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Results for “Refractory Head and Neck Squamous Cell Carcinoma”

92 trials

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Showing 20 of 92 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07272291
What this trial is testing

A Phase II Study of Toripalimab Plus Chemotherapy and Low-Dose Radiotherapy for Neoadjuvant Therapy-Refractory Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
Tianjin Medical University Cancer Institute and Hospital 48
Testing effectiveness (Phase 2)Ended earlyNCT03320629
What this trial is testing

Apatinib Plus Radiotherapy and S-1 for Treatment of Refractory or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Refractory or Metastatic Esophageal Squamous Cell Carcinoma
Hebei Medical University Fourth Hospital 7
Testing effectiveness (Phase 2)Ended earlyNCT05551117
What this trial is testing

Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors

Who this might be right for
Castration-Resistant Prostatic CancerAndrogen-Independent Prostatic CancerAndrogen-Insensitive Prostatic Cancer+14 more
MacroGenics 192
Testing effectiveness (Phase 2)Active Not RecruitingNCT04152499
What this trial is testing

Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)

Who this might be right for
Epithelial Ovarian CancerGastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma+7 more
Klus Pharma Inc. 1,410
Large-scale testing (Phase 3)Study completedNCT01166542
What this trial is testing

Efficacy Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Platinum-Refractory Head and Neck Cancers

Who this might be right for
Carcinoma, Squamous Cell of the Head and Neck
Oncolytics Biotech 167
Testing effectiveness (Phase 2)Study completedNCT02971956
What this trial is testing

Pembrolizumab in Refractory Advanced Esophageal Cancer

Who this might be right for
Esophageal CancerSquamous Cell Esophagus CancerAdenocarcinoma Esophagus
Dana-Farber Cancer Institute 49
Early research (Phase 1)Study completedNCT00004065
What this trial is testing

Chemotherapy in Treating Patients With Refractory Advanced Solid Tumors or Hematologic Cancer

Who this might be right for
Bladder CancerBreast CancerColorectal Cancer+9 more
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT02345330
What this trial is testing

Trial of pIL-12 Electroporation in Squamous Cell Carcinoma of the Head and Neck (IL12HNSCC)

Who this might be right for
Head and Neck Squamous Cell Carcinoma
OncoSec Medical Incorporated 4
Testing effectiveness (Phase 2)Study completedNCT03997968
What this trial is testing

CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors

Who this might be right for
MalignancyNon-hodgkin LymphomaMultiple Myeloma+12 more
Cyteir Therapeutics, Inc. 169
Early research (Phase 1)Study completedNCT02145637
What this trial is testing

Phase I Study of the Combination of Afatinib and Ruxolitinib in Patients With Treatment-refractory Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
NSCLC
Yonsei University 30
Early research (Phase 1)Study completedNCT01017185
What this trial is testing

Study of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial Lesions

Who this might be right for
Refractory Head and Neck CancerSquamous Cell Carcinoma, SkinCarcinoma of the Breast+1 more
Takara Bio Inc. 28
Testing effectiveness (Phase 2)Study completedNCT03625323
What this trial is testing

Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC

Who this might be right for
NSCLCHNSCC
Immutep S.A.S. 187
Early research (Phase 1)Study completedNCT02013154
What this trial is testing

DKN-01 in Combination With Paclitaxel or Pembrolizumab

Who this might be right for
Esophageal NeoplasmsAdenocarcinoma of the Gastroesophageal JunctionGastroesophageal Cancer+2 more
Leap Therapeutics, Inc. 151
Testing effectiveness (Phase 2)Ended earlyNCT02213133
What this trial is testing

Selinexor Treatment of Advanced Relapsed/Refractory Squamous Cell Carcinomas

Who this might be right for
Squamous Cell Carcinoma
Karyopharm Therapeutics Inc 45
Testing effectiveness (Phase 2)Looking for participantsNCT07070518
What this trial is testing

Study of GV20-0251 in Participants With Solid Tumor Malignancies

Who this might be right for
Solid Tumor CancerAdult Refractory CancerEndometrial Carcinoma (EC)+6 more
GV20 Therapeutics 350
Testing effectiveness (Phase 2)Study completedNCT00006033
What this trial is testing

Interleukin-2 Gene or Methotrexate in Treating Patients With Recurrent or Refractory Stage III or Stage IV Head and Neck Cancer

Who this might be right for
Head and Neck Cancer
H. Lee Moffitt Cancer Center and Research Institute
Large-scale testing (Phase 3)Looking for participantsNCT06589804
What this trial is testing

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

Who this might be right for
Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell CarcinomaMetastatic Laryngeal Squamous Cell Carcinoma+18 more
National Cancer Institute (NCI) 158
Early research (Phase 1)Looking for participantsNCT04119024
What this trial is testing

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmMetastatic MelanomaPathologic Stage IIIC Cutaneous Melanoma AJCC v8+14 more
Anusha Kalbasi 18
Testing effectiveness (Phase 2)Study completedNCT02335918
What this trial is testing

A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck (SCCHN)Ovarian Carcinoma-Enrollment CompletedColorectal Cancer (CRC)-Enrollment Completed+2 more
Celldex Therapeutics 175
Early research (Phase 1)Ended earlyNCT04762225
What this trial is testing

RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors and Melanoma

Who this might be right for
Head and Neck Squamous Cell CarcinomaMelanomaCervical Cancer
Repertoire Immune Medicines 7
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