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Results for “Refractory Primary Central Nervous System Neoplasm”

138 trials

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Showing 20 of 138 results

Testing effectiveness (Phase 2)Looking for participantsNCT05681195
What this trial is testing

Zanubrutinib With Pemetrexed to Treat Relapsed/Refractory Primary and Secondary Central Nervous System (CNS) Lymphomas

Who this might be right for
Primary Central Nervous System LymphomaSecondary Central Nervous System LymphomaRelapsed Cancer+1 more
Baptist Health South Florida 15
Early research (Phase 1)Looking for participantsNCT05131022
What this trial is testing

NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)Diffuse Large B Cell Lymphoma (DLBCL)+6 more
Nurix Therapeutics, Inc. 572
Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Testing effectiveness (Phase 2)Active Not RecruitingNCT02867592
What this trial is testing

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Who this might be right for
Adrenal Cortical CarcinomaAlveolar Soft Part SarcomaCentral Nervous System Neoplasm+41 more
National Cancer Institute (NCI) 109
Early research (Phase 1)Looking for participantsNCT04807881
What this trial is testing

Phase Ib Clinical Study of Keynatinib

Who this might be right for
Lymphoma, B-Cell
Medolution Ltd. 75
Early research (Phase 1)Study completedNCT00005021
What this trial is testing

Combination Chemotherapy With or Without Biological Therapy in Treating Patients With Refractory Solid Tumor or Lymphoma

Who this might be right for
LymphomaSmall Intestine CancerUnspecified Adult Solid Tumor, Protocol Specific
Fox Chase Cancer Center 17
Early research (Phase 1)Study completedNCT01588015
What this trial is testing

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+123 more
City of Hope Medical Center 36
Early research (Phase 1)Study completedNCT00063973
What this trial is testing

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+23 more
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Ended earlyNCT00788125
What this trial is testing

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
City of Hope Medical Center 7
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Testing effectiveness (Phase 2)Ended earlyNCT00210366
What this trial is testing

Salvage Therapy With Idarubicin in Relapsing CNS Lymphoma

Who this might be right for
Lymphoma, B-Cell
International Extranodal Lymphoma Study Group (IELSG) 25
Very early researchStudy completedNCT00424242
What this trial is testing

Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Northwestern University 15
Testing effectiveness (Phase 2)Looking for participantsNCT05278208
What this trial is testing

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

Who this might be right for
High Grade GliomaMeningiomaEmbryonal Tumor+10 more
Nationwide Children's Hospital 65
Testing effectiveness (Phase 2)Looking for participantsNCT07523737
What this trial is testing

Pomalidomide, Anti-PD-1 Antibody Combined With Selinexor (PPS) in Relapsed/Refractory Primary Central Nervous System Diffuse Large B-Cell Lymphoma

Who this might be right for
Primary Central Nervous System Lymphoma (PCNSL)Diffuse Large B Cell Lymphoma (DLBCL)
Beijing Tongren Hospital 43
Early research (Phase 1)Study completedNCT01158300
What this trial is testing

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 28
Testing effectiveness (Phase 2)Study completedNCT02095132
What this trial is testing

Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
Central Nervous System Embryonal Tumor With Rhabdoid FeaturesCentral Nervous System Embryonal Tumor, Not Otherwise SpecifiedCentral Nervous System Ganglioneuroblastoma+12 more
National Cancer Institute (NCI) 76
Testing effectiveness (Phase 2)Study completedNCT00006225
What this trial is testing

Peripheral Stem Cell Transplantation in Treating Patients With Breast Cancer or Hematologic Cancer

Who this might be right for
Breast CancerLeukemiaLymphoma+2 more
Northwestern University
Early research (Phase 1)Study completedNCT00544284
What this trial is testing

Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLymphomaMetastatic Cancer+1 more
City of Hope Medical Center 25
Early research (Phase 1)Study completedNCT00005639
What this trial is testing

Azacitidine Plus Phenylbutyrate in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous Treatment

Who this might be right for
LymphomaSmall Intestine CancerUnspecified Adult Solid Tumor, Protocol Specific
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 34
Not applicableEnded earlyNCT00899951
What this trial is testing

Studying Fentanyl in Patients With Cancer

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 2
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