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Results for “Refractory Solid Tumors in Children”

157 trials

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Showing 20 of 157 results

Testing effectiveness (Phase 2)WithdrawnNCT02011126
What this trial is testing

Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
HepatoblastomaPreviously Treated Childhood RhabdomyosarcomaRecurrent Childhood Liver Cancer+5 more
Children's Oncology Group
Not applicableAvailableNCT06872489
What this trial is testing

Expanded Access Protocol for the Use of SL-28 in the Treatment of Advanced Solid Tumors

Who this might be right for
Neuroblastoma in ChildrenNeuroblastoma, Recurrent, RefractoryAdvanced Cancer+7 more
Second Life Therapeutics
Early research (Phase 1)Study completedNCT01222780
What this trial is testing

To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer

Who this might be right for
SarcomaNeuroblastomaWilms Tumor+3 more
Acrotech Biopharma Inc. 22
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Early research (Phase 1)Study completedNCT00039481
What this trial is testing

Oblimersen Plus Combination Chemotherapy and Dexrazoxane in Treating Children and Adolescents With Relapsed or Refractory Solid Tumors

Who this might be right for
Cardiac ToxicityUnspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 15
Testing effectiveness (Phase 2)Looking for participantsNCT06607692
What this trial is testing

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).

Who this might be right for
Solid Tumor CancerMedulloblastomaHigh Risk Neuroblastoma+19 more
Fundación de investigación HM 25
Early research (Phase 1)Active Not RecruitingNCT03478462
What this trial is testing

Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas

Who this might be right for
Pediatric Solid TumorPediatric LymphomaPediatric Brain Tumor+5 more
Cellectar Biosciences, Inc. 30
Early research (Phase 1)Study completedNCT00003288
What this trial is testing

Tirapazamine Plus Cyclophosphamide in Treating Children With Refractory Solid Tumors

Who this might be right for
Unspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 12
Early research (Phase 1)Study completedNCT02793466
What this trial is testing

Durvalumab in Pediatric and Adolescent Patients

Who this might be right for
Solid TumorLymphomaCentral Nervous System Tumors
Leo Mascarenhas 15
Early research (Phase 1)Study completedNCT00040781
What this trial is testing

Gefitinib in Treating Children With Refractory Solid Tumors

Who this might be right for
Unspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI) 45
Testing effectiveness (Phase 2)Study completedNCT04238819
What this trial is testing

Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Who this might be right for
Relapsed Solid TumorRefractory Solid Tumor
Eli Lilly and Company 47
Testing effectiveness (Phase 2)Study completedNCT03320330
What this trial is testing

Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors

Who this might be right for
Recurrent Malignant Solid NeoplasmRecurrent OsteosarcomaRefractory Malignant Solid Neoplasm+1 more
Children's Oncology Group 26
Early research (Phase 1)Study completedNCT01528046
What this trial is testing

Metformin in Children With Relapsed or Refractory Solid Tumors

Who this might be right for
Solid TumorsPrimary Brain Tumors
H. Lee Moffitt Cancer Center and Research Institute 26
Early research (Phase 1)Looking for participantsNCT06006273
What this trial is testing

A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors

Who this might be right for
Refractory Solid Tumors
M.D. Anderson Cancer Center 48
Testing effectiveness (Phase 2)Study completedNCT00003745
What this trial is testing

Chemotherapy in Treating Children With Recurrent or Refractory Sarcomas

Who this might be right for
Sarcoma
National Cancer Institute (NCI) 125
Testing effectiveness (Phase 2)Looking for participantsNCT07502287
What this trial is testing

Dual-Target GD2/B7-H3 CAR-NK Cells for Pediatric Relapsed or Refractory Neuroblastoma

Who this might be right for
Relapsed NeuroblastomaRefractory NeuroblastomaHigh-Risk Neuroblastoma+1 more
Beijing Biotech 36
Testing effectiveness (Phase 2)Study completedNCT02304458
What this trial is testing

Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

Who this might be right for
Metastatic MelanomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorRecurrent Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 140
Early research (Phase 1)Active Not RecruitingNCT04483778
What this trial is testing

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Who this might be right for
Pediatric Solid TumorGerm Cell TumorRetinoblastoma+14 more
Seattle Children's Hospital 68
Early research (Phase 1)Study completedNCT01132911
What this trial is testing

A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas

Who this might be right for
LymphomaSarcomaWilmsTumor+1 more
National Cancer Institute (NCI) 5
Early research (Phase 1)Study completedNCT00012181
What this trial is testing

Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas

Who this might be right for
Recurrent Childhood Brain Stem GliomaRecurrent Childhood Cerebellar AstrocytomaRecurrent Childhood Cerebral Astrocytoma+19 more
National Cancer Institute (NCI) 30
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