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Results for “Refractory Rhabdoid Tumor”

61 trials

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Showing 20 of 61 results

Early research (Phase 1)Ended earlyNCT05429502
What this trial is testing

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Who this might be right for
Neuroblastoma
Novartis Pharmaceuticals 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT04416568
What this trial is testing

Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

Who this might be right for
Malignant Rhabdoid TumorRhabdoid Tumor of the KidneyEpithelioid Sarcoma+4 more
Dana-Farber Cancer Institute 45
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Early research (Phase 1)Study completedNCT01625351
What this trial is testing

CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

Who this might be right for
Ewing SarcomaGastrointestinal TumorGerm Cell Tumor+10 more
St. Jude Children's Research Hospital 23
Testing effectiveness (Phase 2)Looking for participantsNCT04901702
What this trial is testing

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Who this might be right for
Recurrent Solid TumorRecurrent Ewing SarcomaRecurrent Hepatoblastoma+19 more
St. Jude Children's Research Hospital 90
Early research (Phase 1)Looking for participantsNCT07087002
What this trial is testing

GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults

Who this might be right for
MedulloblastomaCentral Nervous System Embryonal TumorRefractory Medulloblastoma+7 more
Stanford University 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213704
What this trial is testing

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor+30 more
National Cancer Institute (NCI) 9
Early research (Phase 1)Study completedNCT00138216
What this trial is testing

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsUnspecified Childhood Solid Tumor, Protocol Specific
Children's Oncology Group 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT04284774
What this trial is testing

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Malignant Solid NeoplasmRecurrent Adrenal Gland PheochromocytomaRecurrent Ectomesenchymoma+38 more
National Cancer Institute (NCI) 5
Early research (Phase 1)Study completedNCT00015899
What this trial is testing

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 53
Early research (Phase 1)Study completedNCT02601937
What this trial is testing

EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma

Who this might be right for
Rhabdoid TumorsINI1-negative TumorsSynovial Sarcoma+1 more
Epizyme, Inc. 109
Early research (Phase 1)Study completedNCT00946335
What this trial is testing

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+25 more
National Cancer Institute (NCI) 31
Testing effectiveness (Phase 2)Study completedNCT03213678
What this trial is testing

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+30 more
National Cancer Institute (NCI) 18
Early research (Phase 1)Ended earlyNCT01088763
What this trial is testing

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System ChoriocarcinomaChildhood Central Nervous System Germinoma+43 more
National Cancer Institute (NCI) 129
Early research (Phase 1)Active Not RecruitingNCT03500991
What this trial is testing

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

Who this might be right for
Central Nervous System Tumor, PediatricGliomaEpendymoma+6 more
Seattle Children's Hospital 10
Testing effectiveness (Phase 2)Study completedNCT02601950
What this trial is testing

Tazemetostat in Adult Participants With Soft Tissue Sarcoma

Who this might be right for
Malignant Rhabdoid Tumors (MRT)Rhabdoid Tumors of the Kidney (RTK)Atypical Teratoid Rhabdoid Tumors (ATRT)+8 more
Epizyme, Inc. 267
Early research (Phase 1)Looking for participantsNCT03911388
What this trial is testing

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Who this might be right for
Neoplasms, BrainGlioblastoma MultiformeGlioblastoma of Cerebellum+30 more
M.D. Anderson Cancer Center 24
Early research (Phase 1)Study completedNCT00100880
What this trial is testing

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+23 more
National Cancer Institute (NCI) 45
Early research (Phase 1)Study completedNCT00326664
What this trial is testing

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Cerebral Anaplastic Astrocytoma+18 more
National Cancer Institute (NCI) 55
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