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Results for “Refractory Pediatric Solid Tumors”

160 trials

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Showing 20 of 160 results

Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Testing effectiveness (Phase 2)Looking for participantsNCT03934372
What this trial is testing

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

Who this might be right for
Acute Myeloid LeukemiaAccelerated Phase Chronic Myeloid LeukemiaBlast Phase Chronic Myeloid Leukemia+6 more
Incyte Biosciences International Sàrl 70
Early research (Phase 1)Study completedNCT00011414
What this trial is testing

Phase I Trial of Tariquidar (XR9576) in Combination With Doxorubicin, Vinorelbine, or Docetaxel in Pediatric Patients With Solid Tumors

Who this might be right for
Wilms' TumorSarcomaAdenaocortical Carcinoma+2 more
National Cancer Institute (NCI) 29
Early research (Phase 1)Looking for participantsNCT05521984
What this trial is testing

Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

Who this might be right for
Pediatric Brain TumorPediatric Solid Tumor
Washington University School of Medicine 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Testing effectiveness (Phase 2)Ended earlyNCT03690869
What this trial is testing

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Who this might be right for
Relapsed Solid TumorRefractory Solid TumorRelapsed Central Nervous System Tumor+3 more
Regeneron Pharmaceuticals 57
Testing effectiveness (Phase 2)Looking for participantsNCT05734066
What this trial is testing

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

Who this might be right for
Refractory Ewing SarcomaRelapsed Ewing SarcomaEwing Sarcoma
Jazz Pharmaceuticals 60
Early research (Phase 1)Study completedNCT00101270
What this trial is testing

Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Diffuse Large Cell Lymphoma+26 more
National Cancer Institute (NCI) 24
Early research (Phase 1)Study completedNCT00363272
What this trial is testing

Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Study completedNCT02303028
What this trial is testing

Phase I Dose Escalation Study of Topotecan and Pazopanib in Children With Recurrent/Refractory Solid Tumours

Who this might be right for
Solid Tumors
The Hospital for Sick Children 30
Early research (Phase 1)Active Not RecruitingNCT03420963
What this trial is testing

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Who this might be right for
Recurrent Cutaneous MelanomaRecurrent Lip and Oral Cavity CarcinomaRecurrent Malignant Endocrine Neoplasm+25 more
M.D. Anderson Cancer Center 12
Early research (Phase 1)Looking for participantsNCT02379416
What this trial is testing

Combination Nilotinib and Paclitaxel in Adults With Relapsed Solid Tumors

Who this might be right for
Solid Tumors
National Cancer Institute (NCI) 70
Early research (Phase 1)Study completedNCT00004212
What this trial is testing

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsLymphomaUnspecified Childhood Solid Tumor, Protocol Specific
Daiichi Sankyo
Testing effectiveness (Phase 2)Study completedNCT00106353
What this trial is testing

Study Evaluating Biomarkers In Relapsed/Refractory Pediatric Solid Tumors

Who this might be right for
AdenocarcinomaNeoplasms
Pfizer 71
Testing effectiveness (Phase 2)Study completedNCT03526250
What this trial is testing

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more
National Cancer Institute (NCI) 23
Early research (Phase 1)Active Not RecruitingNCT03478462
What this trial is testing

Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma

Who this might be right for
Pediatric Solid TumorPediatric LymphomaPediatric Brain Tumor+5 more
Cellectar Biosciences, Inc. 30
Early research (Phase 1)Study completedNCT02982941
What this trial is testing

Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors

Who this might be right for
NeuroblastomaRhabdomyosarcomaOsteosarcoma+3 more
MacroGenics 25
Early research (Phase 1)Active Not RecruitingNCT03618381
What this trial is testing

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Who this might be right for
Pediatric Solid TumorGerm Cell TumorRetinoblastoma+13 more
Seattle Children's Hospital 44
Early research (Phase 1)Study completedNCT00187174
What this trial is testing

Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumors

Who this might be right for
TumorsBrain TumorsRhabdomyosarcoma+1 more
St. Jude Children's Research Hospital 41
Early research (Phase 1)Ended earlyNCT03451825
What this trial is testing

Phase I/II Study of Avelumab in Pediatric Cancer Participants

Who this might be right for
Refractory or Relapsed Solid TumorsLymphoma
EMD Serono Research & Development Institute, Inc. 21
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