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Results for “Refractory Glioblastoma”

125 trials

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Showing 20 of 125 results

Not applicableEnded earlyNCT01954576
What this trial is testing

NovoTTF Therapy in Treating Patients With Recurrent Glioblastoma Multiforme

Who this might be right for
GlioblastomaBrain Neoplasms
University of Florida 21
Testing effectiveness (Phase 2)Looking for participantsNCT07410494
What this trial is testing

Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
CancerBreast CancerNon-Small Cell Lung Cancer (NSCLC)+10 more
Essen Biotech 85
Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Early research (Phase 1)Study completedNCT00063973
What this trial is testing

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+23 more
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Study completedNCT00268359
What this trial is testing

Bevacizumab and Irinotecan in Treating Patients With Recurrent or Refractory Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
Duke University 68
Testing effectiveness (Phase 2)Study completedNCT00004688
What this trial is testing

Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms

Who this might be right for
Anaplastic AstrocytomaAnaplastic OligodendrogliomaMixed Gliomas+2 more
Emory University 35
Testing effectiveness (Phase 2)Study completedNCT03243851
What this trial is testing

Study on Low Dose Temozolomide Plus Metformin or Placebo in Patient With Recurrent or Refractory Glioblastoma

Who this might be right for
Glioblastoma
Yong-Kil Hong 81
Large-scale testing (Phase 3)Ended earlyNCT00761280
What this trial is testing

Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma

Who this might be right for
Anaplastic AstrocytomaGlioblastoma
Isarna Therapeutics GmbH 27
Early research (Phase 1)Study completedNCT00138216
What this trial is testing

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsUnspecified Childhood Solid Tumor, Protocol Specific
Children's Oncology Group 42
Testing effectiveness (Phase 2)Ended earlyNCT00788125
What this trial is testing

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
City of Hope Medical Center 7
Early research (Phase 1)Study completedNCT00526812
What this trial is testing

A Safety Study of RTA 744 in Patients With Recurrent High-Grade Gliomas

Who this might be right for
Glioma
Biogen 54
Testing effectiveness (Phase 2)Study completedNCT03660761
What this trial is testing

Apatinib in Recurrent or Refractory Intracranial Central Nervous System Malignant Tumors

Who this might be right for
Efficacy and Safety
Rongjie Tao 25
Testing effectiveness (Phase 2)Study completedNCT02684058
What this trial is testing

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Who this might be right for
Diffuse AstrocytomaAnaplastic AstrocytomaAstrocytoma+19 more
Novartis Pharmaceuticals 151
Early research (Phase 1)Study completedNCT01082926
What this trial is testing

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Meningioma+11 more
City of Hope Medical Center 6
Early research (Phase 1)Study completedNCT01295632
What this trial is testing

Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049)

Who this might be right for
Advanced Cancer
Merck Sharp & Dohme LLC 65
Early research (Phase 1)Ended earlyNCT00990496
What this trial is testing

A Study Using Allogenic-Cytomegalovirus (CMV) Specific Cells for Glioblastoma Multiforme (GBM)

Who this might be right for
Glioblastoma Multiforme
Milton S. Hershey Medical Center 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05540275
What this trial is testing

Tislelizumab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for Bevacizumab Refractory Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma
Henan Provincial People's Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT01269853
What this trial is testing

Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

Who this might be right for
Glioblastoma MultiformeAnaplastic Astrocytoma
Northwell Health 54
Early research (Phase 1)Study completedNCT00544284
What this trial is testing

Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLymphomaMetastatic Cancer+1 more
City of Hope Medical Center 25
Early research (Phase 1)Study completedNCT00946335
What this trial is testing

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+25 more
National Cancer Institute (NCI) 31
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