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Results for “Refractory Large B-cell Lymphoma (LBCL)”

31 trials

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Showing 20 of 31 results

Testing effectiveness (Phase 2)Looking for participantsNCT07538635
What this trial is testing

CAR-T Combined With ASCT in the Treatment of Relapsed/Refractory Large B-cell Lymphoma With High-risk Factors.

Who this might be right for
High-risk R/R LBCL
Zhejiang Cancer Hospital 20
Early research (Phase 1)Study completedNCT03939026
What this trial is testing

Safety and Efficacy of ALLO-501 Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell or Follicular Lymphoma

Who this might be right for
Relapsed/Refractory Large B Cell LymphomaRelapsed/Refractory Follicular Lymphoma
Allogene Therapeutics 50
Testing effectiveness (Phase 2)Looking for participantsNCT06526793
What this trial is testing

Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

Who this might be right for
B-cell Non-Hodgkin LymphomaFollicular Lymphoma (FL)Large B-Cell Lymphoma (LBCL)
AstraZeneca 270
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07774234
What this trial is testing

Sonrotoclax, Glofitamab, Gemcitabine, and Oxaliplatin for Relapsed or Refractory Large B-Cell Lymphoma

Who this might be right for
Large B-Cell Lymphoma (LBCL)High-grade B-cell Lymphoma
The First Affiliated Hospital of Soochow University 39
Not applicableLooking for participantsNCT07524816
What this trial is testing

Real World Practice With Academic Anti CD19 CAR-T Cell Therapy in Relapse/Refractory B-cell Lymphoma

Who this might be right for
Large B-Cell Lymphoma (LBCL)
N.N. Alexandrov National Cancer Centre 76
Testing effectiveness (Phase 2)Ended earlyNCT05714345
What this trial is testing

Evaluation of Lymphodepletion With ALLO-647 in Adults With R/R Large B Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy

Who this might be right for
Relapsed/Refractory Large B Cell Lymphoma
Allogene Therapeutics 2
Testing effectiveness (Phase 2)Ended earlyNCT05972720
What this trial is testing

Firi-cel in Patients With Relapsed/Refractory Large B-cell Lymphoma

Who this might be right for
CancerRelapsed/Refractory Large B-cell Lymphoma (LBCL)
CARGO Therapeutics 101
Testing effectiveness (Phase 2)Looking for participantsNCT07240194
What this trial is testing

The Efficacy and Safety of Glofitamab in Combination With PD-1 Antibody and Lenalidomide in Patients With Relapsed/Refractory Large B-cell Lymphoma (LBCL) With TP53 Aberrations: A Prospective, Multicenter, Phase II Clinical Study

Who this might be right for
Large B-cell LymphomaTP53
The First Affiliated Hospital with Nanjing Medical University 24
Testing effectiveness (Phase 2)Looking for participantsNCT06479356
What this trial is testing

CD19-targeted CAR T Cells for Relapsed or Refractory (R/R) Large B-cell Lymphoma

Who this might be right for
Non-Hodgkin LymphomaLarge B-cell Lymphoma
Shanghai Ming Ju Biotechnology Co., Ltd. 12
Large-scale testing (Phase 3)Ended earlyNCT05664217
What this trial is testing

NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma

Who this might be right for
Non-Hodgkin LymphomaRelapsed/Refractory Diffuse Large B-cell Lymphoma
Nektar Therapeutics 15
Testing effectiveness (Phase 2)Looking for participantsNCT06104592
What this trial is testing

Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL

Who this might be right for
Large B-cell LymphomaRelapsed Non-Hodgkin Lymphoma
H. Lee Moffitt Cancer Center and Research Institute 27
Early research (Phase 1)Study completedNCT05359211
What this trial is testing

NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent Grade 3b Follicular Lymphoma+6 more
Fred Hutchinson Cancer Center 27
Not applicableUnknownNCT05800067
What this trial is testing

Axi-cel Retreatment in Relapsed/Refractory LBCL

Who this might be right for
CAR-T Retreatment
Ruijin Hospital 32
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07823829
What this trial is testing

A Phase I/II Trial of CT1190B in Patients With Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Large B-Cell Lymphoma (LBCL)
UCARsgen Biotech Limited 68
Testing effectiveness (Phase 2)Temporarily pausedNCT07098364
What this trial is testing

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent Grade 3b Follicular Lymphoma+9 more
Fred Hutchinson Cancer Center 33
Testing effectiveness (Phase 2)Looking for participantsNCT06905509
What this trial is testing

Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements+11 more
University of California, Davis
Early research (Phase 1)Ended earlyNCT06256484
What this trial is testing

Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Who this might be right for
Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
Atara Biotherapeutics 1
Testing effectiveness (Phase 2)Looking for participantsNCT07788118
What this trial is testing

A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7×19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Relapsed/Refractory Large B-cell Lymphoma (LBCL)Diffuse Large B-Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+2 more
Second Affiliated Hospital, Zhejiang University, School of Medicine 70
Testing effectiveness (Phase 2)Looking for participantsNCT06542250
What this trial is testing

Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

Who this might be right for
B-cell Malignancies
AstraZeneca 174
Testing effectiveness (Phase 2)Active Not RecruitingNCT04416984
What this trial is testing

Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell Lymphoma, Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (ALPHA2)

Who this might be right for
Relapsed or Refractory Large B Cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small Lymphocytic Lymphoma
Allogene Therapeutics 160
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