Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Refractory Central Nervous System Tumor”

377 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 377 results

Early research (Phase 1)WithdrawnNCT01130623
What this trial is testing

A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors

Who this might be right for
SarcomaNeuroblastomaWilms Tumor+2 more
National Cancer Institute (NCI)
Not applicableEnded earlyNCT01954576
What this trial is testing

NovoTTF Therapy in Treating Patients With Recurrent Glioblastoma Multiforme

Who this might be right for
GlioblastomaBrain Neoplasms
University of Florida 21
Testing effectiveness (Phase 2)Looking for participantsNCT05681195
What this trial is testing

Zanubrutinib With Pemetrexed to Treat Relapsed/Refractory Primary and Secondary Central Nervous System (CNS) Lymphomas

Who this might be right for
Primary Central Nervous System LymphomaSecondary Central Nervous System LymphomaRelapsed Cancer+1 more
Baptist Health South Florida 15
Testing effectiveness (Phase 2)Ended earlyNCT02420795
What this trial is testing

Akt/ERK Inhibitor ONC201 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Who this might be right for
Central Nervous System LymphomaGastric Mantle Cell LymphomaRecurrent Mantle Cell Lymphoma+4 more
M.D. Anderson Cancer Center 16
Early research (Phase 1)Looking for participantsNCT05131022
What this trial is testing

NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)Diffuse Large B Cell Lymphoma (DLBCL)+6 more
Nurix Therapeutics, Inc. 572
Testing effectiveness (Phase 2)Ended earlyNCT00727194
What this trial is testing

Safety and Efficacy Study of Eculizumab in Patients With Refractory Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis
Alexion Pharmaceuticals, Inc. 14
Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Testing effectiveness (Phase 2)Active Not RecruitingNCT02867592
What this trial is testing

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Who this might be right for
Adrenal Cortical CarcinomaAlveolar Soft Part SarcomaCentral Nervous System Neoplasm+41 more
National Cancer Institute (NCI) 109
Not applicableUnknownNCT05108064
What this trial is testing

Radiomic and Pathomic Study of Pituitary Adenoma Using Machine Learning

Who this might be right for
Pituitary Neoplasms
Huashan Hospital 1,000
Early research (Phase 1)Looking for participantsNCT04807881
What this trial is testing

Phase Ib Clinical Study of Keynatinib

Who this might be right for
Lymphoma, B-Cell
Medolution Ltd. 75
Early research (Phase 1)Study completedNCT00005021
What this trial is testing

Combination Chemotherapy With or Without Biological Therapy in Treating Patients With Refractory Solid Tumor or Lymphoma

Who this might be right for
LymphomaSmall Intestine CancerUnspecified Adult Solid Tumor, Protocol Specific
Fox Chase Cancer Center 17
Early research (Phase 1)Study completedNCT00994071
What this trial is testing

A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors

Who this might be right for
MedulloblastomaPontine GliomaEpendymoma+2 more
National Cancer Institute (NCI) 9
Early research (Phase 1)Study completedNCT01588015
What this trial is testing

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+123 more
City of Hope Medical Center 36
Early research (Phase 1)Study completedNCT01259479
What this trial is testing

Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors

Who this might be right for
Solid TumorsBrain TumorsBrain Metastases
National Cancer Institute (NCI) 9
Early research (Phase 1)Study completedNCT00063973
What this trial is testing

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+23 more
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Study completedNCT00268359
What this trial is testing

Bevacizumab and Irinotecan in Treating Patients With Recurrent or Refractory Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
Duke University 68
Testing effectiveness (Phase 2)Study completedNCT00004688
What this trial is testing

Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms

Who this might be right for
Anaplastic AstrocytomaAnaplastic OligodendrogliomaMixed Gliomas+2 more
Emory University 35
Large-scale testing (Phase 3)Ended earlyNCT00761280
What this trial is testing

Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma

Who this might be right for
Anaplastic AstrocytomaGlioblastoma
Isarna Therapeutics GmbH 27
Early research (Phase 1)Active Not RecruitingNCT03500991
What this trial is testing

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

Who this might be right for
Central Nervous System Tumor, PediatricGliomaEpendymoma+6 more
Seattle Children's Hospital 10
Testing effectiveness (Phase 2)UnknownNCT05816746
What this trial is testing

Decitabine and Anti-PD-1 in R/R DLBCL

Who this might be right for
Diffuse Large B Cell LymphomaRelapse/RecurrenceExtranodal Extension+1 more
Chinese PLA General Hospital 20
Load More Results