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Results for “Refractory Medulloblastoma”

123 trials

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Showing 20 of 123 results

Early research (Phase 1)WithdrawnNCT00458744
What this trial is testing

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Children's Oncology Group
Testing effectiveness (Phase 2)Study completedNCT01239316
What this trial is testing

Vismodegib in Treating Younger Patients With Recurrent or Refractory Medulloblastoma

Who this might be right for
Recurrent Childhood Medulloblastoma
National Cancer Institute (NCI) 12
Early research (Phase 1)Ended earlyNCT05429502
What this trial is testing

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Who this might be right for
Neuroblastoma
Novartis Pharmaceuticals 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Not applicableLooking for participantsNCT07242963
What this trial is testing

Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study

Who this might be right for
Medulloblastoma RecurrentMedulloblastoma, Childhood, RecurrentMedulloblastoma, SHH-activated and TP53 Mutant+1 more
Mohammad H. Abu Arja 300
Early research (Phase 1)Study completedNCT00019019
What this trial is testing

Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerKidney Cancer+6 more
National Institutes of Health Clinical Center (CC) 70
Early research (Phase 1)Active Not RecruitingNCT03389802
What this trial is testing

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Who this might be right for
Glioblastoma MultiformeHigh-grade Astrocytoma Not Otherwise Specified (NOS)CNS Primary Tumor, Not Otherwise Specified (NOS)+3 more
Pediatric Brain Tumor Consortium 32
Early research (Phase 1)Ended earlyNCT02255461
What this trial is testing

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Who this might be right for
Childhood Choroid Plexus TumorChildhood EpendymoblastomaChildhood Grade III Meningioma+16 more
Pediatric Brain Tumor Consortium 35
Early research (Phase 1)Study completedNCT00098761
What this trial is testing

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 42
Testing effectiveness (Phase 2)Study completedNCT00004078
What this trial is testing

Irinotecan in Treating Children With Refractory Solid Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+18 more
Children's Oncology Group 181
Testing effectiveness (Phase 2)Ended earlyNCT01483820
What this trial is testing

Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma

Who this might be right for
NeuroblastomaMedulloblastoma
Giselle Sholler 8
Testing effectiveness (Phase 2)Study completedNCT01125800
What this trial is testing

A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB

Who this might be right for
MedulloblastomaRhabdomyosarcomaNeuroblastoma+3 more
Novartis Pharmaceuticals 76
Testing effectiveness (Phase 2)Ended earlyNCT02332889
What this trial is testing

Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs

Who this might be right for
GliomasMedulloblastomaNeuroectodermal Tumors, Primitive
University of Louisville 1
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06485908
What this trial is testing

Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and Ependymoma

Who this might be right for
MedulloblastomaEpendymoma
Assistance Publique Hopitaux De Marseille 40
Large-scale testing (Phase 3)Ended earlyNCT01987596
What this trial is testing

Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer

Who this might be right for
Childhood Choroid Plexus TumorChildhood MedulloblastomaChildhood Pineoblastoma+8 more
Barbara Ann Karmanos Cancer Institute 23
Testing effectiveness (Phase 2)Study completedNCT00066248
What this trial is testing

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Who this might be right for
Brain TumorCentral Nervous System TumorsCachexia+5 more
University of South Florida 70
Testing effectiveness (Phase 2)Study completedNCT00528437
What this trial is testing

Temozolomide,Thiotepa and Carboplatin With Autologous Stem Cell Rescue Followed by 13-cis-retinoic Acid in Patients With Recurrent/Refractory Malignant Brain Tumors

Who this might be right for
Brain Tumors
NYU Langone Health 46
Early research (Phase 1)Looking for participantsNCT07087002
What this trial is testing

GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults

Who this might be right for
MedulloblastomaCentral Nervous System Embryonal TumorRefractory Medulloblastoma+7 more
Stanford University 18
Early research (Phase 1)Study completedNCT00544284
What this trial is testing

Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLymphomaMetastatic Cancer+1 more
City of Hope Medical Center 25
Early research (Phase 1)Active Not RecruitingNCT02359565
What this trial is testing

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeLynch SyndromeMalignant Glioma+8 more
National Cancer Institute (NCI) 71
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