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Results for “Refractory Solid Tumors in Children”

156 trials

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Showing 20 of 156 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02867592
What this trial is testing

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Who this might be right for
Adrenal Cortical CarcinomaAlveolar Soft Part SarcomaCentral Nervous System Neoplasm+41 more
National Cancer Institute (NCI) 109
Early research (Phase 1)Study completedNCT00993044
What this trial is testing

Vincristine, Escalating Doses of Irinotecan, Temozolomide and Bevacizumab (Vit-b) in Pediatric and Adolescent Patients With Recurrent or Refractory Solid Tumors of Non-hematopoietic Origin

Who this might be right for
Refractory Solid Tumors in Children
Children's Hospital Los Angeles 13
Early research (Phase 1)Study completedNCT01259479
What this trial is testing

Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors

Who this might be right for
Solid TumorsBrain TumorsBrain Metastases
National Cancer Institute (NCI) 9
Early research (Phase 1)Study completedNCT00039481
What this trial is testing

Oblimersen Plus Combination Chemotherapy and Dexrazoxane in Treating Children and Adolescents With Relapsed or Refractory Solid Tumors

Who this might be right for
Cardiac ToxicityUnspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 15
Testing effectiveness (Phase 2)Ended earlyNCT01610570
What this trial is testing

Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcoma

Who this might be right for
Ewing SarcomaSarcoma
National Cancer Institute (NCI) 8
Early research (Phase 1)Study completedNCT00138216
What this trial is testing

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsUnspecified Childhood Solid Tumor, Protocol Specific
Children's Oncology Group 42
Testing effectiveness (Phase 2)Study completedNCT01154816
What this trial is testing

Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
HepatoblastomaPreviously Treated Childhood RhabdomyosarcomaRecurrent Childhood Acute Lymphoblastic Leukemia+8 more
Children's Oncology Group 118
Early research (Phase 1)Ended earlyNCT00933985
What this trial is testing

Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia

Who this might be right for
Acute Leukemias of Ambiguous LineageAcute Undifferentiated LeukemiaAngioimmunoblastic T-cell Lymphoma+26 more
National Cancer Institute (NCI) 22
Early research (Phase 1)Study completedNCT02085148
What this trial is testing

A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy

Who this might be right for
Pediatric Oncology
Bayer 62
Early research (Phase 1)Study completedNCT00316953
What this trial is testing

Dasatinib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Did Not Respond to Imatinib Mesylate

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaBlastic Phase Chronic Myelogenous LeukemiaChildhood Chronic Myelogenous Leukemia+5 more
National Cancer Institute (NCI) 48
Early research (Phase 1)Study completedNCT02677116
What this trial is testing

Olaratumab Alone and in Combination With Standard Chemotherapies in Children With Cancer

Who this might be right for
Neoplasm Metastasis
Eli Lilly and Company 68
Not applicableWithdrawnNCT00402935
What this trial is testing

Ovarian Damage in Young Premenopausal Women Undergoing Chemotherapy for Cancer

Who this might be right for
LeukemiaLong-term Effects Secondary to Cancer Therapy in AdultsLong-term Effects Secondary to Cancer Therapy in Children+5 more
Case Comprehensive Cancer Center
Early research (Phase 1)Study completedNCT02982941
What this trial is testing

Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors

Who this might be right for
NeuroblastomaRhabdomyosarcomaOsteosarcoma+3 more
MacroGenics 25
Large-scale testing (Phase 3)Ended earlyNCT01987596
What this trial is testing

Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer

Who this might be right for
Childhood Choroid Plexus TumorChildhood MedulloblastomaChildhood Pineoblastoma+8 more
Barbara Ann Karmanos Cancer Institute 23
Early research (Phase 1)Study completedNCT00756340
What this trial is testing

A Trial of Everolimus and Bevacizumab in Children With Recurrent Solid Tumors

Who this might be right for
Recurrent or Refractory Solid TumorsCNS Malignancies
St. Jude Children's Research Hospital 16
Testing effectiveness (Phase 2)Study completedNCT02372006
What this trial is testing

Trial of Afatinib in Pediatric Tumours

Who this might be right for
Neuroectodermal TumorsRhabdomyosarcoma
Boehringer Ingelheim 56
Testing effectiveness (Phase 2)Looking for participantsNCT06208657
What this trial is testing

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

Who this might be right for
Childhood CancerChildhood Solid TumorChildhood Brain Tumor+2 more
Australian & New Zealand Children's Haematology/Oncology Group 90
Testing effectiveness (Phase 2)Looking for participantsNCT06541262
What this trial is testing

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

Who this might be right for
NeuroblastomaEwing SarcomaOsteosarcoma+2 more
Milton S. Hershey Medical Center 104
Testing effectiveness (Phase 2)Study completedNCT00057473
What this trial is testing

A Phase II Study of Carboplatin Plus Irinotecan Versus Irinotecan in Children With Refractory Solid Tumors

Who this might be right for
Neoplasms
Bristol-Myers Squibb
Testing effectiveness (Phase 2)Study completedNCT04773782
What this trial is testing

Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling

Who this might be right for
Solid Tumor, Unspecified, ChildRelapsed Solid NeoplasmCNS Tumor
Blueprint Medicines Corporation 29
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