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Results for “Refractory Hepatoblastoma”

39 trials

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Showing 20 of 39 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Very early researchTemporarily pausedNCT05756660
What this trial is testing

Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Who this might be right for
Ototoxicity, Drug-Induced
Children's Hospital Medical Center, Cincinnati 33
Testing effectiveness (Phase 2)Study completedNCT03220035
What this trial is testing

Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 4
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT06521567
What this trial is testing

Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Who this might be right for
MelanomaHodgkin LymphomaHigh and Low Grade Glioma+9 more
GlaxoSmithKline 83
Testing effectiveness (Phase 2)UnknownNCT00287976
What this trial is testing

Irinotecan in Treating Young Patients With Refractory or Recurrent Hepatoblastoma

Who this might be right for
Liver Cancer
Children's Cancer and Leukaemia Group 30
Early research (Phase 1)Study completedNCT02085148
What this trial is testing

A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy

Who this might be right for
Pediatric Oncology
Bayer 62
Testing effectiveness (Phase 2)Study completedNCT01154816
What this trial is testing

Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
HepatoblastomaPreviously Treated Childhood RhabdomyosarcomaRecurrent Childhood Acute Lymphoblastic Leukemia+8 more
Children's Oncology Group 118
Testing effectiveness (Phase 2)Study completedNCT03213665
What this trial is testing

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Hodgkin LymphomaAnn Arbor Stage III Non-Hodgkin Lymphoma+38 more
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)WithdrawnNCT02011126
What this trial is testing

Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
HepatoblastomaPreviously Treated Childhood RhabdomyosarcomaRecurrent Childhood Liver Cancer+5 more
Children's Oncology Group
Early research (Phase 1)Active Not RecruitingNCT04483778
What this trial is testing

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Who this might be right for
Pediatric Solid TumorGerm Cell TumorRetinoblastoma+14 more
Seattle Children's Hospital 68
Not applicableLooking for participantsNCT07188311
What this trial is testing

Pucotenlimab Combined With Lenvatinib and Chemotherapy in the Treatment of Advanced, Relapsed/Refractory Hepatoblastoma in Children

Who this might be right for
HepatoblastomaPediatric Cancer
Sun Yat-sen University 24
Early research (Phase 1)Study completedNCT02390843
What this trial is testing

Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors

Who this might be right for
RetinoblastomaClear Cell SarcomaRenal Cell Carcinoma+9 more
Emory University 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT04195555
What this trial is testing

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Recurrent EpendymomaRecurrent Ewing SarcomaRecurrent Hepatoblastoma+30 more
National Cancer Institute (NCI) 3
Testing effectiveness (Phase 2)Study completedNCT01125800
What this trial is testing

A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB

Who this might be right for
MedulloblastomaRhabdomyosarcomaNeuroblastoma+3 more
Novartis Pharmaceuticals 76
Early research (Phase 1)Looking for participantsNCT04308330
What this trial is testing

Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies

Who this might be right for
Ewing SarcomaRhabdomyosarcomaWilms Tumor+3 more
New York Medical College 30
Testing effectiveness (Phase 2)Looking for participantsNCT04901702
What this trial is testing

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Who this might be right for
Recurrent Solid TumorRecurrent Ewing SarcomaRecurrent Hepatoblastoma+19 more
St. Jude Children's Research Hospital 90
Not applicableLooking for participantsNCT05556642
What this trial is testing

Relapsed and Refractory Hepatoblastoma: A Prospective Registry and Liver Tumor Research Consortium Initiative

Who this might be right for
Relapsed HepatoblastomaRefractory Hepatoblastoma
Children's Hospital Medical Center, Cincinnati 500
Testing effectiveness (Phase 2)Study completedNCT03233204
What this trial is testing

Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+33 more
National Cancer Institute (NCI) 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213704
What this trial is testing

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor+30 more
National Cancer Institute (NCI) 9
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