Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Refractory Glioma”

271 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 271 results

Not applicableEnded earlyNCT01954576
What this trial is testing

NovoTTF Therapy in Treating Patients With Recurrent Glioblastoma Multiforme

Who this might be right for
GlioblastomaBrain Neoplasms
University of Florida 21
Early research (Phase 1)WithdrawnNCT00458744
What this trial is testing

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Children's Oncology Group
Testing effectiveness (Phase 2)Study completedNCT01239316
What this trial is testing

Vismodegib in Treating Younger Patients With Recurrent or Refractory Medulloblastoma

Who this might be right for
Recurrent Childhood Medulloblastoma
National Cancer Institute (NCI) 12
Not applicableWithdrawnNCT03636958
What this trial is testing

Efficacy and Safety of Perampanel in Combination in Glioma-refractory Epilepsy

Who this might be right for
Refractory Epilepsy
Assistance Publique Hopitaux De Marseille
Testing effectiveness (Phase 2)Ended earlyNCT01836549
What this trial is testing

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAstrocytoma, Grade II+6 more
Pediatric Brain Tumor Consortium 43
Testing effectiveness (Phase 2)Ended earlyNCT00014443
What this trial is testing

Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Rush University Medical Center 5
Early research (Phase 1)Temporarily pausedNCT06355908
What this trial is testing

IL13Rα2 CAR-T for Patients With r/r Glioma

Who this might be right for
Glioma
Yang Zhang 30
Early research (Phase 1)Ended earlyNCT07121829
What this trial is testing

Tovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid Tumors

Who this might be right for
MelanomaSolid TumorPilocytic Astrocytoma+7 more
Day One Biopharmaceuticals, Inc. 44
Early research (Phase 1)Ended earlyNCT05429502
What this trial is testing

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Who this might be right for
Neuroblastoma
Novartis Pharmaceuticals 12
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05540275
What this trial is testing

Tislelizumab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for Bevacizumab Refractory Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma
Henan Provincial People's Hospital 30
Testing effectiveness (Phase 2)UnknownNCT02839954
What this trial is testing

CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor

Who this might be right for
Hepatocellular CarcinomaNon-small Cell Lung CancerPancreatic Carcinoma+4 more
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
Large-scale testing (Phase 3)Ended earlyNCT03149575
What this trial is testing

VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM

Who this might be right for
Glioblastoma MultiformeGlioblastomaGlioma+2 more
DelMar Pharmaceuticals, Inc. 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)Study completedNCT02626364
What this trial is testing

Study of Crenolanib in Recurrent/Refractory Glioblastoma With PDGFRA Gene Amplification

Who this might be right for
Recurrent/Refractory Glioblastoma
Arog Pharmaceuticals, Inc. 11
Not applicableLooking for participantsNCT07242963
What this trial is testing

Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study

Who this might be right for
Medulloblastoma RecurrentMedulloblastoma, Childhood, RecurrentMedulloblastoma, SHH-activated and TP53 Mutant+1 more
Mohammad H. Abu Arja 300
Early research (Phase 1)Study completedNCT00019019
What this trial is testing

Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerKidney Cancer+6 more
National Institutes of Health Clinical Center (CC) 70
Early research (Phase 1)Active Not RecruitingNCT03389802
What this trial is testing

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Who this might be right for
Glioblastoma MultiformeHigh-grade Astrocytoma Not Otherwise Specified (NOS)CNS Primary Tumor, Not Otherwise Specified (NOS)+3 more
Pediatric Brain Tumor Consortium 32
Early research (Phase 1)Ended earlyNCT02255461
What this trial is testing

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Who this might be right for
Childhood Choroid Plexus TumorChildhood EpendymoblastomaChildhood Grade III Meningioma+16 more
Pediatric Brain Tumor Consortium 35
Testing effectiveness (Phase 2)Study completedNCT04773782
What this trial is testing

Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling

Who this might be right for
Solid Tumor, Unspecified, ChildRelapsed Solid NeoplasmCNS Tumor
Blueprint Medicines Corporation 29
Early research (Phase 1)Study completedNCT00098761
What this trial is testing

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 42
Load More Results