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Results for “Refractory Systemic Sclerosis”

82 trials

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Showing 20 of 82 results

Early research (Phase 1)Looking for participantsNCT06980597
What this trial is testing

OL-108 in Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus Erythematosus (SLE)Idiopathic Inflammatory Myopathy (IIM)Systemic Sclerosis (SSc)+1 more
Beijing GoBroad Hospital 44
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07778446
What this trial is testing

Test CRT-402 in Refractory Autoimmune Disease

Who this might be right for
Autoimmune DiseasesSystemic Lupus ErythematosusSystemic Scleroderma+1 more
Myeloid Therapeutics 34
Very early researchNot Yet RecruitingNCT07583030
What this trial is testing

A Clinical Study to Evaluate LVIVO-TaVec400 for the Treatment of Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE)Relapsed/Refractory IgG4-Related Disease (r/r IgG4-RD)Progressive Multiple Sclerosis (PMS)+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 44
Early research (Phase 1)Ended earlyNCT05298358
What this trial is testing

RIC alloBMT With Post-transplant Cyclophosphamide for Refractory Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 1
Early research (Phase 1)Enrolling By InvitationNCT07038447
What this trial is testing

KITE-363 in Participants With Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusLupus NephritisSystemic Sclerosis+1 more
Kite, A Gilead Company 52
Early research (Phase 1)Not Yet RecruitingNCT07490275
What this trial is testing

Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Refractory/Relapsed Systemic Lupus ErythematosusRefractory / Relapsed / Progressive Systemic SclerosisRefractory / Relapsing / Progressive Inflammatory Myopathy+2 more
Institute of Hematology & Blood Diseases Hospital, China
Early research (Phase 1)Study completedNCT00010335
What this trial is testing

Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders

Who this might be right for
Systemic SclerosisSystemic Lupus ErythematosusDermatomyositis+2 more
Fred Hutchinson Cancer Center 6
Testing effectiveness (Phase 2)Looking for participantsNCT06828042
What this trial is testing

Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErthematosusSystemic Sclerosis (SSc)Sjogren Syndrome+3 more
Peking University Third Hospital 9
Not applicableLooking for participantsNCT07558850
What this trial is testing

Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune Diseases

Who this might be right for
Rheumatoid ArthritisDermatomyositisSystemic Lupus Erythematosus+1 more
The First Affiliated Hospital with Nanjing Medical University 72
Not applicableAvailableNCT04432545
What this trial is testing

Infusion of Allogeneic Mesenchymal Stem Cells in Patients With Diffuse Cutaneous Systemic Sclerosis With Refractory Pulmonary Involvement

Who this might be right for
Systemic Sclerosis PulmonaryPulmonary HypertensionPulmonary Fibrosis
Universidad de la Sabana
Early research (Phase 1)Looking for participantsNCT07167537
What this trial is testing

OL-CD19-GDT in Relapsed/ Refractory Autoimmune Diseases

Who this might be right for
Systemic Sclerosis (SSc)Primary Sjogren's Syndrome
Beijing GoBroad Hospital 44
Testing effectiveness (Phase 2)Looking for participantsNCT06794008
What this trial is testing

BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusInflammatory MyopathySystemic Sclerosis (SSc)+6 more
Peking University People's Hospital 50
Very early researchLooking for participantsNCT07355972
What this trial is testing

Safety, Efficacy and Cellular Metabolic Dynamics of CT1195E in Patients With Refractory / Progressive SSC

Who this might be right for
SSc-Systemic Sclerosis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 12
Testing effectiveness (Phase 2)Study completedNCT07542067
What this trial is testing

Infusion of Allogeneic Stromal Mesenchymal Stem Cells From Wharton´s Jelly in Patients With Diffuse Cutaneous Systemic Sclerosis With Refractory Pulmonary Involvement to Treatment

Who this might be right for
Systemic Sclerosis PulmonaryPulmonary HypertensionPulmonary Fibrosis
Fundación Neumologica Colombiana 1
Not applicableLooking for participantsNCT07121777
What this trial is testing

Anti CD19/BCMA CAR Gene Therapy for Autoimmune Diseases

Who this might be right for
Autoimmune Diseases
Anhui Provincial Hospital 18
Early research (Phase 1)Active Not RecruitingNCT06544330
What this trial is testing

SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease

Who this might be right for
Systemic Lupus ErythematosusLupus NephritisSystemic Sclerosis
Synthekine 48
Not applicableLooking for participantsNCT07470151
What this trial is testing

Clinical Study of EVM18001 in the Treatment of Refractory Autoimmune Diseases

Who this might be right for
System Lupus Erythematosus(SLE)SclerodermaMyasthenia Gravis (MG)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 12
Not applicableLooking for participantsNCT07052565
What this trial is testing

CAR-T Cells Therapy for Patients With Autoimmune Diseases

Who this might be right for
Autoimmune Diseases
Anhui Provincial Hospital 18
Very early researchNot Yet RecruitingNCT07674147
What this trial is testing

RD06-05 Universal CD19/BCMA CAR-T for Refractory Pediatric Autoimmune Diseases

Who this might be right for
Autoimmune DiseasesSLE - Systemic Lupus ErythematosusSSc-Systemic Sclerosis+3 more
The Children's Hospital of Zhejiang University School of Medicine 30
Not applicableLooking for participantsNCT06503224
What this trial is testing

An Exploratory Clinical Study of SCAR02 Targeting BCMA and CD19 for the Treatment of Refractory Autoimmune Diseases

Who this might be right for
Autoimmune Diseases
The First Affiliated Hospital of University of Science and Technology of China 18
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