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Results for “Refractory Microsatellite Stable Colorectal Carcinoma”

30 trials

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Showing 20 of 30 results

Testing effectiveness (Phase 2)WithdrawnNCT04119830
What this trial is testing

Rintatolimod and Pembrolizumab for the Treatment of Refractory Metastatic or Unresectable Colorectal Cancer

Who this might be right for
Metastatic Colorectal AdenocarcinomaMicrosatellite StableMismatch Repair Proficient+10 more
Roswell Park Cancer Institute
Testing effectiveness (Phase 2)Active Not RecruitingNCT04599140
What this trial is testing

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal CarcinomaMetastatic Rectal Adenocarcinoma+18 more
M.D. Anderson Cancer Center 51
Early research (Phase 1)Looking for participantsNCT06654037
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

Who this might be right for
Metastatic Microsatellite Stable Colorectal CarcinomaRefractory Microsatellite Stable Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8
National Cancer Institute (NCI) 39
Testing effectiveness (Phase 2)Active Not RecruitingNCT05205330
What this trial is testing

Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers

Who this might be right for
Refractory Metastatic Colorectal CancerSolid TumorMetastatic Microsatellite-stable Colorectal Cancer+3 more
Rottapharm Biotech 107
Testing effectiveness (Phase 2)Study completedNCT03800602
What this trial is testing

Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaRefractory Colorectal Carcinoma+5 more
Emory University 29
Testing effectiveness (Phase 2)WithdrawnNCT03576963
What this trial is testing

Guadecitabine and Nivolumab in Treating Refractory Metastatic Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaCpG Island Methylator PhenotypeMetastatic Microsatellite Stable Colorectal Carcinoma+5 more
University of Southern California
Testing effectiveness (Phase 2)Ended earlyNCT05572684
What this trial is testing

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsMicrosatellite Instability LowMicrosatellite Instability High+9 more
NextCure, Inc. 97
Testing effectiveness (Phase 2)Looking for participantsNCT06589440
What this trial is testing

Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)

Who this might be right for
Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)
Stingray Therapeutics 70
Testing effectiveness (Phase 2)WithdrawnNCT06730100
What this trial is testing

CBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer

Who this might be right for
Metastatic Mismatch Repair Proficient Colorectal CarcinomaRefractory Mismatch Repair Proficient Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8
National Cancer Institute (NCI)
Early research (Phase 1)WithdrawnNCT03802747
What this trial is testing

Immunotherapy Combined With Y-90 and SBRT for Colorectal Liver Metastases

Who this might be right for
Colorectal Cancer
University of Colorado, Denver
Testing effectiveness (Phase 2)Study completedNCT03647839
What this trial is testing

Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Australasian Gastro-Intestinal Trials Group 90
Testing effectiveness (Phase 2)Study completedNCT02860546
What this trial is testing

A Study Evaluating TAS-102 Plus Nivolumab in Patients With MSS CRC

Who this might be right for
Refractory Metastatic Colorectal Cancer
Taiho Oncology, Inc. 18
Testing effectiveness (Phase 2)WithdrawnNCT03182894
What this trial is testing

Epacadostat in Combination With Pembrolizumab and Azacitidine in Subjects With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
James J Lee
Testing effectiveness (Phase 2)WithdrawnNCT05518032
What this trial is testing

Pembrolizumab and Autologous Dendritic Cells for the Treatment of Refractory Colorectal Cancer (CRC)

Who this might be right for
Metastatic Microsatellite Stable Colorectal CarcinomaRecurrent Colorectal CarcinomaStage III Colorectal Cancer AJCC v8+2 more
Roswell Park Cancer Institute
Testing effectiveness (Phase 2)Active Not RecruitingNCT04963283
What this trial is testing

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaColon CancerColon Adenocarcinoma+4 more
University of Colorado, Denver 48
Testing effectiveness (Phase 2)Looking for participantsNCT07147231
What this trial is testing

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

Who this might be right for
Metastatic Colorectal AdenocarcinomaRefractory Colorectal AdenocarcinomaStage III Colorectal Cancer AJCC v8+2 more
National Cancer Institute (NCI) 86
Testing effectiveness (Phase 2)Looking for participantsNCT06522919
What this trial is testing

Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticMicrosatellite Stable Colorectal CarcinomaRefractory Mismatch-repair-proficient (pMMR) Metastatic Colorectal Cancer
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Not applicableStudy completedNCT05942768
What this trial is testing

Anti-PD-1 Antibody Plus Regorafenib in Refractory Microsatellite Stable Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Adenocarcinoma
Hunan Cancer Hospital 103
Testing effectiveness (Phase 2)Study completedNCT04332653
What this trial is testing

NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

Who this might be right for
Any Advanced Solid TumorsTriple Negative Breast CancerNon Small Cell Lung Cancer+4 more
NeoImmuneTech 215
Testing effectiveness (Phase 2)Study completedNCT03711058
What this trial is testing

Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer

Who this might be right for
Unresectable or Metastatic Microsatellite Stable (MSS) Solid TumorMicrosatellite Stable (MSS) Colon Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 48
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