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Results for “Refractory Colorectal Carcinoma”

331 trials

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Showing 20 of 331 results

Testing effectiveness (Phase 2)Ended earlyNCT04786600
What this trial is testing

A Phase II Randomized Therapeutic Optimization Trial for Subjects With Refractory Metastatic Colorectal Cancer Using ctDNA: Rapid 1 Trial

Who this might be right for
Metastatic Colorectal Cancer
University of Florida 6
Testing effectiveness (Phase 2)Ended earlyNCT01109615
What this trial is testing

Pemetrexed and Gemcitabine for Treatment Resistant Patients With Metastatic Colorectal Cancer and KRAS Mutations

Who this might be right for
Metastatic Colorectal Cancer
Vejle Hospital 40
Testing effectiveness (Phase 2)Study completedNCT02260440
What this trial is testing

Pembrolizumab (MK-3475) in Combination With Azacitidine in Subjects With Chemo-refractory Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Anuradha Krishnamurthy 31
Not applicableActive Not RecruitingNCT05487248
What this trial is testing

On-treatment ctDNA Changes in Chemo-refractory Colorectal Cancer Patients

Who this might be right for
Unresectable Locally Advanced Colorectal CancerMetastatic Colorectal CancerCandidate for Third-line or Subsequent Lines of Therapy
Jules Bordet Institute 103
Testing effectiveness (Phase 2)Ended earlyNCT05551117
What this trial is testing

Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors

Who this might be right for
Castration-Resistant Prostatic CancerAndrogen-Independent Prostatic CancerAndrogen-Insensitive Prostatic Cancer+14 more
MacroGenics 192
Early research (Phase 1)Study completedNCT02835833
What this trial is testing

Study of Nintedanib Plus Bevacizumab in Advanced Solid Tumors

Who this might be right for
Renal Cell CarcinomaColorectal AdenocarcinomaNon-squamous Non-small Cell Lung Cancer+2 more
University of Alabama at Birmingham 21
Early research (Phase 1)Ended earlyNCT07121829
What this trial is testing

Tovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid Tumors

Who this might be right for
MelanomaSolid TumorPilocytic Astrocytoma+7 more
Day One Biopharmaceuticals, Inc. 44
Testing effectiveness (Phase 2)UnknownNCT02839954
What this trial is testing

CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor

Who this might be right for
Hepatocellular CarcinomaNon-small Cell Lung CancerPancreatic Carcinoma+4 more
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
Testing effectiveness (Phase 2)Study completedNCT00842257
What this trial is testing

Panitumumab in Cetuximab Refractory KRAS Wild-Type Colorectal Cancer

Who this might be right for
Colorectal Cancer
Massachusetts General Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT07012954
What this trial is testing

CtDNA-Guided Cetuximab or Bevacizumab Plus Trifluridine/Tipiracil in RAS/BRAF Wild-Type mCRC

Who this might be right for
Colorectal Cancer Metastatic
Sun Yat-sen University 64
Early research (Phase 1)UnknownNCT04107142
What this trial is testing

Haplo / Allogeneic NKG2DL-targeting Chimeric Antigen Receptor-grafted γδ T Cells for Relapsed or Refractory Solid Tumour

Who this might be right for
Colorectal CancerTriple Negative Breast CancerSarcoma+3 more
CytoMed Therapeutics Pte Ltd 10
Early research (Phase 1)Active Not RecruitingNCT02595931
What this trial is testing

M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Metastatic Colorectal CarcinomaMetastatic Lung Small Cell CarcinomaMetastatic Malignant Solid Neoplasm+15 more
National Cancer Institute (NCI) 66
Testing effectiveness (Phase 2)Study completedNCT03258398
What this trial is testing

Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal Cancer

Who this might be right for
Microsatellite Stable Relapsed or Refractory Colorectal Cancer
Effector Therapeutics 56
Early research (Phase 1)Study completedNCT00940758
What this trial is testing

Phase I and Pharmacokinetic Study of Biweekly PEP02 in mCRC Refractory to 1st-line Oxaliplatin Base Therapy

Who this might be right for
Metastatic Colorectal Cancer
PharmaEngine 18
Testing effectiveness (Phase 2)UnknownNCT00081536
What this trial is testing

Aroplatin and Capecitabine in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies

Who this might be right for
Colorectal Neoplasms
Aronex Pharmaceuticals 105
Testing effectiveness (Phase 2)Looking for participantsNCT06699836
What this trial is testing

Leronlimab in Combination With TAS-102 + Bevacizumab in Previously Treated Participants With mCRC

Who this might be right for
Metastatic Colorectal Cancer (mCRC)
CytoDyn, Inc. 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT03087071
What this trial is testing

Panitumumab With or Without Trametinib in Treating Patients With Stage IV Colorectal Cancer

Who this might be right for
EGFR NP_005219.2:p.S492RKRAS Gene MutationMAP2K1 Gene Mutation+5 more
M.D. Anderson Cancer Center 59
Testing effectiveness (Phase 2)Study completedNCT00051987
What this trial is testing

Phase 2b Study of VELCADE Alone and VELCADE Plus Irinotecan in Patients With Relapsed or Refractory Colorectal Carcinoma

Who this might be right for
Colorectal Carcinoma
Millennium Pharmaceuticals, Inc. 175
Testing effectiveness (Phase 2)Looking for participantsNCT06427005
What this trial is testing

Fruquintinib Plus S-1 and Raltitrexed (RSF) for MCRC

Who this might be right for
FruquintinibS-1Raltitrexed
Meng Qiu 66
Testing effectiveness (Phase 2)Ended earlyNCT00126451
What this trial is testing

A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Relapsed or Refractory Breast, Colorectal and Non-Small Cell Lung Cancer (0683-011)(TERMINATED)

Who this might be right for
Breast CancerColorectal CancerNon-small-cell Lung Carcinoma
Merck Sharp & Dohme LLC 16
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