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Results for “Refractory Multiple Sclerosis”

51 trials

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Showing 20 of 51 results

Very early researchNot Yet RecruitingNCT07583030
What this trial is testing

A Clinical Study to Evaluate LVIVO-TaVec400 for the Treatment of Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE)Relapsed/Refractory IgG4-Related Disease (r/r IgG4-RD)Progressive Multiple Sclerosis (PMS)+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 44
Not applicableStudy completedNCT04687332
What this trial is testing

IA or PE - What is the Best Treatment Option of Steroid Refractory Neurological Autoimmune Diseases

Who this might be right for
Neurological Autoimmune Diseases
University Medical Center Mainz 32
Testing effectiveness (Phase 2)WithdrawnNCT00296205
What this trial is testing

Phase II High-Dose Cyclophosphamide for Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Stony Brook University 25
Early research (Phase 1)Looking for participantsNCT07224373
What this trial is testing

An Open-label Study of AZD0120 in Adults With Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
AstraZeneca 24
Testing effectiveness (Phase 2)Looking for participantsNCT06794008
What this trial is testing

BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusInflammatory MyopathySystemic Sclerosis (SSc)+6 more
Peking University People's Hospital 50
Not applicableNot Yet RecruitingNCT06228781
What this trial is testing

Autologous Hematopoietic Stem Cell Transplantation for Refractory Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
Tianjin Medical University General Hospital 20
Early research (Phase 1)Not Yet RecruitingNCT07341828
What this trial is testing

C-CAR168 in the Treatment of Central Nervous System Autoimmune Diseases Refractory to Standard Therapy

Who this might be right for
Multiple Sclerosis (MS)Neuromyelitis Optica Spectrum Disorders (NMOSD)Autoimmune Encephalitis+1 more
Huashan Hospital 15
Not applicableEnded earlyNCT03886753
What this trial is testing

Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products

Who this might be right for
ALSAutism Spectrum DisorderCancer+15 more
Children's Hospital of Philadelphia 10
Very early researchNot Yet RecruitingNCT07674147
What this trial is testing

RD06-05 Universal CD19/BCMA CAR-T for Refractory Pediatric Autoimmune Diseases

Who this might be right for
Autoimmune DiseasesSLE - Systemic Lupus ErythematosusSSc-Systemic Sclerosis+3 more
The Children's Hospital of Zhejiang University School of Medicine 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07804004
What this trial is testing

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Refractory Neurologic Autoimmune Disease

Who this might be right for
Progressive Multiple Sclerosis (PMS)Neuromyelitis OpticaMyelin Oligodendrocyte Glycoprotein Antibody-associated Disease+2 more
CRISPR Therapeutics 220
Early research (Phase 1)UnknownNCT01624714
What this trial is testing

Study of Alemtuzumab in Treatment Refractory MS Subjects/Alemtuzumab Naive & Alemtuzumab Experienced Subjects

Who this might be right for
Multiple Sclerosis
Samuel Forrester Hunter, MD, PhD 60
Early research (Phase 1)Active Not RecruitingNCT06451159
What this trial is testing

KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis

Who this might be right for
Progressive Multiple Sclerosis
Bruce Cree 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07825389
What this trial is testing

C-CAR168 in Participants With Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
AbelZeta Inc. 119
Testing effectiveness (Phase 2)Active Not RecruitingNCT06384976
What this trial is testing

KYSA-7: A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Primary ProgressiveMultiple Sclerosis, Secondary ProgressiveMultiple Sclerosis+1 more
Kyverna Therapeutics 120
Testing effectiveness (Phase 2)Ended earlyNCT00112723
What this trial is testing

Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

Who this might be right for
Adult Lymphocyte Depletion Hodgkin LymphomaAdult Lymphocyte Predominant Hodgkin LymphomaAdult Mixed Cellularity Hodgkin Lymphoma+25 more
National Cancer Institute (NCI) 46
Early research (Phase 1)Looking for participantsNCT07587125
What this trial is testing

Safety and Efficacy of S103 Cells in Progressive/Refractory Multiple Sclerosis

Who this might be right for
Multiple Sclerosis (MS) Primary ProgressiveMultiple SclerosisMultiple Sclerosis (MS) Secondary Progressive+1 more
Xijing Hospital 9
Very early researchNot Yet RecruitingNCT07748637
What this trial is testing

A Clinical Study to Evaluate the Safety and Efficacy of GT802 Injection in the Treatment of Relapsing/Refractory Multiple Sclerosis

Who this might be right for
Multiple Sclerosis (MS)
Daishi Tian 12
Very early researchLooking for participantsNCT06939166
What this trial is testing

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/B Cell Maturation Antigen （CD19/BCMA） in Patients With r/r Neurological Autoimmune Diseases

Who this might be right for
Neuromyelitis Optica Spectrum DisordersMyasthenia GravisMultiple Sclerosis+2 more
Tianjin Huanhu Hospital 12
Large-scale testing (Phase 3)Looking for participantsNCT07403266
What this trial is testing

Treatment With Full-spectrum Cannabis Extract of Refractory Epilepsy Associated With Tuberous Sclerosis Complex (TSC)

Who this might be right for
Tuberous Sclerosis Complex (TSC)
Oils4Cure 84
Large-scale testing (Phase 3)Study completedNCT01606176
What this trial is testing

Evaluate the Effects of Cannabis Based Medicine in Patients With Pain of Neurological Origin

Who this might be right for
PainMultiple Sclerosis
Jazz Pharmaceuticals 70
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