Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Refractory Medulloblastoma”

125 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 125 results

Early research (Phase 1)Study completedNCT00994071
What this trial is testing

A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors

Who this might be right for
MedulloblastomaPontine GliomaEpendymoma+2 more
National Cancer Institute (NCI) 9
Testing effectiveness (Phase 2)Looking for participantsNCT04696029
What this trial is testing

DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma

Who this might be right for
Medulloblastoma
Giselle Sholler 118
Early research (Phase 1)Study completedNCT00063973
What this trial is testing

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+23 more
National Cancer Institute (NCI) 24
Early research (Phase 1)Active Not RecruitingNCT03500991
What this trial is testing

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

Who this might be right for
Central Nervous System Tumor, PediatricGliomaEpendymoma+6 more
Seattle Children's Hospital 10
Early research (Phase 1)Study completedNCT00138216
What this trial is testing

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsUnspecified Childhood Solid Tumor, Protocol Specific
Children's Oncology Group 42
Testing effectiveness (Phase 2)Ended earlyNCT00788125
What this trial is testing

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
City of Hope Medical Center 7
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Large-scale testing (Phase 3)Ended earlyNCT01987596
What this trial is testing

Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer

Who this might be right for
Childhood Choroid Plexus TumorChildhood MedulloblastomaChildhood Pineoblastoma+8 more
Barbara Ann Karmanos Cancer Institute 23
Early research (Phase 1)Study completedNCT00003765
What this trial is testing

O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors

Who this might be right for
Brain and Central Nervous System Tumors
National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Early research (Phase 1)Study completedNCT00077454
What this trial is testing

Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Previously Treated Childhood RhabdomyosarcomaRecurrent Childhood Brain TumorRecurrent Childhood Cerebellar Astrocytoma+9 more
National Cancer Institute (NCI) 95
Early research (Phase 1)Study completedNCT02271711
What this trial is testing

Expanded Natural Killer Cell Infusion in Treating Younger Patients With Recurrent/Refractory Brain Tumors

Who this might be right for
Recurrent Childhood MedulloblastomaRecurrent EpendymomaRecurrent Medulloblastoma
M.D. Anderson Cancer Center 12
Early research (Phase 1)Study completedNCT01158300
What this trial is testing

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 28
Testing effectiveness (Phase 2)Ended earlyNCT01483820
What this trial is testing

Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma

Who this might be right for
NeuroblastomaMedulloblastoma
Giselle Sholler 8
Early research (Phase 1)WithdrawnNCT00458744
What this trial is testing

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Children's Oncology Group
Testing effectiveness (Phase 2)Study completedNCT02095132
What this trial is testing

Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
Central Nervous System Embryonal Tumor With Rhabdoid FeaturesCentral Nervous System Embryonal Tumor, Not Otherwise SpecifiedCentral Nervous System Ganglioneuroblastoma+12 more
National Cancer Institute (NCI) 76
Early research (Phase 1)Study completedNCT00544284
What this trial is testing

Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLymphomaMetastatic Cancer+1 more
City of Hope Medical Center 25
Early research (Phase 1)Study completedNCT00946335
What this trial is testing

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+25 more
National Cancer Institute (NCI) 31
Testing effectiveness (Phase 2)Study completedNCT00939484
What this trial is testing

Vismodegib in Treating Patients With Recurrent or Refractory Medulloblastoma

Who this might be right for
Adult Medulloblastoma
National Cancer Institute (NCI) 31
Testing effectiveness (Phase 2)Study completedNCT00404495
What this trial is testing

Combination of Irinotecan and Temozolomide in Children With Brain Tumors.

Who this might be right for
GliomaMedulloblastoma
Pfizer 83
Load More Results