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Results for “Refractory Malignant Glioma”

123 trials

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Showing 20 of 123 results

Early research (Phase 1)Study completedNCT04334863
What this trial is testing

WP1066 in Children With Refractory and Progressive or Recurrent Malignant Brain Tumors

Who this might be right for
Brain TumorMedulloblastomaBrain Metastases
Emory University 10
Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Testing effectiveness (Phase 2)Study completedNCT00679354
What this trial is testing

Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy

Who this might be right for
Childhood High-grade Cerebellar AstrocytomaChildhood High-grade Cerebral AstrocytomaRecurrent Childhood Anaplastic Astrocytoma+7 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Study completedNCT00003597
What this trial is testing

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Who this might be right for
Cancer
Children's Oncology Group 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT02465060
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmBladder Carcinoma+49 more
National Cancer Institute (NCI) 6,452
Testing effectiveness (Phase 2)Ended earlyNCT03690869
What this trial is testing

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Who this might be right for
Relapsed Solid TumorRefractory Solid TumorRelapsed Central Nervous System Tumor+3 more
Regeneron Pharmaceuticals 57
Testing effectiveness (Phase 2)Looking for participantsNCT01269853
What this trial is testing

Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

Who this might be right for
Glioblastoma MultiformeAnaplastic Astrocytoma
Northwell Health 54
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Testing effectiveness (Phase 2)Ended earlyNCT00003535
What this trial is testing

Antineoplaston Therapy in Treating Children With Recurrent or Refractory High-Grade Glioma

Who this might be right for
High Grade Glioma
Burzynski Research Institute 9
Early research (Phase 1)Not Yet RecruitingNCT07331064
What this trial is testing

Gallium Maltolate for the Treatment of Pediatric Patients With Relapsed or Refractory Pediatric High-Grade Glioma and Atypical Teratoid Rhabdoid Tumor

Who this might be right for
High Grade GliomasAtypical Teratoid Rhabdoid Tumors (ATRT)Diffuse Midline Glioma+2 more
Sarah Rumler 15
Early research (Phase 1)Active Not RecruitingNCT03598244
What this trial is testing

Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

Who this might be right for
Recurrent Diffuse Intrinsic Pontine GliomaRecurrent Malignant GliomaRecurrent Medulloblastoma+5 more
National Cancer Institute (NCI) 41
Early research (Phase 1)Study completedNCT00074646
What this trial is testing

Phase I Trial of CC-8490 for the Treatment of Subjects With Recurrent/Refractory High-Grade Gliomas

Who this might be right for
GlioblastomaMalignant Gliomas
Celgene Corporation 36
Testing effectiveness (Phase 2)Looking for participantsNCT04870944
What this trial is testing

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Who this might be right for
Diffuse Midline Glioma, H3 K27-AlteredMetastatic Malignant Neoplasm in the Central Nervous SystemRecurrent Diffuse Intrinsic Pontine Glioma+7 more
Children's Oncology Group 63
Testing effectiveness (Phase 2)Study completedNCT03220035
What this trial is testing

Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 4
Early research (Phase 1)Active Not RecruitingNCT02208362
What this trial is testing

Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma

Who this might be right for
Recurrent GlioblastomaRecurrent Malignant GliomaRecurrent WHO Grade II Glioma+5 more
City of Hope Medical Center 65
Early research (Phase 1)Looking for participantsNCT03911388
What this trial is testing

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Who this might be right for
Neoplasms, BrainGlioblastoma MultiformeGlioblastoma of Cerebellum+30 more
M.D. Anderson Cancer Center 24
Testing effectiveness (Phase 2)Ended earlyNCT01517776
What this trial is testing

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents

Who this might be right for
Gliomas
Martin-Luther-Universität Halle-Wittenberg 28
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
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