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Results for “Refractory Head and Neck Squamous Cell Carcinoma”

93 trials

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Showing 20 of 93 results

Early research (Phase 1)Study completedNCT03538028
What this trial is testing

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies

Who this might be right for
Cervical CancerMicrosatellite Instability (MSI)-High Endometrial CancerGastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])+14 more
Incyte Biosciences International Sàrl 22
Not applicableUnknownNCT03917537
What this trial is testing

WGA in Platinum-refractory HNSCC Underwent Nivolumab

Who this might be right for
HNSCC
Chang Gung Memorial Hospital 80
Early research (Phase 1)Ended earlyNCT04348916
What this trial is testing

Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid Tumors

Who this might be right for
CancerMelanomaSolid Tumor+7 more
Oncorus, Inc. 66
Testing effectiveness (Phase 2)Ended earlyNCT05099549
What this trial is testing

Safety, Tolerability, and Anti-Tumor Activity of AFM24 in Combination With SNK01 in Subjects With Advanced/Metastatic EGFR-Expressing Cancers

Who this might be right for
Squamous Cell Carcinoma of Head and NeckCarcinoma, Non-Small-Cell LungColorectal Neoplasms+3 more
NKGen Biotech, Inc. 11
Testing effectiveness (Phase 2)WithdrawnNCT04058145
What this trial is testing

AMD3100 Plus Pembrolizumab in Immune Checkpoint Blockade Refractory Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Cancer
Massachusetts General Hospital
Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
Large-scale testing (Phase 3)Study completedNCT00206219
What this trial is testing

Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX)

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
AstraZeneca 477
Early research (Phase 1)Looking for participantsNCT05859074
What this trial is testing

MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

Who this might be right for
Cutaneous Squamous Cell CarcinomaSCC - Squamous Cell CarcinomaBasal Cell Carcinoma+16 more
Memorial Sloan Kettering Cancer Center 56
Large-scale testing (Phase 3)Study completedNCT02105636
What this trial is testing

Trial of Nivolumab vs Therapy of Investigator's Choice in Recurrent or Metastatic Head and Neck Carcinoma (CheckMate 141)

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
Bristol-Myers Squibb 361
Early research (Phase 1)Study completedNCT00625456
What this trial is testing

Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors

Who this might be right for
MelanomaLung CancerRenal Cell Carcinoma+1 more
Jennerex Biotherapeutics 23
Early research (Phase 1)Looking for participantsNCT04777994
What this trial is testing

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

Who this might be right for
Advanced Solid Tumor Cancer
Calico Life Sciences LLC 248
Early research (Phase 1)Study completedNCT00004065
What this trial is testing

Chemotherapy in Treating Patients With Refractory Advanced Solid Tumors or Hematologic Cancer

Who this might be right for
Bladder CancerBreast CancerColorectal Cancer+9 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Looking for participantsNCT04119024
What this trial is testing

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmMetastatic MelanomaPathologic Stage IIIC Cutaneous Melanoma AJCC v8+14 more
Anusha Kalbasi 18
Early research (Phase 1)Enrolling By InvitationNCT07218003
What this trial is testing

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

Who this might be right for
Non Small Cell Lung CancerCervical CancerHead and Neck Squamous Cell Cancer+7 more
Rondo Therapeutics 149
Early research (Phase 1)Looking for participantsNCT05039801
What this trial is testing

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Who this might be right for
Advanced Endometrial CarcinomaAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Malignant Solid Neoplasm+35 more
M.D. Anderson Cancer Center 54
Early research (Phase 1)Study completedNCT03739931
What this trial is testing

Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies

Who this might be right for
Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or LymphomaDose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma
ModernaTX, Inc. 134
Early research (Phase 1)Study completedNCT01976741
What this trial is testing

Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)

Who this might be right for
Neoplasms
Bayer 168
Large-scale testing (Phase 3)Study completedNCT01166542
What this trial is testing

Efficacy Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Platinum-Refractory Head and Neck Cancers

Who this might be right for
Carcinoma, Squamous Cell of the Head and Neck
Oncolytics Biotech 167
Early research (Phase 1)Study completedNCT01017185
What this trial is testing

Study of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial Lesions

Who this might be right for
Refractory Head and Neck CancerSquamous Cell Carcinoma, SkinCarcinoma of the Breast+1 more
Takara Bio Inc. 28
Early research (Phase 1)Study completedNCT01520389
What this trial is testing

Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment

Who this might be right for
Advanced Solid TumorsColorectal CancerSquamous Cell Head and Neck Cancer+2 more
Merrimack Pharmaceuticals 112
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