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Results for “Refractory DIPG”

16 trials

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Showing 16 of 16 results

Testing effectiveness (Phase 2)Ended earlyNCT01774253
What this trial is testing

Erivedge (Vismodegib) in the Treatment of Pediatric Patients With Refractory Pontine Glioma

Who this might be right for
Pontine Glioma
Giselle Sholler 9
Early research (Phase 1)Not Yet RecruitingNCT07331064
What this trial is testing

Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid Tumor

Who this might be right for
High Grade GliomasAtypical Teratoid Rhabdoid Tumors (ATRT)Diffuse Midline Glioma+2 more
Sarah Rumler 15
Testing effectiveness (Phase 2)Looking for participantsNCT05956821
What this trial is testing

Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

Who this might be right for
Glioblastoma MultiformeAnaplastic AstrocytomaFibrillary Astrocytomas+5 more
University of Miami 20
Early research (Phase 1)Looking for participantsNCT04185038
What this trial is testing

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Who this might be right for
Central Nervous System TumorDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma+8 more
Seattle Children's Hospital 90
Testing effectiveness (Phase 2)Active Not RecruitingNCT06521567
What this trial is testing

Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Who this might be right for
MelanomaHodgkin LymphomaHigh and Low Grade Glioma+9 more
GlaxoSmithKline 83
Early research (Phase 1)Active Not RecruitingNCT05768880
What this trial is testing

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline GliomaRecurrent CNS Tumor, Adult+2 more
Seattle Children's Hospital 72
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Testing effectiveness (Phase 2)Study completedNCT02750891
What this trial is testing

DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas

Who this might be right for
GlioblastomaDiffuse Intrinsic Pontine Glioma
Sumitomo Pharma Co., Ltd. 18
Testing effectiveness (Phase 2)Looking for participantsNCT06465199
What this trial is testing

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

Who this might be right for
Atypical Teratoid/Rhabdoid TumorEmbryonal Tumor With Multilayered RosettesEwing Sarcoma+4 more
Milton S. Hershey Medical Center 265
Early research (Phase 1)Active Not RecruitingNCT03478462
What this trial is testing

Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas

Who this might be right for
Pediatric Solid TumorPediatric LymphomaPediatric Brain Tumor+5 more
Cellectar Biosciences, Inc. 30
Testing effectiveness (Phase 2)Looking for participantsNCT06838676
What this trial is testing

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Who this might be right for
Diffuse Intrinsic Pontine Gliomas (DIPG)Progressive DIPGRefractory DIPG+2 more
Nationwide Children's Hospital 60
Testing effectiveness (Phase 2)Looking for participantsNCT06607692
What this trial is testing

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

Who this might be right for
Solid Tumor CancerMedulloblastomaHigh Risk Neuroblastoma+19 more
Fundación de investigación HM 25
Early research (Phase 1)Active Not RecruitingNCT02359565
What this trial is testing

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeLynch SyndromeMalignant Glioma+8 more
National Cancer Institute (NCI) 71
Testing effectiveness (Phase 2)Ended earlyNCT04730349
What this trial is testing

Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer

Who this might be right for
EpendymomaEwing SarcomaHigh-grade Glioma+7 more
Bristol-Myers Squibb 15
Not applicableStudy completedNCT03538587
What this trial is testing

Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers

Who this might be right for
GlioblastomasSarcomaAstrocytoma+2 more
National Cancer Institute (NCI) 10
Early research (Phase 1)Study completedNCT03389802
What this trial is testing

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Who this might be right for
Glioblastoma MultiformeHigh-grade Astrocytoma Not Otherwise Specified (NOS)CNS Primary Tumor, Not Otherwise Specified (NOS)+3 more
Pediatric Brain Tumor Consortium 32