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Results for “Refractory WHO Grade II Glioma”

33 trials

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Showing 20 of 33 results

Early research (Phase 1)Study completedNCT00006246
What this trial is testing

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorLeukemia+4 more
Pediatric Brain Tumor Consortium 28
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Early research (Phase 1)Study completedNCT00946335
What this trial is testing

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+25 more
National Cancer Institute (NCI) 31
Early research (Phase 1)Study completedNCT01076530
What this trial is testing

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System ChoriocarcinomaChildhood Central Nervous System Embryonal Tumor+31 more
National Cancer Institute (NCI) 27
Early research (Phase 1)Study completedNCT00015899
What this trial is testing

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 53
Early research (Phase 1)Study completedNCT00053963
What this trial is testing

FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia

Who this might be right for
Blastic Phase Chronic Myelogenous LeukemiaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Study completedNCT00503724
What this trial is testing

Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors

Who this might be right for
Brain and Central Nervous System TumorsNeuroblastoma
Pediatric Brain Tumor Consortium 32
Large-scale testing (Phase 3)Active Not RecruitingNCT04576117
What this trial is testing

Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Who this might be right for
Recurrent Low Grade AstrocytomaRecurrent WHO Grade 2 GliomaRefractory Low Grade Astrocytoma+2 more
National Cancer Institute (NCI) 300
Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Early research (Phase 1)Study completedNCT00098761
What this trial is testing

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

Who this might be right for
Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium 42
Testing effectiveness (Phase 2)Ended earlyNCT01836549
What this trial is testing

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAstrocytoma, Grade II+6 more
Pediatric Brain Tumor Consortium 43
Testing effectiveness (Phase 2)Active Not RecruitingNCT04195555
What this trial is testing

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Recurrent EpendymomaRecurrent Ewing SarcomaRecurrent Hepatoblastoma+30 more
National Cancer Institute (NCI) 3
Early research (Phase 1)Study completedNCT00303940
What this trial is testing

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorKidney Cancer+5 more
National Institutes of Health Clinical Center (CC) 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Testing effectiveness (Phase 2)Study completedNCT00004078
What this trial is testing

Irinotecan in Treating Children With Refractory Solid Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+18 more
Children's Oncology Group 181
Early research (Phase 1)Study completedNCT00030108
What this trial is testing

Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+7 more
National Institutes of Health Clinical Center (CC) 30
Early research (Phase 1)Study completedNCT00138216
What this trial is testing

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsUnspecified Childhood Solid Tumor, Protocol Specific
Children's Oncology Group 42
Early research (Phase 1)Study completedNCT00063973
What this trial is testing

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+23 more
National Cancer Institute (NCI) 24
Post-approval studies (Phase 4)Ended earlyNCT04650204
What this trial is testing

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Who this might be right for
Intractable EpilepsyMalignant GliomaSeizure Disorder+2 more
Mayo Clinic 4
Early research (Phase 1)Study completedNCT00326664
What this trial is testing

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Cerebral Anaplastic Astrocytoma+18 more
National Cancer Institute (NCI) 55
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