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Results for “Refractory Head and Neck Squamous Cell Carcinoma”

96 trials

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Showing 20 of 96 results

Testing effectiveness (Phase 2)Study completedNCT02335918
What this trial is testing

A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck (SCCHN)Ovarian Carcinoma-Enrollment CompletedColorectal Cancer (CRC)-Enrollment Completed+2 more
Celldex Therapeutics 175
Large-scale testing (Phase 3)Not Yet RecruitingNCT07653451
What this trial is testing

Precision Medicine for Immunotherapy-Resistant Advanced Esophageal Cancer

Who this might be right for
Esophageal Squamous Cell Carcinoma
Peking University Cancer Hospital & Institute 90
Testing effectiveness (Phase 2)Looking for participantsNCT07189871
What this trial is testing

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

Who this might be right for
Castration-Resistant Prostate Cancer (CRPC)Colorectal CancerNSCLC (Non-small Cell Lung Cancer)+7 more
Radiopharm Theranostics, Ltd 61
Early research (Phase 1)Looking for participantsNCT07106827
What this trial is testing

GV20-0251 in Advanced or Refractory Solid Tumors

Who this might be right for
HCC - Hepatocellular CarcinomaCholangiocarcinomaMelanoma+5 more
West China Hospital 10
Early research (Phase 1)Looking for participantsNCT06999187
What this trial is testing

DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

Who this might be right for
Triple Negative Breast CancerHER2-negative Breast CancerNon Small Cell Lung Cancer+9 more
Dren Bio 96
Early research (Phase 1)Looking for participantsNCT07227168
What this trial is testing

STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

Who this might be right for
Head and Neck Squamous Cell Carcinoma HNSCCNon-Small Cell Lung Cancer NSCLCEsophageal Cancer+6 more
Sutro Biopharma, Inc. 200
Early research (Phase 1)Study completedNCT02475213
What this trial is testing

Safety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory Cancer

Who this might be right for
MelanomaHead and Neck CancerNon Small Cell Lung Cancer+1 more
MacroGenics 146
Early research (Phase 1)Study completedNCT02145637
What this trial is testing

Phase I Study of the Combination of Afatinib and Ruxolitinib in Patients With Treatment-refractory Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
NSCLC
Yonsei University 30
Not applicableEnded earlyNCT00904514
What this trial is testing

Study of Previously Collected and Stored Tissue Samples From Patients Previously Enrolled in a Completed National Cancer Institute Clinical Trial

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 241
Early research (Phase 1)Study completedNCT00049296
What this trial is testing

Thalidomide and Docetaxel in Treating Patients With Advanced Cancer

Who this might be right for
Cancer
Case Comprehensive Cancer Center 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT03474497
What this trial is testing

UCDCC#272: IL-2, Radiotherapy, and Pembrolizumab in Patients Refractory to Checkpoint Blockade

Who this might be right for
Non Small Cell Lung CancerMetastatic MelanomaMetastatic Renal Cell Carcinoma+1 more
Megan Daly, MD 18
Testing effectiveness (Phase 2)Ended earlyNCT05551117
What this trial is testing

Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors

Who this might be right for
Castration-Resistant Prostatic CancerAndrogen-Independent Prostatic CancerAndrogen-Insensitive Prostatic Cancer+14 more
MacroGenics 192
Testing effectiveness (Phase 2)Study completedNCT03625323
What this trial is testing

Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC

Who this might be right for
NSCLCHNSCC
Immutep S.A.S. 187
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT02971956
What this trial is testing

Pembrolizumab in Refractory Advanced Esophageal Cancer

Who this might be right for
Esophageal CancerSquamous Cell Esophagus CancerAdenocarcinoma Esophagus
Dana-Farber Cancer Institute 49
Early research (Phase 1)Ended earlyNCT04348916
What this trial is testing

Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid Tumors

Who this might be right for
CancerMelanomaSolid Tumor+7 more
Oncorus, Inc. 66
Early research (Phase 1)Study completedNCT02013154
What this trial is testing

DKN-01 in Combination With Paclitaxel or Pembrolizumab

Who this might be right for
Esophageal NeoplasmsAdenocarcinoma of the Gastroesophageal JunctionGastroesophageal Cancer+2 more
Leap Therapeutics, Inc. 151
Early research (Phase 1)Study completedNCT03739931
What this trial is testing

Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies

Who this might be right for
Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or LymphomaDose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma
ModernaTX, Inc. 134
Large-scale testing (Phase 3)Study completedNCT00206219
What this trial is testing

Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX)

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
AstraZeneca 477
Not applicableUnknownNCT04279509
What this trial is testing

Selecting Chemotherapy With High-throughput Drug Screen Assay Using Patient Derived Organoids in Patients With Refractory Solid Tumours (SCORE)

Who this might be right for
OrganoidsHNSCCEpithelial Ovarian Cancer+1 more
National University Hospital, Singapore 35
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