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Results for “Relapsed/Refractory CD19-positive B-ALL”

50 trials

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Showing 20 of 50 results

Very early researchLooking for participantsNCT07470073
What this trial is testing

A Clinical Study Exploring the Safety, Efficacy and Cell Metabolic Kinetics of Universal Car-t Cell Injection in CD19 and / or CD20 Positive Relapsed / Refractory B-cell Acute Lymphoblastic Leukemia in Adolescents, Children and Adults

Who this might be right for
ALL (Acute B-Lymphoblastic Leukemia)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 18
Very early researchUnknownNCT06393335
What this trial is testing

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research

Who this might be right for
Acute Lymphoblastic LeukemiaNon-hodgkin Lymphoma
The Children's Hospital of Zhejiang University School of Medicine 36
Very early researchLooking for participantsNCT07205315
What this trial is testing

A Clinical Study Evaluating the Safety and Efficacy of GT801 Injection in Adult Patients With Relapsed/Refractory CD19-positive B-cell Hematologic Malignancies and Autoimmune Hemolytic Anemia

Who this might be right for
B-cell Acute Lymphoblastic Leukemia (B-ALL)Chronic Lymphocytic Leukemia (CLL)B-cell Non-Hodgkin's Lymphoma (B-NHL)+1 more
Grit Biotechnology 28
Early research (Phase 1)Not Yet RecruitingNCT07491263
What this trial is testing

Clinical Study of Universal CD19 CAR-γδ T Cell Infusion in the Treatment of Relapsed/Refractory Acute B Lymphoblastic Leukemia

Who this might be right for
Relapsed/Refractory CD19-positive B-ALL
Fujian Medical University 6
Testing effectiveness (Phase 2)Study completedNCT03289455
What this trial is testing

CD19 /22 CAR T Cells (AUTO3) for the Treatment of B Cell Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
B Acute Lymphoblastic LeukemiaRecurrent Childhood Acute Lymphoblastic LeukemiaRefractory Childhood Acute Lymphoblastic Leukemia+1 more
Autolus Limited 23
Testing effectiveness (Phase 2)Looking for participantsNCT07584889
What this trial is testing

Efficacy and Safety of CD19-CAR.p40-T in Patients With Relapsed/Refractory CD19-Positive Hematologic Malignancies

Who this might be right for
B Cell LymphomaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia
Shenzhen University General Hospital 10
Not applicableNot Yet RecruitingNCT07637929
What this trial is testing

Non-Interventional Study of Puzol-cel for CD19-Positive Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia

Who this might be right for
Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia (r/r B-ALL)
Chongqing Precision Biotech Co., Ltd 200
Early research (Phase 1)Study completedNCT05563545
What this trial is testing

Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Shanghai Simnova Biotechnology Co.,Ltd. 2
Testing effectiveness (Phase 2)Study completedNCT01865617
What this trial is testing

Laboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, or Acute Lymphoblastic Leukemia

Who this might be right for
CD19-Positive Neoplastic Cells PresentRecurrent Adult Acute Lymphoblastic LeukemiaRecurrent Chronic Lymphocytic Leukemia+10 more
Fred Hutchinson Cancer Center 204
Not applicableLooking for participantsNCT06355739
What this trial is testing

CD19-targeted CAR T Cell Autotransfusion for the Treatment of Recurrent/Refractory B-cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma in Children With CD19+

Who this might be right for
B Lymphocytic LeukemiaB Lymphoblastic Lymphoma
Zhu Xiaofan 60
Very early researchStudy completedNCT04689204
What this trial is testing

CTA30X Cell Injection in Patients With Relapsed or Refractory CD19-positive B-line Hematological Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaNon-hodgkin Lymphoma
He Huang 3
Early research (Phase 1)UnknownNCT04037566
What this trial is testing

CRISPR (HPK1) Edited CD19-specific CAR-T Cells (XYF19 CAR-T Cells) for CD19+ Leukemia or Lymphoma.

Who this might be right for
Leukemia Lymphocytic Acute (ALL) in RelapseLeukemia Lymphocytic Acute (All) RefractoryLymphoma, B-Cell+1 more
Xijing Hospital 40
Early research (Phase 1)Not Yet RecruitingNCT06641024
What this trial is testing

Clinical Research of CD19 Targeted CAR-T Cell in Relapsed/ Refractory B-ALL

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseRefractory Acute Lymphoblastic Leukemia
Chongqing Precision Biotech Co., Ltd 24
Early research (Phase 1)Not Yet RecruitingNCT07043218
What this trial is testing

A Clinical Study Exploring Universal CAR-T Cell in Patients With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Shanghai Tongji Hospital, Tongji University School of Medicine 36
Testing effectiveness (Phase 2)Looking for participantsNCT05366218
What this trial is testing

Tafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia

Who this might be right for
ALL, Childhood B-CellAcute Lymphoid Leukemia RelapseAcute Lymphocytic Leukemia Refractory
University Hospital Tuebingen 20
Not applicableLooking for participantsNCT06866873
What this trial is testing

CD-19 CAR-T Cell for Pediatric ALL or Lymphoma

Who this might be right for
Lymphoma, B-CellAcute Lymphoblastic Leukemia, Pediatric
Hong Kong Children's Hospital 18
Early research (Phase 1)Looking for participantsNCT06287528
What this trial is testing

19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Philadelphia-Negative ALLPhiladelphia-Positive ALLRelapsed ALL, Adult+3 more
Memorial Sloan Kettering Cancer Center 18
Early research (Phase 1)Looking for participantsNCT05705570
What this trial is testing

Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia RefractoryB-cell Lymphoma Recurrent+3 more
Nelson Hamerschlak 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04404660
What this trial is testing

CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)

Who this might be right for
Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
Autolus Limited 153
Testing effectiveness (Phase 2)UnknownNCT02819583
What this trial is testing

CAR-T Cell Immunotherapy in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma

Who this might be right for
Acute Lymphocytic LeukemiaChronic Lymphocytic LeukemiaFollicular Lymphoma+3 more
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
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