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Results for “Refractory Malignant Brain Neoplasm”

92 trials

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Showing 20 of 92 results

Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Testing effectiveness (Phase 2)Study completedNCT00268359
What this trial is testing

Bevacizumab and Irinotecan in Treating Patients With Recurrent or Refractory Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
Duke University 68
Testing effectiveness (Phase 2)Ended earlyNCT00788125
What this trial is testing

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
City of Hope Medical Center 7
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Testing effectiveness (Phase 2)Study completedNCT02684058
What this trial is testing

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Who this might be right for
Diffuse AstrocytomaAnaplastic AstrocytomaAstrocytoma+19 more
Novartis Pharmaceuticals 151
Early research (Phase 1)Study completedNCT01082926
What this trial is testing

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Meningioma+11 more
City of Hope Medical Center 6
Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Early research (Phase 1)Study completedNCT00077454
What this trial is testing

Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Previously Treated Childhood RhabdomyosarcomaRecurrent Childhood Brain TumorRecurrent Childhood Cerebellar Astrocytoma+9 more
National Cancer Institute (NCI) 95
Testing effectiveness (Phase 2)UnknownNCT02839954
What this trial is testing

CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor

Who this might be right for
Hepatocellular CarcinomaNon-small Cell Lung CancerPancreatic Carcinoma+4 more
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
Early research (Phase 1)Study completedNCT02271711
What this trial is testing

Expanded Natural Killer Cell Infusion in Treating Younger Patients With Recurrent/Refractory Brain Tumors

Who this might be right for
Recurrent Childhood MedulloblastomaRecurrent EpendymomaRecurrent Medulloblastoma
M.D. Anderson Cancer Center 12
Early research (Phase 1)Study completedNCT01158300
What this trial is testing

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 28
Testing effectiveness (Phase 2)Looking for participantsNCT01269853
What this trial is testing

Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

Who this might be right for
Glioblastoma MultiformeAnaplastic Astrocytoma
Northwell Health 54
Early research (Phase 1)WithdrawnNCT00458744
What this trial is testing

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Children's Oncology Group
Testing effectiveness (Phase 2)Study completedNCT02095132
What this trial is testing

Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
Central Nervous System Embryonal Tumor With Rhabdoid FeaturesCentral Nervous System Embryonal Tumor, Not Otherwise SpecifiedCentral Nervous System Ganglioneuroblastoma+12 more
National Cancer Institute (NCI) 76
Testing effectiveness (Phase 2)Ended earlyNCT00014443
What this trial is testing

Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Rush University Medical Center 5
Testing effectiveness (Phase 2)Looking for participantsNCT06640582
What this trial is testing

TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas

Who this might be right for
Brain TumorBrain MetastasesBrain Cancer+4 more
Essen Biotech 85
Early research (Phase 1)Study completedNCT00730613
What this trial is testing

Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
City of Hope Medical Center 3
Early research (Phase 1)Study completedNCT01453283
What this trial is testing

Tabectedin to Treat Children and Adolescents With Cancer

Who this might be right for
Solid Tumors
National Cancer Institute (NCI) 12
Early research (Phase 1)Study completedNCT00363272
What this trial is testing

Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
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