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Results for “Refractory Cholangiocarcinoma”

31 trials

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Showing 20 of 31 results

Early research (Phase 1)Study completedNCT04676633
What this trial is testing

Safety, Tolerability, PK, Anti-Tumor Activity of STP705 in Subjects With Advanced/Metastatic or Surgically Unresectable Solid Tumors Who Are Refractory to Standard Therapy

Who this might be right for
Hepatocellular CarcinomaLiver MetastasesCholangiocarcinoma
Sirnaomics 5
Testing effectiveness (Phase 2)Study completedNCT02042443
What this trial is testing

Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery

Who this might be right for
Adult CholangiocarcinomaAdvanced Adult Hepatocellular CarcinomaBCLC Stage C Adult Hepatocellular Carcinoma+16 more
National Cancer Institute (NCI) 53
Early research (Phase 1)Study completedNCT04430842
What this trial is testing

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Who this might be right for
AstrocytomaBrain CancerBrain Metastases+20 more
Quadriga Biosciences, Inc. 15
Testing effectiveness (Phase 2)Study completedNCT00019474
What this trial is testing

Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer

Who this might be right for
Extrahepatic Bile Duct CancerGastric CancerGastrointestinal Carcinoid Tumor+3 more
Montefiore Medical Center 60
Early research (Phase 1)Study completedNCT00019513
What this trial is testing

Combination Chemotherapy in Treating Patients With Recurrent, Refractory, or Metastatic Solid Tumors or Lymphomas

Who this might be right for
Colorectal CancerEsophageal CancerExtrahepatic Bile Duct Cancer+7 more
National Institutes of Health Clinical Center (CC) 108
Testing effectiveness (Phase 2)WithdrawnNCT03999658
What this trial is testing

STI-3031 (an Anti-PD-L1 Antibody) in Patients With Selected Relapsed/Refractory Malignancies

Who this might be right for
Peripheral T Cell LymphomaDiffuse Large B Cell LymphomaBiliary Tract Cancer+1 more
Sorrento Therapeutics, Inc.
Early research (Phase 1)Study completedNCT00073944
What this trial is testing

BCX-1777 in Treating Patients With Refractory Cancer

Who this might be right for
Cancer
BioCryst Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT04072445
What this trial is testing

Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

Who this might be right for
Advanced Bile Duct CarcinomaAdvanced Gallbladder CarcinomaRefractory Bile Duct Carcinoma+15 more
Mayo Clinic 28
Early research (Phase 1)Looking for participantsNCT06302621
What this trial is testing

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorMetastatic Solid Tumor+1 more
Massachusetts General Hospital 70
Large-scale testing (Phase 3)Study completedNCT00538850
What this trial is testing

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Who this might be right for
Cancer
INSYS Therapeutics Inc 130
Testing effectiveness (Phase 2)Study completedNCT04656249
What this trial is testing

Lenvatinib in Patients With Previously Treated Advanced Biliary Tract Cancer

Who this might be right for
CholangiocarcinomaBiliary Tract CancerTargeted Therapy
Peking Union Medical College Hospital 46
Testing effectiveness (Phase 2)Study completedNCT01425879
What this trial is testing

MK2206 in Treating Patients With Advanced Refractory Biliary Cancer That Cannot Be Removed by Surgery

Who this might be right for
Advanced Adult Hepatocellular CarcinomaLocalized Non-Resectable Adult Liver CarcinomaRecurrent Adult Liver Carcinoma+5 more
National Cancer Institute (NCI) 8
Early research (Phase 1)Study completedNCT00949949
What this trial is testing

Everolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable Solid Tumors Refractory to Standard Therapy

Who this might be right for
Cholangiocarcinoma of the GallbladderLocalized Gallbladder CancerUnresectable Gallbladder Cancer+1 more
Mayo Clinic 38
Early research (Phase 1)Study completedNCT00003439
What this trial is testing

Interleukin-12 in Treating Patients With Refractory Advanced-Stage Ovarian Cancer or Abdominal Cancer

Who this might be right for
Cancer
National Cancer Institute (NCI) 36
Early research (Phase 1)Ended earlyNCT06420349
What this trial is testing

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Who this might be right for
Advanced CholangiocarcinomaMetastatic CholangiocarcinomaRefractory Cholangiocarcinoma+4 more
Mayo Clinic 7
Testing effectiveness (Phase 2)Study completedNCT01290536
What this trial is testing

Yttrium-90 Radioembolization Using Glass Microspheres (TheraSphere) for Patients With Liver Metastases

Who this might be right for
Colorectal NeoplasmsNeuroendocrine TumorsCholangiocarcinoma+2 more
Nicholas Fidelman, MD 42
Testing effectiveness (Phase 2)Study completedNCT03602079
What this trial is testing

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

Who this might be right for
HER2-positive Breast CancerHER2 Gene MutationHER-2 Gene Amplification+41 more
Klus Pharma Inc. 49
Early research (Phase 1)Ended earlyNCT02908451
What this trial is testing

AbGn-107 in Patients With Gastric, Colorectal, Pancreatic or Biliary Cancer

Who this might be right for
Gastric CancerColorectal CancerPancreatic Cancer+1 more
AbGenomics B.V Taiwan Branch 39
Testing effectiveness (Phase 2)Ended earlyNCT04566133
What this trial is testing

Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).

Who this might be right for
Bile Duct CancerBiliary CancerBiliary Tract Neoplasms+1 more
National Cancer Institute (NCI) 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT03878095
What this trial is testing

Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors

Who this might be right for
Malignant Solid NeoplasmRefractory CholangiocarcinomaRefractory Malignant Solid Neoplasm
National Cancer Institute (NCI) 24
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