Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Regulatory T Cell Depletion”

24 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 24 results

Testing effectiveness (Phase 2)UnknownNCT02519816
What this trial is testing

Continuous Alloreactive T Cell Depletion and Regulatory T Cell Expansion for the Treatment of Steroid-refractory or Dependent Chronic GVHD

Who this might be right for
Chronic GVHD After HCT for Cancer or Immune Disease
daphne brockington 17
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06180499
What this trial is testing

Allogeneic Immunotherapy of Hematological Malignancies Using Regulatory T-cell Selective Depletion

Who this might be right for
Hematological MalignanciesRegulatory T Cell DepletionRelapse
Assistance Publique - Hôpitaux de Paris 27
Large-scale testing (Phase 3)UnknownNCT03236129
What this trial is testing

Allogeneic Immunotherapy for Hematological Malignancies by Selective Depletion of Regulatory T Cells

Who this might be right for
Hematological MalignanciesRegulatory T Cell DepletionRelapse
Assistance Publique - Hôpitaux de Paris 52
Testing effectiveness (Phase 2)Study completedNCT01660607
What this trial is testing

Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

Who this might be right for
Myeloid Leukemia, ChronicAcute Myelogenous LeukemiaMyelodysplastic Syndromes (MDS)+6 more
Stanford University 68
Testing effectiveness (Phase 2)Looking for participantsNCT06839456
What this trial is testing

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Who this might be right for
LeukemiaHigh Risk Acute Lymphoblastic LeukemiaHigh Risk Acute Myeloid Leukemia+11 more
Children's Hospital of Philadelphia 100
Large-scale testing (Phase 3)Looking for participantsNCT07366801
What this trial is testing

Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia, RelapsedAcute Lymphoblastic Leukemia, High RiskAcute Myeloid Leukemia, High Risk+1 more
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Early research (Phase 1)WithdrawnNCT00224354
What this trial is testing

Lymphocytic B-Leukemia (B-CLL) w/Human IL-2 Gene Modified & Human CD40 Ligand-Expressing Autologous Tumor Cells

Who this might be right for
CHRONIC LYMPHOCYTIC B-LEUKEMIA
Baylor College of Medicine
Testing effectiveness (Phase 2)Ended earlyNCT02009384
What this trial is testing

Ipilimumab Administered to Stage IIIC Stage IV Melanoma After Reg. T Cell Depletion With Denileukin Diftitox

Who this might be right for
Metastatic Melanoma
University of Louisville 2
Large-scale testing (Phase 3)Active Not RecruitingNCT05316701
What this trial is testing

Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoid LeukemiaMixed Phenotype Acute Leukemia+4 more
Orca Biosystems, Inc. 187
Early research (Phase 1)Study completedNCT00128622
What this trial is testing

Denileukin Diftitox Followed by Vaccine Therapy in Treating Patients With Metastatic Cancer

Who this might be right for
Breast CancerColorectal CancerLung Cancer+2 more
H. Kim Lyerly 24
Testing effectiveness (Phase 2)Ended earlyNCT00138229
What this trial is testing

Cyclophosphamide and Fludarabine Followed By an Autologous Lymphocyte Infusion and Interleukin-2 in Treating Patients With Refractory or Recurrent Metastatic Melanoma

Who this might be right for
Melanoma (Skin)
National Institutes of Health Clinical Center (CC) 6
Testing effectiveness (Phase 2)Ended earlyNCT00303836
What this trial is testing

Vaccine Therapy With or Without Interleukin-2 After Chemotherapy and an Autologous White Blood Cell Infusion in Treating Patients With Metastatic Melanoma

Who this might be right for
Recurrent MelanomaStage IV Melanoma
National Cancer Institute (NCI) 58
Testing effectiveness (Phase 2)Study completedNCT00987987
What this trial is testing

Amplifying Graft-Versus-Tumor Effect by Donor Regulatory T-Cell Depletion Before Donor Lymphocytes Infusion

Who this might be right for
Hematologic NeoplasmsRelapse
Assistance Publique - Hôpitaux de Paris 21
Early research (Phase 1)Study completedNCT00675831
What this trial is testing

Infusion of Donor Lymphocytes Depleted of CD25+ Regulatory T-cells in Patients With Relapsed Hematologic Malignancies

Who this might be right for
Hematologic Malignancies
Dana-Farber Cancer Institute 24
Early research (Phase 1)Active Not RecruitingNCT04013685
What this trial is testing

Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoid LeukemiaMyelodysplastic Syndromes+3 more
Orca Biosystems, Inc. 155
Testing effectiveness (Phase 2)Active Not RecruitingNCT05200559
What this trial is testing

T-regulatory Cell Depletion With E7777 Combined With Pembrolizumab in Recurrent or Metastatic Solid Tumors

Who this might be right for
Epithelial Ovarian Cancer
Alexander B Olawaiye, MD 25
Testing effectiveness (Phase 2)Ended earlyNCT00515528
What this trial is testing

Vaccination Plus Ontak in Patients With Metastatic Melanoma

Who this might be right for
Melanoma
University of Chicago 17
Testing effectiveness (Phase 2)WithdrawnNCT01163201
What this trial is testing

T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignancies

Who this might be right for
Hematologic MalignancyAcute Myeloid LeukemiaAcute Lymphocytic Leukemia+14 more
Masonic Cancer Center, University of Minnesota
Testing effectiveness (Phase 2)Study completedNCT00986518
What this trial is testing

T Regulatory Lymphocytes (Treg) Depletion for Cancer Treatment Efficacy and Safety Study

Who this might be right for
Colorectal Cancer
Assistance Publique - Hôpitaux de Paris 5
Testing effectiveness (Phase 2)UnknownNCT01513109
What this trial is testing

Safety and Immunogenicity of Recombinant WT1 Antigen-Specific Cancer Immunotherapeutic Combined With Infusion of Treg Depleted T Cells for Adult WT1 Acute Myeloid Leukemia

Who this might be right for
Acute Myelogenous LeukemiaMyeloid Leukemia in RemissionEffects of Immunotherapy
Jules Bordet Institute 20
Load More Results
64