection in Patients With Leptomeningeal Disease

Who this might be right for
Neoplastic MeningitisSolid TumorLymphoma+2 more
M.D. Anderson Cancer Center 7
Large-scale testing (Phase 3)Ended earlyNCT03149575
What this trial is testing

VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM

Who this might be right for
Glioblastoma MultiformeGlioblastomaGlioma+2 more
DelMar Pharmaceuticals, Inc. 2
Early research (Phase 1)Study completedNCT01076530
What this trial is testing

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System ChoriocarcinomaChildhood Central Nervous System Embryonal Tumor+31 more
National Cancer Institute (NCI) 27
Early research (Phase 1)Study completedNCT00045500
What this trial is testing

UCN-01 and Prednisone in Treating Patients With Solid Tumors or Lymphoma

Who this might be right for
LymphomaUnspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Load More Results