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Results for “Refractory Malignant Brain Neoplasm”

92 trials

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Showing 20 of 92 results

Early research (Phase 1)Study completedNCT00006246
What this trial is testing

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorLeukemia+4 more
Pediatric Brain Tumor Consortium 28
Testing effectiveness (Phase 2)Study completedNCT04238819
What this trial is testing

Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Who this might be right for
Relapsed Solid TumorRefractory Solid Tumor
Eli Lilly and Company 47
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Testing effectiveness (Phase 2)Study completedNCT01462695
What this trial is testing

Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma

Who this might be right for
Childhood Cerebellar Anaplastic AstrocytomaChildhood Cerebral Anaplastic AstrocytomaChildhood Cerebral Astrocytoma+8 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Early research (Phase 1)Study completedNCT04430842
What this trial is testing

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Who this might be right for
AstrocytomaBrain CancerBrain Metastases+20 more
Quadriga Biosciences, Inc. 15
Early research (Phase 1)Looking for participantsNCT05857969
What this trial is testing

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

Who this might be right for
Recurrent Childhood Acute Myeloid LeukemiaRecurrent Childhood Acute Lymphoblastic LeukemiaRecurrent Childhood Large Cell Lymphoma+15 more
Florida International University 65
Testing effectiveness (Phase 2)Study completedNCT02052648
What this trial is testing

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

Who this might be right for
Glioblastoma MultiformeGliomaGliosarcoma+1 more
NewLink Genetics Corporation 160
Testing effectiveness (Phase 2)Study completedNCT00528437
What this trial is testing

Temozolomide,Thiotepa and Carboplatin With Autologous Stem Cell Rescue Followed by 13-cis-retinoic Acid in Patients With Recurrent/Refractory Malignant Brain Tumors

Who this might be right for
Brain Tumors
NYU Langone Health 46
Testing effectiveness (Phase 2)Study completedNCT00095940
What this trial is testing

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

Who this might be right for
Recurrent Childhood Anaplastic AstrocytomaRecurrent Childhood Brain Stem GliomaRecurrent Childhood Ependymoma+5 more
National Cancer Institute (NCI) 52
Early research (Phase 1)Looking for participantsNCT04510051
What this trial is testing

CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children

Who this might be right for
Malignant Brain NeoplasmRecurrent Malignant Brain NeoplasmRefractory Malignant Brain Neoplasm
City of Hope Medical Center 18
Early research (Phase 1)Study completedNCT00002750
What this trial is testing

Melphalan in Patients With Neoplastic Meningitis

Who this might be right for
Brain and Central Nervous System TumorsExtragonadal Germ Cell TumorLeukemia+2 more
Duke University 6
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Early research (Phase 1)Study completedNCT00418327
What this trial is testing

Safety Study of Tarceva in Children With Refractory and Relapsed Malignant Brain Tumors and Newly Diagnosed Brain Stem Glioma

Who this might be right for
Malignant Brain TumorBrain Stem Glioma,
Gustave Roussy, Cancer Campus, Grand Paris 48
Early research (Phase 1)Study completedNCT00003876
What this trial is testing

Internal Radiation Therapy Plus Carmustine Implants in Treating Patients With Recurrent or Refractory Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Barrett Cancer Center
Early research (Phase 1)Study completedNCT00004212
What this trial is testing

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsLymphomaUnspecified Childhood Solid Tumor, Protocol Specific
Daiichi Sankyo
Testing effectiveness (Phase 2)Study completedNCT00008008
What this trial is testing

Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Herbert Irving Comprehensive Cancer Center 40
Early research (Phase 1)Study completedNCT02271711
What this trial is testing

Expanded Natural Killer Cell Infusion in Treating Younger Patients With Recurrent/Refractory Brain Tumors

Who this might be right for
Recurrent Childhood MedulloblastomaRecurrent EpendymomaRecurrent Medulloblastoma
M.D. Anderson Cancer Center 12
Not applicableStudy completedNCT02162732
What this trial is testing

Molecular-Guided Therapy for Childhood Cancer

Who this might be right for
NeuroblastomaMedulloblastomaGlioma+16 more
Giselle Sholler 186
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