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Results for “Refractory and/or Relapsed Metastatic Solid Tumors”

82 trials

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Showing 20 of 82 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Testing effectiveness (Phase 2)Study completedNCT03711058
What this trial is testing

Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer

Who this might be right for
Unresectable or Metastatic Microsatellite Stable (MSS) Solid TumorMicrosatellite Stable (MSS) Colon Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 48
Early research (Phase 1)Study completedNCT01231919
What this trial is testing

MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Leukemias of Ambiguous LineageAcute Myeloid Leukemia/Transient Myeloproliferative Disorder+48 more
National Cancer Institute (NCI) 45
Early research (Phase 1)Not Yet RecruitingNCT06383507
What this trial is testing

A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors

Who this might be right for
Metastatic TumorAdvanced Solid TumorRenal Cell Carcinoma+4 more
Zhejiang University 18
Early research (Phase 1)Active Not RecruitingNCT05104775
What this trial is testing

GNC-035, a Tetra-specific Antibody, in Participants With Relapsed/Refractory Hematologic Malignancy

Who this might be right for
Hematologic Malignancies
Sichuan Baili Pharmaceutical Co., Ltd. 33
Early research (Phase 1)Looking for participantsNCT05631886
What this trial is testing

Combination of CAR-DC Vaccine and ICIs in Malignant Tumors

Who this might be right for
Solid Tumor, AdultLymphomaEphA2 Overexpression+4 more
Chinese PLA General Hospital 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT01012817
What this trial is testing

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

Who this might be right for
Metastatic Malignant Solid NeoplasmRecurrent Fallopian Tube CarcinomaRecurrent Ovarian Carcinoma+2 more
National Cancer Institute (NCI) 88
Large-scale testing (Phase 3)Study completedNCT00666211
What this trial is testing

Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Vanderbilt-Ingram Cancer Center 98
Early research (Phase 1)Looking for participantsNCT06063681
What this trial is testing

SR-8541A (ENPPI Inhibitor) in Advanced/Metastatic Solid Tumors

Who this might be right for
Advanced / Metastatic Solid Tumor
Stingray Therapeutics 25
Early research (Phase 1)Study completedNCT04678921
What this trial is testing

Study of TJ210001 Administered in Subjects With Relapsed or Refractory Advanced Solid Tumors

Who this might be right for
Solid TumorMetastatic CancerAdvanced Cancer
I-Mab Biopharma US Limited 16
Early research (Phase 1)Study completedNCT04349969
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK117 as Monotherapy or in Combination With AK104

Who this might be right for
Neoplasms Malignant
Akesobio Australia Pty Ltd 38
Early research (Phase 1)Ended earlyNCT02408861
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
Advanced Malignant Solid NeoplasmAnal CarcinomaHIV Infection+7 more
National Cancer Institute (NCI) 79
Early research (Phase 1)Study completedNCT03017833
What this trial is testing

Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmRecurrent Malignant Solid Neoplasm+1 more
M.D. Anderson Cancer Center 31
Early research (Phase 1)Study completedNCT00104962
What this trial is testing

Lenalidomide in Treating Young Patients With Relapsed or Refractory Solid Tumors or Myelodysplastic Syndromes

Who this might be right for
Childhood Myelodysplastic Syndromesde Novo Myelodysplastic SyndromesPreviously Treated Myelodysplastic Syndromes+6 more
National Cancer Institute (NCI) 24
Large-scale testing (Phase 3)Study completedNCT00003687
What this trial is testing

Treatment for Chronic Pain in Patients With Advanced Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+6 more
NCIC Clinical Trials Group 87
Early research (Phase 1)Study completedNCT03884556
What this trial is testing

TTX-030 Single Agent and in Combination With Immunotherapy or Chemotherapy for Patients With Advanced Cancers

Who this might be right for
Solid TumorLymphoma
Trishula Therapeutics, Inc. 56
Testing effectiveness (Phase 2)UnknownNCT04458389
What this trial is testing

TY101 for Locally Advanced /Metastatic Solid Tumors and Relapsed or Refractory Lymphomas

Who this might be right for
Locally Advanced /Metastatic Solid TumorsRelapsed or Refractory Lymphomas
Tayu Huaxia Biotech Medical Group Co., Ltd. 268
Testing effectiveness (Phase 2)Ended earlyNCT04775680
What this trial is testing

Study of ADG106 In Combination With PD-1 Antibody In Advanced or Metastatic Solid Tumors and/or Non Hodgkin Lymphoma

Who this might be right for
Solid TumorNon Hodgkin Lymphoma
Adagene (Suzhou) Limited 25
Early research (Phase 1)Study completedNCT03510104
What this trial is testing

Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid Tumors

Who this might be right for
Advanced CancerMetastatic CancerNeoplasms+3 more
Meryx, Inc. 42
Testing effectiveness (Phase 2)WithdrawnNCT01101412
What this trial is testing

Antimicrobial Solution or Saline Solution in Maintaining Catheter Patency and Preventing Catheter-Related Blood Infections in Patients With Malignancies

Who this might be right for
Chronic Myeloproliferative DisordersInfectionLeukemia+6 more
M.D. Anderson Cancer Center
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