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Results for “Refractory Malignant Glioma”

120 trials

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Showing 20 of 120 results

Early research (Phase 1)WithdrawnNCT00458744
What this trial is testing

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Children's Oncology Group
Testing effectiveness (Phase 2)Ended earlyNCT01836549
What this trial is testing

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAstrocytoma, Grade II+6 more
Pediatric Brain Tumor Consortium 43
Testing effectiveness (Phase 2)Ended earlyNCT00014443
What this trial is testing

Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Rush University Medical Center 5
Early research (Phase 1)Ended earlyNCT05429502
What this trial is testing

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Who this might be right for
Neuroblastoma
Novartis Pharmaceuticals 12
Testing effectiveness (Phase 2)UnknownNCT02839954
What this trial is testing

CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor

Who this might be right for
Hepatocellular CarcinomaNon-small Cell Lung CancerPancreatic Carcinoma+4 more
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)Ended earlyNCT01517776
What this trial is testing

Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents

Who this might be right for
Gliomas
Martin-Luther-Universität Halle-Wittenberg 28
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Testing effectiveness (Phase 2)Study completedNCT02824133
What this trial is testing

Treatment With AZD4547 for Recurrent Malignant Glioma Expressing FGFR-TACC Gene Fusion"

Who this might be right for
Recurrent IDHwt Gliomas With FGFR3-TACC3 FusionRecurrent IDHwt Gliomas With FGFR1-TACC1 Fusion
Assistance Publique - Hôpitaux de Paris 14
Testing effectiveness (Phase 2)Ended earlyNCT00003535
What this trial is testing

Antineoplaston Therapy in Treating Children With Recurrent or Refractory High-Grade Glioma

Who this might be right for
High Grade Glioma
Burzynski Research Institute 9
Early research (Phase 1)Ended earlyNCT04541225
What this trial is testing

Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors

Who this might be right for
GliomaGlioma, MalignantGlioma, Mixed+21 more
Nuvation Bio Inc. 74
Testing effectiveness (Phase 2)Study completedNCT02750891
What this trial is testing

DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas

Who this might be right for
GlioblastomaDiffuse Intrinsic Pontine Glioma
Sumitomo Pharma Co., Ltd. 18
Testing effectiveness (Phase 2)Study completedNCT00066248
What this trial is testing

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Who this might be right for
Brain TumorCentral Nervous System TumorsCachexia+5 more
University of South Florida 70
Testing effectiveness (Phase 2)Study completedNCT00528437
What this trial is testing

Temozolomide,Thiotepa and Carboplatin With Autologous Stem Cell Rescue Followed by 13-cis-retinoic Acid in Patients With Recurrent/Refractory Malignant Brain Tumors

Who this might be right for
Brain Tumors
NYU Langone Health 46
Early research (Phase 1)WithdrawnNCT05082493
What this trial is testing

A Multicenter, Study of the Safety and Pharmacokinetics of Intravenously Infused Berubicin in Pediatric Patients With Progressive, Refractory, or Recurrent High Grade Gliomas

Who this might be right for
High Grade Glioma
WPD Pharmaceuticals Sp. z o.o.
Early research (Phase 1)Study completedNCT00968240
What this trial is testing

Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab)

Who this might be right for
Glioblastoma MultiformeAnaplastic Astrocytoma
Northwell Health 30
Testing effectiveness (Phase 2)Looking for participantsNCT06838676
What this trial is testing

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Who this might be right for
Diffuse Intrinsic Pontine Gliomas (DIPG)Progressive DIPGRefractory DIPG+2 more
Nationwide Children's Hospital 60
Early research (Phase 1)Active Not RecruitingNCT02359565
What this trial is testing

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeLynch SyndromeMalignant Glioma+8 more
National Cancer Institute (NCI) 71
Early research (Phase 1)Study completedNCT00994500
What this trial is testing

Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System ChoriocarcinomaChildhood Central Nervous System Germ Cell Tumor+32 more
National Cancer Institute (NCI) 20
Post-approval studies (Phase 4)Ended earlyNCT04650204
What this trial is testing

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Who this might be right for
Intractable EpilepsyMalignant GliomaSeizure Disorder+2 more
Mayo Clinic 4
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