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Results for “Refractory Pediatric Solid Tumor”

229 trials

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Showing 20 of 229 results

Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Testing effectiveness (Phase 2)Study completedNCT04238819
What this trial is testing

Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Who this might be right for
Relapsed Solid TumorRefractory Solid Tumor
Eli Lilly and Company 47
Testing effectiveness (Phase 2)Study completedNCT03233204
What this trial is testing

Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+33 more
National Cancer Institute (NCI) 6
Testing effectiveness (Phase 2)Study completedNCT01614795
What this trial is testing

Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma

Who this might be right for
Childhood Alveolar Soft Part SarcomaChildhood AngiosarcomaChildhood Epithelioid Sarcoma+12 more
National Cancer Institute (NCI) 46
Testing effectiveness (Phase 2)UnknownNCT00084695
What this trial is testing

Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases

Who this might be right for
Childhood Langerhans Cell HistiocytosisFanconi AnemiaLeukemia+5 more
Milton S. Hershey Medical Center 25
Early research (Phase 1)Study completedNCT00217412
What this trial is testing

Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia

Who this might be right for
Childhood Acute Promyelocytic Leukemia (M3)Childhood Atypical Teratoid/Rhabdoid TumorChildhood Burkitt Lymphoma+16 more
National Cancer Institute (NCI) 60
Early research (Phase 1)Looking for participantsNCT05608148
What this trial is testing

Clinical Trial of GAIA-102 for Refractory/Relapse Neuroblastomas and Other Malignant Pediatric Solid Tumors

Who this might be right for
Refractory/Relapse NeuroblastomaPediatric Solid Tumors
Kyushu University 61
Testing effectiveness (Phase 2)Study completedNCT00005811
What this trial is testing

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

Who this might be right for
AIDS-related Diffuse Large Cell LymphomaAIDS-related Diffuse Mixed Cell LymphomaAIDS-related Diffuse Small Cleaved Cell Lymphoma+17 more
National Cancer Institute (NCI) 77
Post-approval studies (Phase 4)Study completedNCT00230217
What this trial is testing

Study of Rasburicase as Treatment or Prevention of Hyperuricemia Associated With Tumor Lysis Syndrome in Patients With Relapsed or Refractory Lymphoma, Leukemia, or Solid Tumor Malignancy

Who this might be right for
TumorsHyperuricemiaTumor Lysis Syndrome
Sanofi 94
Early research (Phase 1)UnknownNCT02013336
What this trial is testing

Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors

Who this might be right for
Recurrent or Refractory Solid TumorsEwing SarcomaRhabdomyosarcoma+2 more
South Plains Oncology Consortium 30
Testing effectiveness (Phase 2)Looking for participantsNCT03934372
What this trial is testing

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

Who this might be right for
Acute Myeloid LeukemiaAccelerated Phase Chronic Myeloid LeukemiaBlast Phase Chronic Myeloid Leukemia+6 more
Incyte Biosciences International Sàrl 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT02574728
What this trial is testing

Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors

Who this might be right for
Cancer
Emory University 46
Testing effectiveness (Phase 2)Study completedNCT01445080
What this trial is testing

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

Who this might be right for
Blastic PhaseChildhood Acute Promyelocytic Leukemia With PML-RARAChildhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive+7 more
National Cancer Institute (NCI) 70
Early research (Phase 1)Ended earlyNCT04239040
What this trial is testing

GVAX Plus Checkpoint Blockade in Neuroblastoma

Who this might be right for
NeuroblastomaPediatric Solid Tumor
Dana-Farber Cancer Institute 19
Testing effectiveness (Phase 2)Looking for participantsNCT06721689
What this trial is testing

PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors

Who this might be right for
Refractory Solid TumorsRelapsed Solid TumorsRelapsed Neuroblastoma+3 more
Theodore Laetsch 59
Early research (Phase 1)Study completedNCT00107458
What this trial is testing

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

Who this might be right for
Brain and Central Nervous System TumorsUnspecified Childhood Solid Tumor, Protocol Specific
Children's Oncology Group 26
Early research (Phase 1)Ended earlyNCT00003194
What this trial is testing

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors

Who this might be right for
Unspecified Childhood Solid Tumor, Protocol Specific
Seattle Children's Hospital 24
Early research (Phase 1)Looking for participantsNCT05857969
What this trial is testing

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

Who this might be right for
Recurrent Childhood Acute Myeloid LeukemiaRecurrent Childhood Acute Lymphoblastic LeukemiaRecurrent Childhood Large Cell Lymphoma+15 more
Florida International University 65
Testing effectiveness (Phase 2)Active Not RecruitingNCT03698994
What this trial is testing

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Ependymal TumorRecurrent Ewing Sarcoma+33 more
National Cancer Institute (NCI) 20
Early research (Phase 1)Study completedNCT02793466
What this trial is testing

Durvalumab in Pediatric and Adolescent Patients

Who this might be right for
Solid TumorLymphomaCentral Nervous System Tumors
Leo Mascarenhas 15
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