Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Refractory Malignancy”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Ended earlyNCT03117361
What this trial is testing

Trial of Plitidepsin (Aplidin®) in Combination With Bortezomib and Dexamethasone in Multiple Myeloma Patients Double Refractory to Bortezomib and Lenalidomide

Who this might be right for
Multiple Myeloma
PharmaMar 10
Testing effectiveness (Phase 2)Study completedNCT00151086
What this trial is testing

Oral Estramustine and Oral Vinorelbine in the Treatment of Hormone-Refractory Prostate Cancer

Who this might be right for
Prostate Cancer
University of Michigan Rogel Cancer Center 33
Testing effectiveness (Phase 2)Study completedNCT00516295
What this trial is testing

Vincristine Sulfate, Topotecan Hydrochloride, and Cyclophosphamide With or Without Bevacizumab in Treating Young Patients With Refractory or First Recurrent Extracranial Ewing Sarcoma

Who this might be right for
Ewing Sarcoma of BoneExtraosseous Ewing SarcomaPeripheral Primitive Neuroectodermal Tumor+1 more
National Cancer Institute (NCI) 7
Testing effectiveness (Phase 2)Ended earlyNCT03648372
What this trial is testing

TAK-981 in People With Advanced Solid Tumors or Cancers in the Immune System

Who this might be right for
NeoplasmsLymphomaHematologic Neoplasms
Takeda 109
Early research (Phase 1)Study completedNCT03538028
What this trial is testing

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies

Who this might be right for
Cervical CancerMicrosatellite Instability (MSI)-High Endometrial CancerGastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])+14 more
Incyte Biosciences International Sàrl 22
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07774234
What this trial is testing

Sonrotoclax, Glofitamab, Gemcitabine, and Oxaliplatin for Relapsed or Refractory Large B-Cell Lymphoma

Who this might be right for
Large B-Cell Lymphoma (LBCL)High-grade B-cell Lymphoma
The First Affiliated Hospital of Soochow University 39
Early research (Phase 1)Study completedNCT00932698
What this trial is testing

Study of Oral Ixazomib in Adult Participants With Relapsed and/or Refractory (RR) Multiple Myeloma

Who this might be right for
Relapsed and Refractory Multiple Myeloma
Millennium Pharmaceuticals, Inc. 60
Early research (Phase 1)Study completedNCT00087204
What this trial is testing

Rebeccamycin Analog in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+13 more
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Study completedNCT00435084
What this trial is testing

A Phase I/II Study to Assess the Safety and Tolerability of APO866 for the Treatment of Refractory B-CLL

Who this might be right for
B-cell Chronic Lymphocytic Leukemia
Valerio Therapeutics 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06416930
What this trial is testing

Study of Cadonilimab Combined With Chemotherapy in Recurrent / Refractory Pleural Mesothelioma

Who this might be right for
Pleural Mesothelioma
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 59
Large-scale testing (Phase 3)Active Not RecruitingNCT06413498
What this trial is testing

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Kite, A Gilead Company 452
Testing effectiveness (Phase 2)Study completedNCT01741116
What this trial is testing

Dovitinib(TKI258) in Patients With Castration-resistant Prostate Cancer

Who this might be right for
Hormone Refractory Prostate Cancer
Korean Cancer Study Group 44
Testing effectiveness (Phase 2)Ended earlyNCT00493857
What this trial is testing

Study of Nimotuzumab and Irinotecan in Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
YM BioSciences 100
Testing effectiveness (Phase 2)Study completedNCT02572167
What this trial is testing

Brentuximab Vedotin Combined With Nivolumab for Relapsed or Refractory Hodgkin Lymphoma

Who this might be right for
Hodgkin Lymphoma
Seagen Inc. 93
Early research (Phase 1)Study completedNCT01270698
What this trial is testing

Study of IMMU-130 in Patients With Relapsed/Refractory Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Gilead Sciences 26
Not applicableEnded earlyNCT00651716
What this trial is testing

T Cells in Predicting Acute Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersGestational Trophoblastic Tumor+8 more
Vanderbilt-Ingram Cancer Center 150
Testing effectiveness (Phase 2)Looking for participantsNCT06532084
What this trial is testing

Sorafenib Relapase Prophylaxis After HCT With PTBCy Regimen

Who this might be right for
Acute Myeloid Leukemia, in RelapseMyelodysplastic SyndromesChronic Myeloid Leukemia+1 more
St. Petersburg State Pavlov Medical University 88
Early research (Phase 1)Looking for participantsNCT06690827
What this trial is testing

Clinical Trial of CD123-targeted CAR-NK Therapy for Relapse/Refractory AML or BPDCN

Who this might be right for
AML (Acute Myeloid Leukemia)BPDCN (Blastic Plasmacytoid Dendritic Cell Neoplasm)
Chongqing Precision Biotech Co., Ltd 30
Testing effectiveness (Phase 2)Study completedNCT00939627
What this trial is testing

Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab

Who this might be right for
Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell CarcinomaRecurrent Metastatic Squamous Neck Cancer With Occult PrimaryRecurrent Salivary Gland Cancer+34 more
National Cancer Institute (NCI) 55
Not applicableNo Longer AvailableNCT03706573
What this trial is testing

Managed Access Program to Provide Alpelisib for Patients With HR+ Advanced or Metastatic Breast Cancer

Who this might be right for
HR+ Advanced or Metastatic Breast Cancer
Novartis Pharmaceuticals
Next Page