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Results for “Refractory Solid Tumors in Children”

156 trials

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Showing 20 of 156 results

Early research (Phase 1)WithdrawnNCT04500548
What this trial is testing

Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeHematopoietic and Lymphoid Cell NeoplasmLynch Syndrome+9 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT00756340
What this trial is testing

A Trial of Everolimus and Bevacizumab in Children With Recurrent Solid Tumors

Who this might be right for
Recurrent or Refractory Solid TumorsCNS Malignancies
St. Jude Children's Research Hospital 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Early research (Phase 1)Looking for participantsNCT06612645
What this trial is testing

Safety and Efficacy of CMD03 CAR T Cell in Children With Relapse or Refractory Solid Tumors

Who this might be right for
Pediatric CancersSolid Tumor Pediatric
Chulalongkorn University 9
Early research (Phase 1)Active Not RecruitingNCT04483778
What this trial is testing

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Who this might be right for
Pediatric Solid TumorGerm Cell TumorRetinoblastoma+14 more
Seattle Children's Hospital 68
Early research (Phase 1)UnknownNCT04213612
What this trial is testing

DCV in the Treatment of Recurrence and Refractory Childhood Solid Tumors

Who this might be right for
Unrecognized Condition
Sun Yat-sen University 21
Early research (Phase 1)Study completedNCT00003370
What this trial is testing

Irofulven in Treating Children With Recurrent or Refractory Solid Tumors

Who this might be right for
Unspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 12
Early research (Phase 1)Study completedNCT00993044
What this trial is testing

Vincristine, Escalating Doses of Irinotecan, Temozolomide and Bevacizumab (Vit-b) in Pediatric and Adolescent Patients With Recurrent or Refractory Solid Tumors of Non-hematopoietic Origin

Who this might be right for
Refractory Solid Tumors in Children
Children's Hospital Los Angeles 13
Early research (Phase 1)Study completedNCT00004212
What this trial is testing

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsLymphomaUnspecified Childhood Solid Tumor, Protocol Specific
Daiichi Sankyo
Testing effectiveness (Phase 2)Study completedNCT00628732
What this trial is testing

A Pharmacokinetic Study of Oral Cyclophosphamide and Topotecan in Children With Recurrent Solid Tumors

Who this might be right for
Solid Tumors
Children's Medical Center Dallas 36
Testing effectiveness (Phase 2)Study completedNCT02304458
What this trial is testing

Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

Who this might be right for
Metastatic MelanomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorRecurrent Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 140
Early research (Phase 1)Study completedNCT00021216
What this trial is testing

Bortezomib in Treating Children With Advanced Solid Tumors

Who this might be right for
Unspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 36
Early research (Phase 1)Study completedNCT00016861
What this trial is testing

Irinotecan in Treating Children With Refractory or Progressive Solid Tumors

Who this might be right for
Unspecified Childhood Solid Tumor, Protocol Specific
Texas Children's Cancer Center
Early research (Phase 1)Study completedNCT01141244
What this trial is testing

Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
Unspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 72
Testing effectiveness (Phase 2)Study completedNCT00030667
What this trial is testing

Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood

Who this might be right for
Childhood Desmoplastic Small Round Cell TumorChildhood Synovial SarcomaGastrointestinal Stromal Tumor+5 more
National Cancer Institute (NCI) 100
Early research (Phase 1)Study completedNCT00012181
What this trial is testing

Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas

Who this might be right for
Recurrent Childhood Brain Stem GliomaRecurrent Childhood Cerebellar AstrocytomaRecurrent Childhood Cerebral Astrocytoma+19 more
National Cancer Institute (NCI) 30
Early research (Phase 1)WithdrawnNCT00458744
What this trial is testing

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Children's Oncology Group
Testing effectiveness (Phase 2)Looking for participantsNCT06607692
What this trial is testing

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

Who this might be right for
Solid Tumor CancerMedulloblastomaHigh Risk Neuroblastoma+17 more
Fundación de investigación HM 25
Early research (Phase 1)Study completedNCT02164838
What this trial is testing

VEGF Receptor Tyrosine Kinase Inhibitor Axitinib in Children With Recurrent or Refractory Solid Tumors

Who this might be right for
Refractory or Recurrent Solid Tumors, Excluding CNS Tumors
Children's Oncology Group 51
Testing effectiveness (Phase 2)Ended earlyNCT04730349
What this trial is testing

Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer

Who this might be right for
EpendymomaEwing SarcomaHigh-grade Glioma+7 more
Bristol-Myers Squibb 15
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