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Results for “Refractory Malignant Solid Tumors”

284 trials

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Showing 20 of 284 results

Large-scale testing (Phase 3)Study completedNCT01305200
What this trial is testing

Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant

Who this might be right for
Childhood Acute Lymphoblastic Leukemia in RemissionChildhood Acute Myeloid Leukemia in RemissionChildhood Chronic Myelogenous Leukemia+24 more
Children's Oncology Group 226
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439136
What this trial is testing

Testing Afatinib as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol B)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Testing effectiveness (Phase 2)Study completedNCT00003173
What this trial is testing

High-Dose Thiotepa Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+5 more
Memorial Sloan Kettering Cancer Center 36
Early research (Phase 1)Looking for participantsNCT07189195
What this trial is testing

TR-002 for the Treatment of Advanced Unresectable Metastatic Solid Tumors Unresectable or Metastatic, Refractory Pancreatic Adenocarcinoma

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmMetastatic Pancreatic Adenocarcinoma+5 more
University of California, Davis 52
Early research (Phase 1)Study completedNCT01748721
What this trial is testing

MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma

Who this might be right for
Adult Nasal Type Extranodal NK/T-cell LymphomaAnaplastic Large Cell LymphomaAngioimmunoblastic T-cell Lymphoma+43 more
Morphotek 27
Early research (Phase 1)Ended earlyNCT00101205
What this trial is testing

Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma

Who this might be right for
Angioimmunoblastic T-cell LymphomaB-cell Childhood Acute Lymphoblastic LeukemiaB-cell Chronic Lymphocytic Leukemia+24 more
National Cancer Institute (NCI) 40
Large-scale testing (Phase 3)Study completedNCT00003805
What this trial is testing

Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count

Who this might be right for
Bone Marrow SuppressionFever, Sweats, and Hot FlashesInfection+6 more
European Organisation for Research and Treatment of Cancer - EORTC 859
Testing effectiveness (Phase 2)Study completedNCT00939770
What this trial is testing

Crizotinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

Who this might be right for
Recurrent Childhood Anaplastic Large Cell LymphomaRecurrent Malignant Solid NeoplasmRecurrent Neuroblastoma+3 more
Children's Oncology Group 122
Early research (Phase 1)Study completedNCT00077454
What this trial is testing

Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Previously Treated Childhood RhabdomyosarcomaRecurrent Childhood Brain TumorRecurrent Childhood Cerebellar Astrocytoma+9 more
National Cancer Institute (NCI) 95
Testing effectiveness (Phase 2)Study completedNCT05795595
What this trial is testing

A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors

Who this might be right for
Clear Cell Renal Cell CarcinomaCervical CarcinomaEsophageal Carcinoma+2 more
CRISPR Therapeutics AG 19
Early research (Phase 1)Study completedNCT00667641
What this trial is testing

Paclitaxel and Bortezomib in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors

Who this might be right for
Breast CancerColorectal CancerHead and Neck Cancer+6 more
University of Medicine and Dentistry of New Jersey 16
Early research (Phase 1)Active Not RecruitingNCT03618381
What this trial is testing

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Who this might be right for
Pediatric Solid TumorGerm Cell TumorRetinoblastoma+13 more
Seattle Children's Hospital 44
Testing effectiveness (Phase 2)WithdrawnNCT05660421
What this trial is testing

Itacitinib for the Treatment Steroid Refractory Immune Related Adverse Events Arising From Immune Checkpoint Inhibitors

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid Neoplasm
Douglas Johnson
Early research (Phase 1)Active Not RecruitingNCT04483778
What this trial is testing

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Who this might be right for
Pediatric Solid TumorGerm Cell TumorRetinoblastoma+14 more
Seattle Children's Hospital 68
Testing effectiveness (Phase 2)UnknownNCT03171220
What this trial is testing

Neoantigen Reactive T Cells Combined With SHR-1210 for Chinese Patients With Advanced Refractory Solid Tumors

Who this might be right for
Advanced Malignant Solid Tumor
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07530224
What this trial is testing

JAK Inhibitors for Solid Malignant Tumor Patients With Refractory Immune Checkpoint Inhibitors-related Dermatitis

Who this might be right for
Immune Checkpoint Inhibitor-Induced Dermatitis
Shixiu Wu 35
Testing effectiveness (Phase 2)Study completedNCT03526250
What this trial is testing

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more
National Cancer Institute (NCI) 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT05554380
What this trial is testing

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Treatment Trial

Who this might be right for
Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
National Cancer Institute (NCI) 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT03210714
What this trial is testing

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Childhood Malignant Germ Cell Tumor+29 more
National Cancer Institute (NCI) 20
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