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Results for “Refractory Hepatoblastoma”

39 trials

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Showing 20 of 39 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)WithdrawnNCT02011126
What this trial is testing

Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
HepatoblastomaPreviously Treated Childhood RhabdomyosarcomaRecurrent Childhood Liver Cancer+5 more
Children's Oncology Group
Testing effectiveness (Phase 2)Study completedNCT01125800
What this trial is testing

A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB

Who this might be right for
MedulloblastomaRhabdomyosarcomaNeuroblastoma+3 more
Novartis Pharmaceuticals 76
Early research (Phase 1)Study completedNCT02085148
What this trial is testing

A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy

Who this might be right for
Pediatric Oncology
Bayer 62
Testing effectiveness (Phase 2)Looking for participantsNCT04851119
What this trial is testing

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Who this might be right for
Colorectal CarcinomaEndometrial CarcinomaMelanoma+19 more
Children's Oncology Group 147
Testing effectiveness (Phase 2)Looking for participantsNCT04901702
What this trial is testing

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Who this might be right for
Recurrent Solid TumorRecurrent Ewing SarcomaRecurrent Hepatoblastoma+19 more
St. Jude Children's Research Hospital 90
Testing effectiveness (Phase 2)Study completedNCT00831844
What this trial is testing

Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
Adult RhabdomyosarcomaAdult Synovial SarcomaChildhood Hepatoblastoma+13 more
National Cancer Institute (NCI) 116
Not applicableLooking for participantsNCT05556642
What this trial is testing

Relapsed and Refractory Hepatoblastoma: A Prospective Registry and Liver Tumor Research Consortium Initiative

Who this might be right for
Relapsed HepatoblastomaRefractory Hepatoblastoma
Children's Hospital Medical Center, Cincinnati 500
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213704
What this trial is testing

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor+30 more
National Cancer Institute (NCI) 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT04284774
What this trial is testing

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Malignant Solid NeoplasmRecurrent Adrenal Gland PheochromocytomaRecurrent Ectomesenchymoma+38 more
National Cancer Institute (NCI) 5
Testing effectiveness (Phase 2)Study completedNCT03213678
What this trial is testing

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+30 more
National Cancer Institute (NCI) 18
Not applicableLooking for participantsNCT07188311
What this trial is testing

Pucotenlimab Combined With Lenvatinib and Chemotherapy in the Treatment of Advanced, Relapsed/Refractory Hepatoblastoma in Children

Who this might be right for
HepatoblastomaPediatric Cancer
Sun Yat-sen University 24
Testing effectiveness (Phase 2)UnknownNCT00287976
What this trial is testing

Irinotecan in Treating Young Patients With Refractory or Recurrent Hepatoblastoma

Who this might be right for
Liver Cancer
Children's Cancer and Leukaemia Group 30
Testing effectiveness (Phase 2)Looking for participantsNCT04634357
What this trial is testing

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

Who this might be right for
HepatoblastomaHepatocellular Carcinoma (HCC)Liver Neoplasms+3 more
Eureka Therapeutics Inc. 15
Testing effectiveness (Phase 2)Study completedNCT01154816
What this trial is testing

Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
HepatoblastomaPreviously Treated Childhood RhabdomyosarcomaRecurrent Childhood Acute Lymphoblastic Leukemia+8 more
Children's Oncology Group 118
Testing effectiveness (Phase 2)Active Not RecruitingNCT03155620
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+42 more
National Cancer Institute (NCI) 1,376
Early research (Phase 1)Active Not RecruitingNCT04483778
What this trial is testing

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Who this might be right for
Pediatric Solid TumorGerm Cell TumorRetinoblastoma+14 more
Seattle Children's Hospital 68
Not applicableStudy completedNCT00002485
What this trial is testing

Development of Strategies to Increase Enrollment in Clinical Trials for Children With Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
Children's Oncology Group 359
Early research (Phase 1)Study completedNCT00007813
What this trial is testing

Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+5 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 21
Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
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