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Results for “Refractory Malignant Solid Neoplasm”

284 trials

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Showing 20 of 284 results

Early research (Phase 1)Study completedNCT01212341
What this trial is testing

Allogeneic Natural Killer (NK) Cell Therapy in Patients With Lymphoma or Solid Tumor

Who this might be right for
Malignant LymphomasSolid Tumors
Seoul National University Hospital 18
Testing effectiveness (Phase 2)Study completedNCT02116777
What this trial is testing

Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies

Who this might be right for
Adult Solid NeoplasmChildhood Solid NeoplasmRecurrent Childhood Central Nervous System Neoplasm+3 more
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439175
What this trial is testing

Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 70
Early research (Phase 1)Looking for participantsNCT07100210
What this trial is testing

A Clinical Trial Evaluating IL-22BP/LNP Compound in Refractory Malignant Solid Tumors for Safety, Tolerability and Activity

Who this might be right for
Refractory Malignant Solid TumorsmRNA VaccineInterleukin
Xingchen Peng 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT03878095
What this trial is testing

Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors

Who this might be right for
Malignant Solid NeoplasmRefractory CholangiocarcinomaRefractory Malignant Solid Neoplasm
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Early research (Phase 1)Study completedNCT02143401
What this trial is testing

Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
CirrhosisHepatitis B InfectionHepatitis C Infection+6 more
National Cancer Institute (NCI) 29
Early research (Phase 1)Study completedNCT00667641
What this trial is testing

Paclitaxel and Bortezomib in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors

Who this might be right for
Breast CancerColorectal CancerHead and Neck Cancer+6 more
University of Medicine and Dentistry of New Jersey 16
Early research (Phase 1)Study completedNCT01596140
What this trial is testing

Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced Cancer

Who this might be right for
Advanced CancerSolid Tumor
M.D. Anderson Cancer Center 27
Not applicableStudy completedNCT00248547
What this trial is testing

Aprepitant in Preventing Nausea and Vomiting in Patients Who Are Undergoing a Stem Cell Transplant

Who this might be right for
Cancer
OHSU Knight Cancer Institute 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT06390826
What this trial is testing

Testing Sunitinib as Potentially Targeted Treatment in Cancers With cKIT Genetic Changes (MATCH - Subprotocol V)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmRefractory Lymphoma+2 more
National Cancer Institute (NCI) 10
Early research (Phase 1)Study completedNCT00003597
What this trial is testing

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Who this might be right for
Cancer
Children's Oncology Group 16
Testing effectiveness (Phase 2)Ended earlyNCT03610490
What this trial is testing

Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma

Who this might be right for
Malignant Solid NeoplasmMetastatic Colorectal AdenocarcinomaMetastatic Ovarian Carcinoma+9 more
M.D. Anderson Cancer Center 16
Not applicableStudy completedNCT01053494
What this trial is testing

Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated LeukemiaAngioimmunoblastic T-cell Lymphoma+84 more
Wake Forest University Health Sciences 80
Early research (Phase 1)Study completedNCT02923466
What this trial is testing

Ph1 Administration of VSV-IFNβ-NIS Monotherapy and in Combination With Avelumab in Pts With Refractory Solid Tumors

Who this might be right for
Malignant Solid Tumour
Vyriad, Inc. 76
Testing effectiveness (Phase 2)Looking for participantsNCT06265025
What this trial is testing

GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerMalignant MelanomaColorectal Cancer+3 more
GeneMedicine Co., Ltd. 125
Early research (Phase 1)Study completedNCT01017185
What this trial is testing

Study of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial Lesions

Who this might be right for
Refractory Head and Neck CancerSquamous Cell Carcinoma, SkinCarcinoma of the Breast+1 more
Takara Bio Inc. 28
Testing effectiveness (Phase 2)Active Not RecruitingNCT02465060
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmBladder Carcinoma+49 more
National Cancer Institute (NCI) 6,452
Not applicableWithdrawnNCT00900120
What this trial is testing

Collecting and Storing Blood Samples From Patients With Cancer

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
University of Medicine and Dentistry of New Jersey
Early research (Phase 1)Study completedNCT02595866
What this trial is testing

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Who this might be right for
AIDS-Related Non-Hodgkin LymphomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+16 more
National Cancer Institute (NCI) 58
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